GB1043153A - Quinazoline derivatives - Google Patents

Quinazoline derivatives

Info

Publication number
GB1043153A
GB1043153A GB5145564A GB5145564A GB1043153A GB 1043153 A GB1043153 A GB 1043153A GB 5145564 A GB5145564 A GB 5145564A GB 5145564 A GB5145564 A GB 5145564A GB 1043153 A GB1043153 A GB 1043153A
Authority
GB
United Kingdom
Prior art keywords
quinazoline derivatives
alkyl
formula
sulphonyloxyacetyl
arylsulphonyloxyacetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5145564A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical Co filed Critical Warner Lambert Pharmaceutical Co
Publication of GB1043153A publication Critical patent/GB1043153A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Compounds of the general formula <FORM:1043153/C2/1> (wherein R3 is a C1- 6 alkyl or a monocyclic aryl group and R4 is a halogen atom) are prepared by condensing the corresponding alkyl-sulphonyloxyacetyl or arylsulphonyloxyacetyl chloride with a compound of the formula <FORM:1043153/C2/2> followed by ring closure.
GB5145564A 1962-04-09 1963-04-03 Quinazoline derivatives Expired GB1043153A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20430162A 1962-04-09 1962-04-09

Publications (1)

Publication Number Publication Date
GB1043153A true GB1043153A (en) 1966-09-21

Family

ID=22757364

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1316063A Expired GB1043152A (en) 1962-04-09 1963-04-03 1,4-benzodiazepines and preparation thereof
GB5145564A Expired GB1043153A (en) 1962-04-09 1963-04-03 Quinazoline derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1316063A Expired GB1043152A (en) 1962-04-09 1963-04-03 1,4-benzodiazepines and preparation thereof

Country Status (5)

Country Link
BR (1) BR6348317D0 (en)
CH (3) CH394221A (en)
DE (2) DE1620709A1 (en)
DK (3) DK106229C (en)
GB (2) GB1043152A (en)

Also Published As

Publication number Publication date
BR6348317D0 (en) 1973-07-03
DE1620709A1 (en) 1970-06-04
DK107555C (en) 1967-06-12
CH394221A (en) 1965-06-30
DK105472C (en) 1966-10-03
CH408032A (en) 1966-02-28
GB1043152A (en) 1966-09-21
CH408031A (en) 1966-02-28
DK106229C (en) 1967-01-09
DE1470414A1 (en) 1969-11-13

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