ES354410A1 - Procedimiento de fabricacion de nuevos medios de contraste radiologico. - Google Patents
Procedimiento de fabricacion de nuevos medios de contraste radiologico.Info
- Publication number
- ES354410A1 ES354410A1 ES354410A ES354410A ES354410A1 ES 354410 A1 ES354410 A1 ES 354410A1 ES 354410 A ES354410 A ES 354410A ES 354410 A ES354410 A ES 354410A ES 354410 A1 ES354410 A1 ES 354410A1
- Authority
- ES
- Spain
- Prior art keywords
- prepared
- reacting
- alkylene
- ester
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002872 contrast media Substances 0.000 title abstract 2
- 238000009606 cholecystography Methods 0.000 title 1
- 229940039231 contrast media Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- FKRCODPIKNYEAC-UHFFFAOYSA-N propionic acid ethyl ester Natural products CCOC(=O)CC FKRCODPIKNYEAC-UHFFFAOYSA-N 0.000 abstract 3
- 150000001733 carboxylic acid esters Chemical group 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- KLLOEOPUXBJSOW-UHFFFAOYSA-N 3-(methylamino)phenol Chemical compound CNC1=CC=CC(O)=C1 KLLOEOPUXBJSOW-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- BPLPANYMHXJFOX-UHFFFAOYSA-N N-(3-hydroxy-2,4,6-triiodophenyl)acetamide Chemical compound CC(=O)NC1=C(I)C=C(I)C(O)=C1I BPLPANYMHXJFOX-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- -1 amine salt Chemical class 0.000 abstract 1
- 229940073608 benzyl chloride Drugs 0.000 abstract 1
- BFVNGHJRLLUPHY-UHFFFAOYSA-N bis(2-chloroethoxy)methylbenzene Chemical compound ClCCOC(OCCCl)C1=CC=CC=C1 BFVNGHJRLLUPHY-UHFFFAOYSA-N 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- DOBRDRYODQBAMW-UHFFFAOYSA-N copper(i) cyanide Chemical compound [Cu+].N#[C-] DOBRDRYODQBAMW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- VIPCILFKUBQRCQ-UHFFFAOYSA-N n-(2-hydroxyphenyl)propanamide Chemical compound CCC(=O)NC1=CC=CC=C1O VIPCILFKUBQRCQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 235000019260 propionic acid Nutrition 0.000 abstract 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0495—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound intended for oral administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH748267A CH483262A (de) | 1967-05-29 | 1967-05-29 | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES354410A1 true ES354410A1 (es) | 1969-11-01 |
Family
ID=4325807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES354410A Expired ES354410A1 (es) | 1967-05-29 | 1968-05-28 | Procedimiento de fabricacion de nuevos medios de contraste radiologico. |
Country Status (12)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314055A (en) * | 1975-09-29 | 1982-02-02 | Mallinckrodt, Inc. | 3,5-Disubstituted-2,4,6-triiodoanilides of polyhydroxy-monobasic acids |
| US5348727A (en) * | 1993-03-11 | 1994-09-20 | Sterling Winthrop Inc. | Compositions of iodophenoxy alkylene ethers for visualization of the gastrointestinal tract |
| US5310538A (en) * | 1993-03-11 | 1994-05-10 | Sterling Winthrop Inc. | Compositions of iodophenoxy alkylene ethers in film-forming materials for visualization of the gastrointestinal tract |
-
1967
- 1967-05-29 CH CH1533669A patent/CH494576A/de unknown
- 1967-05-29 CH CH748267A patent/CH483262A/de not_active IP Right Cessation
-
1968
- 1968-05-02 SE SE05927/68A patent/SE352340B/xx unknown
- 1968-05-07 GB GB1228851D patent/GB1228851A/en not_active Expired
- 1968-05-14 DK DK223568AA patent/DK123762B/da unknown
- 1968-05-14 US US728894A patent/US3553259A/en not_active Expired - Lifetime
- 1968-05-16 NO NO1936/68A patent/NO121611B/no unknown
- 1968-05-24 NL NL6807381A patent/NL6807381A/xx unknown
- 1968-05-25 DE DE19681768553 patent/DE1768553B1/de not_active Withdrawn
- 1968-05-27 AT AT60669A patent/AT284825B/de not_active IP Right Cessation
- 1968-05-27 AT AT506668A patent/AT277452B/de not_active IP Right Cessation
- 1968-05-28 FR FR1596453D patent/FR1596453A/fr not_active Expired
- 1968-05-28 ES ES354410A patent/ES354410A1/es not_active Expired
- 1968-05-28 BE BE715799D patent/BE715799A/xx unknown
- 1968-05-28 FR FR153106A patent/FR7769M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3553259A (en) | 1971-01-05 |
| DK123762B (da) | 1972-07-31 |
| FR7769M (enrdf_load_stackoverflow) | 1970-03-23 |
| FR1596453A (enrdf_load_stackoverflow) | 1970-06-22 |
| AT277452B (de) | 1969-12-29 |
| NL6807381A (enrdf_load_stackoverflow) | 1968-12-02 |
| DE1768553B1 (de) | 1970-09-16 |
| SE352340B (enrdf_load_stackoverflow) | 1972-12-27 |
| GB1228851A (enrdf_load_stackoverflow) | 1971-04-21 |
| BE715799A (enrdf_load_stackoverflow) | 1968-11-28 |
| CH483262A (de) | 1969-12-31 |
| CH494576A (de) | 1970-08-15 |
| NO121611B (enrdf_load_stackoverflow) | 1971-03-22 |
| AT284825B (de) | 1970-09-25 |
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