ES340132A1 - Ampicillin trihydrate - Google Patents
Ampicillin trihydrateInfo
- Publication number
- ES340132A1 ES340132A1 ES340132A ES340132A ES340132A1 ES 340132 A1 ES340132 A1 ES 340132A1 ES 340132 A ES340132 A ES 340132A ES 340132 A ES340132 A ES 340132A ES 340132 A1 ES340132 A1 ES 340132A1
- Authority
- ES
- Spain
- Prior art keywords
- ampicillin
- water
- trihydrate
- produce
- organic solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Ampicillin trihydrate is prepared by precipitating ampicillin in the form of a hydrate thereof containing at least one but less than three molecules of water per molecule of ampicillin from a solution of ampicillin in an aqueous water-miscible polar organic solvent medium, said medium containing up to 20% by volume of water and subsequently treating the resulting precipitate with an excess of water to produce ampicillin trihydrate. Ampicillin may be dissolved in aqueous acetone at pH 1 to 4, clarified and an inorganic or organic base added to pH 4 to 7 until a precipitate forms. This is washed with an organic solvent and then treated with excess water in order to produce the trihydrate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1345067 | 1967-03-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES340132A1 true ES340132A1 (en) | 1968-08-16 |
Family
ID=11144453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES340132A Expired ES340132A1 (en) | 1967-03-08 | 1967-05-03 | Ampicillin trihydrate |
Country Status (8)
Country | Link |
---|---|
AT (1) | AT287192B (en) |
DE (1) | DE1645980A1 (en) |
DK (1) | DK119979B (en) |
ES (1) | ES340132A1 (en) |
FR (1) | FR1557644A (en) |
GB (1) | GB1216714A (en) |
GR (1) | GR37429B (en) |
NL (1) | NL6705789A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3703511A (en) * | 1969-06-06 | 1972-11-21 | Squibb & Sons Inc | Alpha-aminobenzyl penicillins |
JPS6379888A (en) * | 1986-09-24 | 1988-04-09 | Tanabe Seiyaku Co Ltd | Stable hydrate of penicillin derivative |
AR062927A1 (en) | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4- ([[4- CHLORINE-3- (TRIFLUOROMETILE) PHENYL) CARBAMOIL] AMINO] -3- FLUOROPHENOXY) -N- METHYLPIRIDIN-2-MONOHIDRATED CARBOXAMIDE |
-
1967
- 1967-04-25 NL NL6705789A patent/NL6705789A/xx unknown
- 1967-05-03 ES ES340132A patent/ES340132A1/en not_active Expired
- 1967-06-21 DE DE19671645980 patent/DE1645980A1/en active Pending
- 1967-06-22 FR FR1557644D patent/FR1557644A/fr not_active Expired
- 1967-06-26 GR GR670137429A patent/GR37429B/en unknown
-
1968
- 1968-02-28 AT AT193368A patent/AT287192B/en not_active IP Right Cessation
- 1968-03-07 DK DK95068A patent/DK119979B/en unknown
- 1968-03-08 GB GB1152868A patent/GB1216714A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR1557644A (en) | 1969-02-21 |
GB1216714A (en) | 1970-12-23 |
GR37429B (en) | 1969-05-29 |
NL6705789A (en) | 1968-09-09 |
DK119979B (en) | 1971-03-22 |
AT287192B (en) | 1971-01-11 |
DE1645980A1 (en) | 1970-07-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1302537A (en) | ||
ES340132A1 (en) | Ampicillin trihydrate | |
AT274349B (en) | Process for the preparation of aqueous solutions containing high molecular weight polyacrylamide and sodium polyacrylate | |
ES312167A1 (en) | A procedure to electrolytically attack an aluminum sheet. (Machine-translation by Google Translate, not legally binding) | |
GB1271449A (en) | Production of iron oxide pigments | |
ES348097A1 (en) | Process for the production of an intramuscularly injectable iron preparation for animals | |
GB1033189A (en) | Gelatin derivatives | |
ES300658A1 (en) | Procedure for the production of a new polipepturo (Machine-translation by Google Translate, not legally binding) | |
KR890014583A (en) | Method for producing latex based on polypyrrole and use of the latex to form conductive films | |
ES309594A1 (en) | Improvements introduced in the manufacture of coating compositions to provide a hydrophyl layer. (Machine-translation by Google Translate, not legally binding) | |
SE308902B (en) | ||
GB1225599A (en) | ||
GB1156738A (en) | Printing and Dyeing Processes | |
GB1251761A (en) | ||
ES296050A1 (en) | A procedure to produce bright nickel deposits (Machine-translation by Google Translate, not legally binding) | |
GB830011A (en) | Improvements in and relating to the polymerisation of vinyl compounds | |
GB974128A (en) | Kanamycin complex salts | |
GB1127861A (en) | Process for the preparation of 2-oxo-tetrahydroimidazole compounds | |
ES282912A1 (en) | Procedure to produce coloring preparations (Machine-translation by Google Translate, not legally binding) | |
GB1233643A (en) | ||
ES386715A1 (en) | Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding) | |
ES299426A1 (en) | Procedure for obtaining new derivatives of bio and semisynthetic penicillines (Machine-translation by Google Translate, not legally binding) | |
ES331877A1 (en) | Procedure for treating a synthetic fiber of acrylonitril. (Machine-translation by Google Translate, not legally binding) | |
GB1021112A (en) | A new salt and a new process for the recovery of kanamycin | |
Iida et al. | Basic Studies on the Clarification of Waste Water Containing Dyes. I. Precipitation of Direct Dyes by Ferric Chloride |