ES339155A1 - Procedimiento para la produccion de compuestos relacionadoscon prostaglandinas. - Google Patents
Procedimiento para la produccion de compuestos relacionadoscon prostaglandinas.Info
- Publication number
- ES339155A1 ES339155A1 ES339155A ES339155A ES339155A1 ES 339155 A1 ES339155 A1 ES 339155A1 ES 339155 A ES339155 A ES 339155A ES 339155 A ES339155 A ES 339155A ES 339155 A1 ES339155 A1 ES 339155A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- alkyl
- signifies
- oxo
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 17
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- -1 hydrocarbon carboxylic acid Chemical class 0.000 abstract 7
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- VUDZSIYXZUYWSC-DBRKOABJSA-N (4r)-1-[(2r,4r,5r)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Chemical compound FC1(F)[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)N[C@H](O)CC1 VUDZSIYXZUYWSC-DBRKOABJSA-N 0.000 abstract 1
- MZRSAJZDYIISJW-UHFFFAOYSA-N 1-phenyl-2-(triphenyl-$l^{5}-phosphanylidene)ethanone Chemical compound C=1C=CC=CC=1C(=O)C=P(C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 MZRSAJZDYIISJW-UHFFFAOYSA-N 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- XYDYWTJEGDZLTH-UHFFFAOYSA-N methylenetriphenylphosphorane Chemical compound C=1C=CC=CC=1P(C=1C=CC=CC=1)(=C)C1=CC=CC=C1 XYDYWTJEGDZLTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000002997 prostaglandinlike Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54147766A | 1966-04-11 | 1966-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES339155A1 true ES339155A1 (es) | 1968-04-16 |
Family
ID=24159749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES339155A Expired ES339155A1 (es) | 1966-04-11 | 1967-04-01 | Procedimiento para la produccion de compuestos relacionadoscon prostaglandinas. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3505387A (forum.php) |
| BE (1) | BE696888A (forum.php) |
| DE (1) | DE1643159A1 (forum.php) |
| ES (1) | ES339155A1 (forum.php) |
| FR (1) | FR7145M (forum.php) |
| GB (3) | GB1183842A (forum.php) |
| GR (1) | GR34716B (forum.php) |
| NL (1) | NL6703617A (forum.php) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959346A (en) * | 1969-03-14 | 1976-05-25 | The Upjohn Company | Racemic prostaglandins of the 2-series and analogs thereof |
| US3935261A (en) * | 1970-01-23 | 1976-01-27 | May & Baker Limited | Cyclopentane derivatives |
| BE793535A (fr) * | 1971-12-30 | 1973-06-29 | Upjohn Co | Nouveaux derives de prostaglandines et leur procede de preparation |
| US3922293A (en) * | 1971-12-30 | 1975-11-25 | Upjohn Co | Prostaglandin F-type 9-monoacylates |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3432541A (en) * | 1965-09-08 | 1969-03-11 | American Home Prod | 9,15-dihydroxyprost-13-enoic acid and ester and preparation thereof |
-
1966
- 1966-04-11 US US541477A patent/US3505387A/en not_active Expired - Lifetime
-
1967
- 1967-02-24 GR GR670134716A patent/GR34716B/el unknown
- 1967-03-08 NL NL6703617A patent/NL6703617A/xx unknown
- 1967-03-16 DE DE19671643159 patent/DE1643159A1/de active Pending
- 1967-03-28 GB GB44255/69A patent/GB1183842A/en not_active Expired
- 1967-03-28 GB GB04128/67A patent/GB1183841A/en not_active Expired
- 1967-03-28 GB GB44256/69A patent/GB1183843A/en not_active Expired
- 1967-04-01 ES ES339155A patent/ES339155A1/es not_active Expired
- 1967-04-11 BE BE696888D patent/BE696888A/xx unknown
- 1967-07-07 FR FR113557A patent/FR7145M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR34716B (el) | 1968-06-14 |
| GB1183841A (en) | 1970-03-11 |
| GB1183842A (en) | 1970-03-11 |
| DE1643159A1 (de) | 1971-05-13 |
| BE696888A (forum.php) | 1967-10-11 |
| NL6703617A (forum.php) | 1967-10-12 |
| FR7145M (forum.php) | 1969-07-28 |
| GB1183843A (en) | 1970-03-11 |
| US3505387A (en) | 1970-04-07 |
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