ES333484A1 - Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES333484A1
ES333484A1 ES0333484A ES333484A ES333484A1 ES 333484 A1 ES333484 A1 ES 333484A1 ES 0333484 A ES0333484 A ES 0333484A ES 333484 A ES333484 A ES 333484A ES 333484 A1 ES333484 A1 ES 333484A1
Authority
ES
Spain
Prior art keywords
formula
general formula
group
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0333484A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES333484A1 publication Critical patent/ES333484A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for the preparation of new substituted urea derivatives, of the general formula ** (See formula) ** in which X means the methylene or ethylenic group, oxygen, the imino group or an alkylimino or lower alkanoylimino group, And it means oxygen or sulfur, R1, R2 and R3 mean hydrogen or a lower alkyl group, R3 and R4 mean hydrogen, halogen up to the atomic number 35, trifluoromethyl groups or alkyl, alkoxy, or lower alkanoyl groups, and n is 0 or 1, characterized in that an amine of the general formula II is reacted ** (See formula) ** in which X 'has the significance indicated under formula I for X excluding the imino group, and R1, R5 and n have the meanings already indicated, with an isocyanate or phenyl isothiocyanate of the general formula III ** (See formula) ** or with a functional derivative suitable for the reaction of a carbanyl or thiocarbenzyl acid of the general formula IV ** (See formula) ** in which And, R2, R3 and R4 have the significance indicated under formula I, and if desired a lower alkanoyl radical which is found in X 'is split by hydrolysis. (Machine-translation by Google Translate, not legally binding)
ES0333484A 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES333484A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1590965A CH456570A (en) 1965-11-18 1965-11-18 Process for the production of new substituted urea derivatives

Publications (1)

Publication Number Publication Date
ES333484A1 true ES333484A1 (en) 1967-12-01

Family

ID=4412947

Family Applications (4)

Application Number Title Priority Date Filing Date
ES0333484A Expired ES333484A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES0333487A Expired ES333487A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES0333485A Expired ES333485A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES333486A Expired ES333486A1 (en) 1965-11-18 1966-11-17 Novel urea derivatives and their production

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES0333487A Expired ES333487A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES0333485A Expired ES333485A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES333486A Expired ES333486A1 (en) 1965-11-18 1966-11-17 Novel urea derivatives and their production

Country Status (10)

Country Link
AT (2) AT267540B (en)
BE (1) BE689823A (en)
CH (1) CH456570A (en)
DE (1) DE1246722B (en)
ES (4) ES333484A1 (en)
FR (2) FR1504098A (en)
GB (1) GB1125559A (en)
NL (1) NL6616214A (en)
NO (1) NO119270B (en)
SE (1) SE325024B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3621100A (en) * 1965-11-18 1971-11-16 Geigy Chem Corp Composition and method for producing a tuberculostatic effect
US3615941A (en) * 1968-05-07 1971-10-26 Hitachi Ltd Method for manufacturing semiconductor device with passivation film
BE758165A (en) * 1969-10-28 1971-04-28 Cilag Chemie ADAMANTYLURIDES AND METHODS FOR PREPARING THEM
ES2037768T3 (en) * 1987-07-02 1993-07-01 Warner-Lambert Company PROCEDURE FOR PREPARING N- (FENYL (2,6-DISSTITUTED)) - UREAS AND CARBAMATES INHIBITING ACIL-COA: CHOLESTEROL ACIL-TRANSFERASE.
CN100448863C (en) * 2003-07-24 2009-01-07 默克公司 Antibiotic compound
HRP20090186A2 (en) 2009-03-31 2010-10-31 Institut Ruđer Bošković Adamantane bisurea derivates, method of their preparation and application in anion sensing
US20200079786A1 (en) * 2015-07-28 2020-03-12 Universitat De Barcelona Analogs of adamantylureas as soluble epoxide hydrolase inhibitors

Also Published As

Publication number Publication date
SE325024B (en) 1970-06-22
ES333485A1 (en) 1967-12-01
NL6616214A (en) 1967-05-19
DE1246722B (en) 1967-08-10
CH456570A (en) 1968-07-31
FR1504098A (en) 1967-12-01
ES333486A1 (en) 1968-01-01
BE689823A (en) 1967-05-17
FR6433M (en) 1968-11-04
ES333487A1 (en) 1967-12-01
AT267543B (en) 1969-01-10
AT267540B (en) 1969-01-10
GB1125559A (en) 1968-08-28
NO119270B (en) 1970-04-27

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