ES305661A1 - Procedure for the production of fenilciclopropan derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the production of fenilciclopropan derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES305661A1
ES305661A1 ES0305661A ES305661A ES305661A1 ES 305661 A1 ES305661 A1 ES 305661A1 ES 0305661 A ES0305661 A ES 0305661A ES 305661 A ES305661 A ES 305661A ES 305661 A1 ES305661 A1 ES 305661A1
Authority
ES
Spain
Prior art keywords
formula
translation
derivatives
production
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0305661A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitefin Holding SA
Original Assignee
Whitefin Holding SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitefin Holding SA filed Critical Whitefin Holding SA
Publication of ES305661A1 publication Critical patent/ES305661A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Process for the production of phenylcyclopropane derivatives, of the formula ** (See formula) ** where X it C R is hydrogen, hydroxyl, halogen, nitro, amino or a lower alkoxy radical, R1 is a straight or branched alkyl radical containing at least 2 carbon atoms, or a cycloalkyl, hydroxyalkyl, arylalkyl or aryl-cycloalkyl-alkyl radical and R2 is hydrogen or a straight or branched alkyl radical, or a lower hydroxyalkyl radical, or R1 and R2 together with the nitrogen to which they are bound, form a heterocyclic ring, characterized by reacting a compound of the formula ** (See formula) ** where R is as defined above and Z is chlorine, bromine or a methoxy or ethoxy radical, with an amine of the formula NHR1R2 where R1 and R2 are as defined above. (Machine-translation by Google Translate, not legally binding)
ES0305661A 1963-11-05 1964-11-04 Procedure for the production of fenilciclopropan derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES305661A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43626/63A GB1086191A (en) 1963-11-05 1963-11-05 Phenylcyclopropane derivatives

Publications (1)

Publication Number Publication Date
ES305661A1 true ES305661A1 (en) 1965-05-01

Family

ID=10429612

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0305661A Expired ES305661A1 (en) 1963-11-05 1964-11-04 Procedure for the production of fenilciclopropan derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (15)

Country Link
JP (2) JPS4821102B1 (en)
AT (3) AT266812B (en)
BE (1) BE655245A (en)
BR (1) BR6464004D0 (en)
CH (1) CH482648A (en)
DE (1) DE1518207B1 (en)
DK (1) DK127726B (en)
ES (1) ES305661A1 (en)
FI (1) FI43069B (en)
FR (4) FR4554M (en)
GB (2) GB1086191A (en)
IL (1) IL22302A (en)
LU (1) LU47291A1 (en)
NL (3) NL6412766A (en)
SE (1) SE317669B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4103030A (en) * 1974-12-11 1978-07-25 Sumitomo Chemical Company, Limited Novel cyclopropylmethylamine derivatives
US4202902A (en) * 1979-03-05 1980-05-13 Shell Oil Company Lipogenesis control by cyclopropane-carboxylic acids, esters and amides
GB2170197B (en) * 1985-01-17 1988-08-24 Ici Plc Tertiary amine compounds
EP0188887B1 (en) * 1985-01-17 1991-05-02 Imperial Chemical Industries Plc Tertiary amine compounds
GB8617377D0 (en) * 1986-07-16 1986-08-20 Ici Plc Tertiary amine compounds
AU8101191A (en) * 1990-07-18 1992-02-18 Sandoz Ltd. 2-cyclopropylacetic acid derivatives
CN101160285A (en) * 2005-03-17 2008-04-09 辉瑞大药厂 Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists
WO2007025144A1 (en) * 2005-08-24 2007-03-01 University Of Illinois - Chicago 5-ht2c receptor agonists as anorectic agents
US9108948B2 (en) 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
CN103382174A (en) 2006-06-23 2013-11-06 雅培制药有限公司 Cyclopropyl amine derivatives as histamin h3 receptor modulators
PT2195293E (en) 2007-08-22 2014-01-21 Astrazeneca Ab Cycloptopyl amide derivatives
TW201039825A (en) 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
RU2012136148A (en) 2010-02-18 2014-03-27 Астразенека Аб NEW CRYSTAL FORM OF THE CYCLOPROPYLBENZAMIDE DERIVATIVE
WO2012037258A1 (en) 2010-09-16 2012-03-22 Abbott Laboratories Processes for preparing 1,2-substituted cyclopropyl derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050559A (en) * 1962-08-21 Substituted phenylcyclopropylamjnes
US3081336A (en) * 1963-03-12 Carbamates
US2997422A (en) * 1959-01-09 1961-08-22 Smith Kline French Lab Monoamine oxidase inhibition
US3106578A (en) * 1960-09-16 1963-10-08 Smith Kline French Lab Nu-phenethyl-2-phenylcyclopropylamine derivatives
US3079403A (en) * 1960-09-19 1963-02-26 Smith Kline French Lab Process for preparing amines

Also Published As

Publication number Publication date
FR4217M (en) 1966-06-13
DE1518207B1 (en) 1971-07-01
AT273066B (en) 1969-07-25
GB1086191A (en) 1967-10-04
FR4555M (en) 1966-11-02
DK127726B (en) 1973-12-24
NL6412766A (en) 1965-05-06
JPS4821102B1 (en) 1973-06-26
GB1086192A (en) 1967-10-04
AT266812B (en) 1968-12-10
SE317669B (en) 1969-11-24
NL128365C (en)
JPS507598B1 (en) 1975-03-27
BR6464004D0 (en) 1973-08-09
FI43069B (en) 1970-10-01
FR4554M (en) 1966-11-02
BE655245A (en) 1965-05-04
FR4282M (en) 1966-07-11
AT269832B (en) 1969-04-10
NL6901128A (en) 1969-04-25
IL22302A (en) 1968-10-24
LU47291A1 (en) 1965-11-05
CH482648A (en) 1969-12-15

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