ES360031A1 - Procedure for the preparation of 1,2,4-oxadiazoles isomeros. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 1,2,4-oxadiazoles isomeros. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES360031A1 ES360031A1 ES360031A ES360031A ES360031A1 ES 360031 A1 ES360031 A1 ES 360031A1 ES 360031 A ES360031 A ES 360031A ES 360031 A ES360031 A ES 360031A ES 360031 A1 ES360031 A1 ES 360031A1
- Authority
- ES
- Spain
- Prior art keywords
- oxadiazoles
- translation
- procedure
- preparation
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005071 1,2,4-oxadiazoles Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Procedure for the preparation of 1,2,4-oxadiazoles isomers, which respond to the general formulas, **(See formula)** where A represents a linear or branched alkylene group containing from 2 to 6 carbon atoms; R1 and R2 are identical or different alkyl groups containing from 1 to 6 straight or branched chain carbon atoms or are linked together to form a heterocyclic radical with the nitrogen atoms, which may eventually contain a second heteroatom and be mono- or polysubstituted by methyl or ethyl moieties; R3, R4, R5, R7 each represent a hydrogen or halogen atom or a lower alkyl group or a lower alkoxy group, it being necessary that at least one of these five substituents be different from a hydrogen atom, characterized in that is reacted with a primary-tertiary amine **(See formula)** with a compound of formula III, **(See formula)** wherein X represents a substituent chosen from the group consisting of halogen atoms and -SCH3 in the presence of a hydrohalic acid acceptor. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR127496 | 1967-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES360031A1 true ES360031A1 (en) | 1970-06-16 |
Family
ID=8641459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES360031A Expired ES360031A1 (en) | 1967-11-09 | 1968-11-09 | Procedure for the preparation of 1,2,4-oxadiazoles isomeros. (Machine-translation by Google Translate, not legally binding) |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE722657A (en) |
| ES (1) | ES360031A1 (en) |
| FR (2) | FR1575544A (en) |
| NL (1) | NL6815378A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE852T1 (en) * | 1978-05-24 | 1982-04-15 | Imperial Chemical Industries Plc | ANTI-SECRETION OXADIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US5124455A (en) * | 1990-08-08 | 1992-06-23 | American Home Products Corporation | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents |
-
1967
- 1967-11-09 FR FR127496A patent/FR1575544A/fr not_active Expired
-
1968
- 1968-02-07 FR FR138995A patent/FR6972M/fr not_active Expired
- 1968-10-21 BE BE722657D patent/BE722657A/xx unknown
- 1968-10-28 NL NL6815378A patent/NL6815378A/xx unknown
- 1968-11-09 ES ES360031A patent/ES360031A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE722657A (en) | 1969-04-21 |
| NL6815378A (en) | 1969-05-13 |
| FR6972M (en) | 1969-05-19 |
| FR1575544A (en) | 1969-07-25 |
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