ES333485A1 - Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES333485A1
ES333485A1 ES0333485A ES333485A ES333485A1 ES 333485 A1 ES333485 A1 ES 333485A1 ES 0333485 A ES0333485 A ES 0333485A ES 333485 A ES333485 A ES 333485A ES 333485 A1 ES333485 A1 ES 333485A1
Authority
ES
Spain
Prior art keywords
formula
group
general formula
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0333485A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES333485A1 publication Critical patent/ES333485A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for the preparation of new substituted urea derivatives of the general formula ** (See formula) ** in which X means the methylene or ethylenic group, oxygen, the imino group or an alkylimino alkanoylimino lower group, And it means oxygen or sulfur, R1, R2 and R5 mean hydrogen or a lower alkyl group, R3 and R4 mean hydrogen, halogen up to the atomic number 35, the trifluoromethyl group or lower alkyl, alkoxy or alkanoyl groups, and n is 0 or 1, characterized in that an amine of the general formula II is reacted, ** (See formula) ** in which R2, R3 and R4 have the significance indicated under formula I, with an isocyanate or isothiocyanate of the general formula III ** (See formula) ** or with a functional derivative suitable for reaction of a carbamic or thiocarbamic acid of the general formula IV ** (See formula) ** in which X 'has the significance indicated under formula I for X excluding the imino group and Y, R1, R5 and n have the indicated significance, and if desired a lower alkanoyl radical that is found in X 'is split by hydrolysis. (Machine-translation by Google Translate, not legally binding)
ES0333485A 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES333485A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1590965A CH456570A (en) 1965-11-18 1965-11-18 Process for the production of new substituted urea derivatives

Publications (1)

Publication Number Publication Date
ES333485A1 true ES333485A1 (en) 1967-12-01

Family

ID=4412947

Family Applications (4)

Application Number Title Priority Date Filing Date
ES333486A Expired ES333486A1 (en) 1965-11-18 1966-11-17 Novel urea derivatives and their production
ES0333484A Expired ES333484A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES0333485A Expired ES333485A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
ES0333487A Expired ES333487A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES333486A Expired ES333486A1 (en) 1965-11-18 1966-11-17 Novel urea derivatives and their production
ES0333484A Expired ES333484A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES0333487A Expired ES333487A1 (en) 1965-11-18 1966-11-17 Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (10)

Country Link
AT (2) AT267540B (en)
BE (1) BE689823A (en)
CH (1) CH456570A (en)
DE (1) DE1246722B (en)
ES (4) ES333486A1 (en)
FR (2) FR1504098A (en)
GB (1) GB1125559A (en)
NL (1) NL6616214A (en)
NO (1) NO119270B (en)
SE (1) SE325024B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3621100A (en) * 1965-11-18 1971-11-16 Geigy Chem Corp Composition and method for producing a tuberculostatic effect
US3615941A (en) * 1968-05-07 1971-10-26 Hitachi Ltd Method for manufacturing semiconductor device with passivation film
BE758165A (en) * 1969-10-28 1971-04-28 Cilag Chemie ADAMANTYLURIDES AND METHODS FOR PREPARING THEM
JPH0193569A (en) * 1987-07-02 1989-04-12 Warner Lambert Co N-((2,6-disubstituted)phenyl)urea and carbamate inhibitor of acyl coa-cholesterol acyltransferase
ATE460405T1 (en) 2003-07-24 2010-03-15 Merck Sharp & Dohme ANTIBIOTIC COMPOUND
HRP20090186A2 (en) 2009-03-31 2010-10-31 Institut Ruđer Bošković Adamantane bisurea derivates, method of their preparation and application in anion sensing
WO2017017048A1 (en) * 2015-07-28 2017-02-02 Universitat De Barcelona Analogs of adamantylureas as soluble epoxide hydrolase inhibitors

Also Published As

Publication number Publication date
DE1246722B (en) 1967-08-10
SE325024B (en) 1970-06-22
NL6616214A (en) 1967-05-19
FR1504098A (en) 1967-12-01
AT267543B (en) 1969-01-10
AT267540B (en) 1969-01-10
NO119270B (en) 1970-04-27
ES333486A1 (en) 1968-01-01
ES333484A1 (en) 1967-12-01
CH456570A (en) 1968-07-31
ES333487A1 (en) 1967-12-01
FR6433M (en) 1968-11-04
GB1125559A (en) 1968-08-28
BE689823A (en) 1967-05-17

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