ES324892A1 - Procedure for the preparation of new derivatives of acridane. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of new acridane derivatives, of the general formula I, ** (See formula) ** in which R1 means a lower alkyl radical, R 2 signifies hydrogen, a lower alkyl radical or together with R 1 signifies a polymethylene radical, R3 and R4 mean independently, hydrogen, halogen atoms up to atomic number 35, trifluoromethyl radicals or alkyl or lower alkoxy radicals, R5 means the phenyl radical, or a biphenyl or phenoxyphenyl radical, whose benzene nuclei in any case, may each contain, at most, three substituents of the group consisting of halogen atoms, trifluoromethyl radicals, nitro groups, amino groups and radicals lower alkyls, alkoxy, alkylamino, dialkylamino and alkanoylamino, or means a pyridyl radical optionally substituted by halogen atoms, alkyl or lower alkoxy radicals, R6 means an inner alkyl radical and A means an alkylene radical with 2-6 carbon atoms, and its addition salts with inorganic and organic acids, characterized in that a compound of the general formula II ** (See formula) ** in which R1, R2, R3, R4, R5, R6 and A have the significance indicated above, the mixture is heated until the equimolar dose of carbon dioxide is split and, if desired, the compound obtained in the general formula I is transformed with an inorganic or organic acid into an addition salt. (Machine-translation by Google Translate, not legally binding)