ES2983452T3 - Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente - Google Patents

Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente Download PDF

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Publication number
ES2983452T3
ES2983452T3 ES21180905T ES21180905T ES2983452T3 ES 2983452 T3 ES2983452 T3 ES 2983452T3 ES 21180905 T ES21180905 T ES 21180905T ES 21180905 T ES21180905 T ES 21180905T ES 2983452 T3 ES2983452 T3 ES 2983452T3
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ES
Spain
Prior art keywords
sensor
areas
exposed
electrode areas
reference electrode
Prior art date
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Active
Application number
ES21180905T
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English (en)
Spanish (es)
Inventor
Buck Harvey
Georgeta Lica
Karl-Heinz Koelker
Ewald Rieger
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/2415—Measuring direct current [DC] or slowly varying biopotentials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/263—Bioelectric electrodes therefor characterised by the electrode materials
    • A61B5/265—Bioelectric electrodes therefor characterised by the electrode materials containing silver or silver chloride
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A61B2560/0468—Built-in electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/043—Arrangements of multiple sensors of the same type in a linear array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/301—Reference electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
ES21180905T 2010-10-08 2011-10-01 Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente Active ES2983452T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/901,078 US9084570B2 (en) 2010-10-08 2010-10-08 Electrochemical sensor having symmetrically distributed analyte sensitive areas

Publications (1)

Publication Number Publication Date
ES2983452T3 true ES2983452T3 (es) 2024-10-23

Family

ID=44799976

Family Applications (2)

Application Number Title Priority Date Filing Date
ES21180905T Active ES2983452T3 (es) 2010-10-08 2011-10-01 Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente
ES11769782T Active ES2906449T3 (es) 2010-10-08 2011-10-01 Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES11769782T Active ES2906449T3 (es) 2010-10-08 2011-10-01 Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente

Country Status (10)

Country Link
US (3) US9084570B2 (https=)
EP (2) EP2624756B1 (https=)
JP (1) JP6104805B2 (https=)
KR (1) KR20130057477A (https=)
CN (1) CN103140170B (https=)
AU (1) AU2011313631A1 (https=)
ES (2) ES2983452T3 (https=)
HU (2) HUE057419T2 (https=)
MX (1) MX2013003471A (https=)
WO (1) WO2012045425A1 (https=)

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US9535027B2 (en) * 2012-07-25 2017-01-03 Abbott Diabetes Care Inc. Analyte sensors and methods of using same
CN104055526A (zh) * 2013-12-05 2014-09-24 庞德兴 一种无源微创皮下生化参数检测芯片
KR102007585B1 (ko) * 2014-11-03 2019-08-05 에프. 호프만-라 로슈 아게 전기화학 테스트 엘리먼트들에 대한 전극 배열들 및 그의 이용 방법들
KR20190091569A (ko) 2014-12-19 2019-08-06 에프. 호프만-라 로슈 아게 적어도 하나의 분석물을 전기 화학적으로 검출하기 위한 테스트 엘리먼트
HUE055998T2 (hu) * 2016-12-22 2022-01-28 Sanvita Medical Llc Folyamatos glükóz ellenõrzõ rendszer és eljárás
WO2018229581A1 (en) 2017-06-11 2018-12-20 Kenzen Ag Chip-based multi-channel electrochemical transducer and method of use thereof
ES3023573T3 (en) * 2017-09-18 2025-06-02 Hoffmann La Roche Electrochemical sensor for detecting at least one analyte
ES2831076T3 (es) * 2017-11-08 2021-06-07 Hoffmann La Roche Sensor para detectar un analito en un líquido corporal y procedimiento de fabricación del mismo
US12076145B2 (en) * 2018-04-19 2024-09-03 Abbott Diabetes Care Inc. Lactate sensors and associated methods
CN109959679B (zh) * 2019-03-08 2020-06-05 浙江大学 一种用于3d肿瘤细胞迁移实时监测的垂直多电极阻抗传感器及制备方法
JP7264465B2 (ja) * 2019-06-24 2023-04-25 テクノグローバル株式会社 電極構造体、電気化学測定装置、及び電気化学測定方法
EP3798628B1 (en) 2019-09-27 2025-04-16 Heraeus Medevio GmbH & Co. KG Method for manufacturing an electrochemical sensor
KR102296827B1 (ko) 2019-11-08 2021-09-01 재단법인대구경북과학기술원 삽입형 바이오센서
EP4070088A1 (en) * 2019-12-06 2022-10-12 Innovative Water Care, LLC Amperometric sensor for measuring free chlorine with reference electrode having a gold electrode surface composed of a string of electrically connected, spaced apart surface parts
US11877847B2 (en) * 2020-01-31 2024-01-23 Taiwan Semiconductor Manufacturing Company, Ltd. Biosensor apparatus
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EP4710854A3 (en) 2021-05-06 2026-03-25 Roche Diabetes Care GmbH Analyte sensor and a method for its producing
HUE070450T2 (hu) 2021-08-18 2025-06-28 Hoffmann La Roche Analitszenzor és eljárás annak elõállítására
CN113740400B (zh) * 2021-08-18 2023-10-24 淮阴工学院 带有对称参比电极的封闭式双极电极阵列的分析检测装置
CN114184661B (zh) * 2021-11-26 2025-03-14 北京大学 一种电化学传感器及其制造方法
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Also Published As

Publication number Publication date
AU2011313631A1 (en) 2013-02-07
US10349878B2 (en) 2019-07-16
US9757060B2 (en) 2017-09-12
EP2624756A1 (en) 2013-08-14
ES2906449T3 (es) 2022-04-18
KR20130057477A (ko) 2013-05-31
EP2624756B1 (en) 2021-12-15
HK1185780A1 (zh) 2014-02-28
JP6104805B2 (ja) 2017-03-29
HUE067577T2 (hu) 2024-10-28
CN103140170B (zh) 2016-03-16
HUE057419T2 (hu) 2022-05-28
US20170367628A1 (en) 2017-12-28
CN103140170A (zh) 2013-06-05
JP2013543405A (ja) 2013-12-05
MX2013003471A (es) 2013-05-31
EP3926339B1 (en) 2024-05-15
US9084570B2 (en) 2015-07-21
EP3926339A1 (en) 2021-12-22
WO2012045425A1 (en) 2012-04-12
US20150320345A1 (en) 2015-11-12
EP3926339C0 (en) 2024-05-15
US20120088993A1 (en) 2012-04-12

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