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Organon NV
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Organon NV
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Publication of ES297535A1publicationCriticalpatent/ES297535A1/en
A process for the preparation of 16-methylene steroids characterized in that new compounds of the general formula are prepared: ** (See formula) ** wherein R1 = H2 or O, R2 = H or an acyl group, R3 = H or a saturated or unsaturated alkyl group with 1 to 4 carbon atoms, starting from a compound of the general formula: ** (See formula) ** where ring A has one of the following configurations ** (See formula) ** and in that the 3-position substituent, if any, in the starting products, can be temporarily protected by converting the starting product by a known method into a delta4-3-keto-steroid, or a delta4-3-dexoxo-steroid , if necessary, and introducing the substituents in position 17, as indicated in the formula of the final products, by reduction of the 17-keto group, or by an alcohol reaction followed, if desired, by esterification of group 17- hydroxyl, in which the reaction steps can be carried out in any order. (Machine-translation by Google Translate, not legally binding)
ES297535A1963-03-131964-03-12A procedure for the preparation of 16-methylene-steroids (Machine-translation by Google Translate, not legally binding)
ExpiredES297535A1
(en)
A procedure for preparation of the 3.17 epsilon-dihydroxy (delta2'3 dihydro) (4'5'-16,17) -isoxazolino 13-z gona 1, 3,5 (10) -triene. (Machine-translation by Google Translate, not legally binding)