ES2972783T3 - Tratamiento de las neoplasias malignas hematológicas - Google Patents
Tratamiento de las neoplasias malignas hematológicasInfo
- Publication number
- ES2972783T3 ES2972783T3 ES18743104T ES18743104T ES2972783T3 ES 2972783 T3 ES2972783 T3 ES 2972783T3 ES 18743104 T ES18743104 T ES 18743104T ES 18743104 T ES18743104 T ES 18743104T ES 2972783 T3 ES2972783 T3 ES 2972783T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- hematological malignancies
- hematological
- malignancies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000002250 Hematologic Neoplasms Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6006—Cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10041—Use of virus, viral particle or viral elements as a vector
- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL2019156A NL2019156B1 (en) | 2017-06-30 | 2017-06-30 | Treatment of haematological malignancies |
NL2020602 | 2018-03-16 | ||
PCT/NL2018/050421 WO2019004831A1 (en) | 2017-06-30 | 2018-06-28 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2972783T3 true ES2972783T3 (es) | 2024-06-17 |
Family
ID=62976114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES18743104T Active ES2972783T3 (es) | 2017-06-30 | 2018-06-28 | Tratamiento de las neoplasias malignas hematológicas |
Country Status (8)
Country | Link |
---|---|
US (1) | US11352389B2 (es) |
EP (2) | EP3645560B1 (es) |
JP (2) | JP2020530274A (es) |
KR (1) | KR20200023311A (es) |
CN (1) | CN111032686B (es) |
CA (1) | CA3067772A1 (es) |
ES (1) | ES2972783T3 (es) |
WO (1) | WO2019004831A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11202111865UA (en) * | 2019-05-01 | 2021-11-29 | Pact Pharma Inc | Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy |
IL296241A (en) | 2020-03-10 | 2022-11-01 | Massachusetts Inst Technology | Compositions and methods for immunotherapy for npm1c-positive cancer |
CN113082211A (zh) * | 2021-04-14 | 2021-07-09 | 南方医科大学珠江医院 | 一种治疗npm1突变急性髓系白血病的药物组合物及其应用 |
WO2023219510A1 (en) * | 2022-05-13 | 2023-11-16 | Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) | Treatment of haematological malignancies |
EP4368189A1 (en) * | 2022-11-09 | 2024-05-15 | Eberhard Karls Universität Tübingen, Medizinische Fakultät | Peptides and combinations of peptides for use in immunotherapy against acute myeloid leukemia (aml) and other hematological neoplasms |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6750325B1 (en) | 1989-12-21 | 2004-06-15 | Celltech R&D Limited | CD3 specific recombinant antibody |
GB9206422D0 (en) | 1992-03-24 | 1992-05-06 | Bolt Sarah L | Antibody preparation |
US8784821B1 (en) | 2003-05-31 | 2014-07-22 | Amgen Research (Munich) Gmbh | Human-anti-human cd3 binding molecules |
ITRM20040534A1 (it) * | 2004-10-29 | 2005-01-29 | Brunangelo Falini | Mutanti della proteina nucleofosmina (npm), sequenze geniche corrispondenti e relativi usi. |
GB0511124D0 (en) * | 2005-06-01 | 2005-07-06 | Avidex Ltd | High affinity melan-a t cell receptors |
WO2009061182A1 (en) * | 2007-11-05 | 2009-05-14 | Leiden University Medical Center | Hla class ii pi4k2b mhags and application thereof |
BR112013006718B1 (pt) * | 2010-09-20 | 2021-12-07 | Tron - Translationale Onkologie An Der Universitätsmedizin Der Johannes Gutenberguniversität Mainz Gemeinnutzige Gmbh | Receptor de células t com especificidade para ny-eso-1, composição farmacêutica compreendendo o mesmo e uso do mesmo |
CN102775495A (zh) * | 2011-05-12 | 2012-11-14 | 北京大学第一医院 | 多肽混合物、t细胞疫苗及其应用 |
WO2015163778A1 (en) * | 2014-04-22 | 2015-10-29 | Chudakov Dmitry Mikhajlovich | Method to identify hot spot pcr and sequencing errors in highthroughput sequencing data |
JP6712261B2 (ja) * | 2014-08-04 | 2020-06-24 | フレッド ハッチンソン キャンサー リサーチ センター | Wt−1に特異的なt細胞免疫治療 |
WO2016071758A1 (en) | 2014-11-03 | 2016-05-12 | Leiden University Medical Center | T cell receptors directed against bob1 and uses thereof |
AU2016264623B2 (en) * | 2015-05-20 | 2022-06-30 | Dana-Farber Cancer Institute, Inc. | Shared neoantigens |
-
2018
- 2018-06-28 ES ES18743104T patent/ES2972783T3/es active Active
- 2018-06-28 CA CA3067772A patent/CA3067772A1/en active Pending
- 2018-06-28 KR KR1020197038722A patent/KR20200023311A/ko not_active Application Discontinuation
- 2018-06-28 EP EP18743104.4A patent/EP3645560B1/en active Active
- 2018-06-28 CN CN201880056360.XA patent/CN111032686B/zh active Active
- 2018-06-28 JP JP2019572562A patent/JP2020530274A/ja active Pending
- 2018-06-28 EP EP23209249.4A patent/EP4327819A3/en active Pending
- 2018-06-28 WO PCT/NL2018/050421 patent/WO2019004831A1/en active Application Filing
- 2018-06-28 US US16/627,230 patent/US11352389B2/en active Active
-
2023
- 2023-06-06 JP JP2023093023A patent/JP2023116601A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20200123200A1 (en) | 2020-04-23 |
EP3645560B1 (en) | 2023-12-20 |
CA3067772A1 (en) | 2019-01-03 |
EP4327819A2 (en) | 2024-02-28 |
KR20200023311A (ko) | 2020-03-04 |
US11352389B2 (en) | 2022-06-07 |
EP3645560A1 (en) | 2020-05-06 |
WO2019004831A8 (en) | 2022-10-13 |
JP2023116601A (ja) | 2023-08-22 |
JP2020530274A (ja) | 2020-10-22 |
WO2019004831A1 (en) | 2019-01-03 |
CN111032686A (zh) | 2020-04-17 |
EP4327819A3 (en) | 2024-05-29 |
CN111032686B (zh) | 2024-05-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ECSP17029371A (es) | Dihidropirrolopiridinas inhibidoras de ror-gamma | |
IT201700081018A1 (it) | Trattamento di segnali elettrofisiologici | |
MA41997A (fr) | Combinaisons de cannabinoïdes et de n-acyléthanolamines | |
ES2972783T3 (es) | Tratamiento de las neoplasias malignas hematológicas | |
MA41449A (fr) | Polythérapies pour le traitement de cancers | |
MA46180A (fr) | Analogues de l'amyline | |
DK3458052T3 (da) | Kombinationsbehandling af cancer | |
DK3283210T3 (da) | Fremgangsmåde | |
MA47408A (fr) | Traitement du cancer | |
DK2897382T3 (da) | Forbedring af binaural kilde | |
FR3037803B1 (fr) | Implant de substitution du sternum | |
DK3073409T3 (da) | Maskering af forskellige indholdstyper | |
DK3576740T3 (da) | Cancerbehandling | |
FR3022129B1 (fr) | Baignoire de puericulture | |
ES1137506Y (es) | Helice reductora de perdidas | |
FR3024647B1 (fr) | Transat de puericulture | |
DK3275315T3 (da) | Fileteringsindretning | |
KR20180084983A (ko) | 암의 치료를 위한 피리미도-피리미다지논의 용도 | |
MA42130A (fr) | Combinaisons d'opioïdes et de n-acyléthanolamines | |
DK3302499T3 (da) | Behandling af mitokondrielle sygdomme | |
DK3285588T3 (da) | Fremgangsmåde | |
DK3182980T3 (da) | Behandling af glykosyleringsmangelsygdomme | |
FI20145980A (fi) | Kompleksisen sulfidirikasteen käsittely | |
FR3035458B1 (fr) | Capuchon de fixation rotule | |
FI20155387A (fi) | Sterolien tuottaminen |