ES2970868T3 - Métodos y composiciones para la detección y diagnóstico de enfermedad renal y enfermedad periodontal - Google Patents

Métodos y composiciones para la detección y diagnóstico de enfermedad renal y enfermedad periodontal Download PDF

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Publication number
ES2970868T3
ES2970868T3 ES17713512T ES17713512T ES2970868T3 ES 2970868 T3 ES2970868 T3 ES 2970868T3 ES 17713512 T ES17713512 T ES 17713512T ES 17713512 T ES17713512 T ES 17713512T ES 2970868 T3 ES2970868 T3 ES 2970868T3
Authority
ES
Spain
Prior art keywords
polypeptides
cystatin
antibodies
seq
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17713512T
Other languages
English (en)
Spanish (es)
Inventor
Mahalakshmi Yerramilli
Giosi Farace
John Quinn
Murthy Yerramilli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Idexx Laboratories Inc
Original Assignee
Idexx Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idexx Laboratories Inc filed Critical Idexx Laboratories Inc
Application granted granted Critical
Publication of ES2970868T3 publication Critical patent/ES2970868T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/348—Urinary tract infections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
ES17713512T 2016-03-02 2017-03-02 Métodos y composiciones para la detección y diagnóstico de enfermedad renal y enfermedad periodontal Active ES2970868T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662302299P 2016-03-02 2016-03-02
PCT/US2017/020377 WO2017151871A1 (en) 2016-03-02 2017-03-02 Methods and compositions for the detection and diagnosis of renal disease and periodontal disease

Publications (1)

Publication Number Publication Date
ES2970868T3 true ES2970868T3 (es) 2024-05-31

Family

ID=58410448

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17713512T Active ES2970868T3 (es) 2016-03-02 2017-03-02 Métodos y composiciones para la detección y diagnóstico de enfermedad renal y enfermedad periodontal

Country Status (16)

Country Link
US (3) US10725052B2 (enExample)
EP (2) EP4299586A3 (enExample)
JP (3) JP7187317B2 (enExample)
KR (2) KR102424496B1 (enExample)
CN (1) CN108700600B (enExample)
AR (2) AR107786A1 (enExample)
AU (1) AU2017225758B2 (enExample)
BR (1) BR112018067292A2 (enExample)
CA (1) CA3016163A1 (enExample)
DK (1) DK3423838T5 (enExample)
ES (1) ES2970868T3 (enExample)
MX (2) MX2018010536A (enExample)
NZ (1) NZ745263A (enExample)
TW (1) TWI822655B (enExample)
WO (1) WO2017151871A1 (enExample)
ZA (1) ZA201806418B (enExample)

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KR102424496B1 (ko) * 2016-03-02 2022-07-25 아이덱스 래보러토리즈, 인코포레이티드 신장 질환 및 치주 질환의 검출 및 진단을 위한 방법 및 조성물
AU2018313853A1 (en) 2017-08-08 2020-01-02 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
JP7207585B2 (ja) * 2017-09-01 2023-01-18 株式会社三洋物産 遊技機
CN110938130B (zh) * 2019-11-08 2021-07-09 上海交通大学 一种生物活性多肽rvfqplphenkpltl及其制备方法和应用
TWI902784B (zh) 2020-04-17 2025-11-01 美商英代斯實驗公司 螢光淬滅免疫分析
US11175293B1 (en) 2021-01-04 2021-11-16 University Of Utah Research Foundation Rapid assay for detection of SARS-CoV-2 antibodies
JP2021079146A (ja) * 2021-02-22 2021-05-27 株式会社三洋物産 遊技機
JP7315071B2 (ja) * 2021-03-03 2023-07-26 株式会社三洋物産 遊技機
AU2023213987A1 (en) * 2022-01-26 2024-09-05 Idexx Laboratories, Inc. Methods and compositions for differentiating progressive chronic kidney disease from stable chronic kidney disease
TWI882593B (zh) * 2022-12-23 2025-05-01 高雄醫學大學 上泌尿道結石風險評估模型建立方法

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GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
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DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
US5726010A (en) 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
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US20070015146A1 (en) 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
NL1020962C2 (nl) 2002-06-28 2003-12-30 Tno Therapie en prognose/monitoring bij sepsis en septische shock.
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WO2006083986A2 (en) * 2005-02-01 2006-08-10 Government Of The U.S.A, As Represented By The Secretary Department Of Health & Human Services Biomarkers for tissue status
US8383357B2 (en) 2005-03-16 2013-02-26 OSI Pharmaceuticals, LLC Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
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KR101222437B1 (ko) * 2010-03-17 2013-01-15 경북대학교 산학협력단 바이오마커
EP3845904A1 (en) * 2010-06-03 2021-07-07 Idexx Laboratories, Inc. Markers for renal disease
CN101937000A (zh) * 2010-08-05 2011-01-05 北京倍爱康生物技术有限公司 一种人胱抑素c的磁微粒分离化学发光免疫分析检测方法
KR102424496B1 (ko) 2016-03-02 2022-07-25 아이덱스 래보러토리즈, 인코포레이티드 신장 질환 및 치주 질환의 검출 및 진단을 위한 방법 및 조성물

Also Published As

Publication number Publication date
CN108700600B (zh) 2022-06-03
KR102424496B1 (ko) 2022-07-25
JP7187317B2 (ja) 2022-12-12
US10725052B2 (en) 2020-07-28
BR112018067292A2 (pt) 2019-01-02
NZ745263A (en) 2022-07-01
CN108700600A (zh) 2018-10-23
MX2018010536A (es) 2018-11-09
JP2024028816A (ja) 2024-03-05
US20200400683A1 (en) 2020-12-24
AR107786A1 (es) 2018-06-06
KR20180114936A (ko) 2018-10-19
DK3423838T3 (da) 2024-02-05
KR102311590B1 (ko) 2021-10-12
EP4299586A2 (en) 2024-01-03
US20170269101A1 (en) 2017-09-21
DK3423838T5 (da) 2024-09-16
US20250341529A1 (en) 2025-11-06
EP3423838A1 (en) 2019-01-09
JP7598843B2 (ja) 2024-12-12
AU2017225758A1 (en) 2018-08-30
EP4299586A3 (en) 2024-04-03
TW201736850A (zh) 2017-10-16
EP3423838B1 (en) 2023-11-08
CA3016163A1 (en) 2017-09-08
TWI822655B (zh) 2023-11-21
US12385927B2 (en) 2025-08-12
JP2019508694A (ja) 2019-03-28
AR131922A2 (es) 2025-05-14
JP2022028790A (ja) 2022-02-16
JP7815199B2 (ja) 2026-02-17
ZA201806418B (en) 2019-07-31
MX2023012628A (es) 2023-11-08
WO2017151871A1 (en) 2017-09-08
AU2017225758B2 (en) 2023-03-16
KR20210127763A (ko) 2021-10-22

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