ES2969979T3 - Métodos para detectar enfermedad renal - Google Patents
Métodos para detectar enfermedad renal Download PDFInfo
- Publication number
- ES2969979T3 ES2969979T3 ES18196516T ES18196516T ES2969979T3 ES 2969979 T3 ES2969979 T3 ES 2969979T3 ES 18196516 T ES18196516 T ES 18196516T ES 18196516 T ES18196516 T ES 18196516T ES 2969979 T3 ES2969979 T3 ES 2969979T3
- Authority
- ES
- Spain
- Prior art keywords
- kidney disease
- methods
- disclosure
- kidney
- gfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 208000017169 kidney disease Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- HVPFXCBJHIIJGS-LURJTMIESA-N N(omega),N'(omega)-dimethyl-L-arginine Chemical compound CN\C(=N/C)NCCC[C@H](N)C(O)=O HVPFXCBJHIIJGS-LURJTMIESA-N 0.000 abstract 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- 230000024924 glomerular filtration Effects 0.000 abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 241000282326 Felis catus Species 0.000 abstract 1
- 206010062237 Renal impairment Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229940109239 creatinine Drugs 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000003907 kidney function Effects 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Bioinformatics & Computational Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La divulgación está dirigida a métodos y aparatos para la determinación, diagnóstico, progresión y pronóstico de la enfermedad renal y la mortalidad asociada con la enfermedad renal. La divulgación incluye un método para determinar la función renal, en particular estimar la tasa de filtración glomerular (TFG), en un animal. La TFG puede ser útil en el diagnóstico y tratamiento de enfermedades o disfunciones renales. En diversos aspectos, la divulgación se dirige al uso de dimetilarginina simétrica libre (SDMA) y creatinina en muestras de sangre de animales, en particular gatos y perros, para determinar la tasa de filtración glomerular y la enfermedad renal. (Traducción automática con Google Translate, sin valor legal)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361874011P | 2013-09-05 | 2013-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2969979T3 true ES2969979T3 (es) | 2024-05-23 |
Family
ID=52628954
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18196516T Active ES2969979T3 (es) | 2013-09-05 | 2014-09-05 | Métodos para detectar enfermedad renal |
| ES14842603T Active ES2746008T3 (es) | 2013-09-05 | 2014-09-05 | Métodos para detectar enfermedad renal |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14842603T Active ES2746008T3 (es) | 2013-09-05 | 2014-09-05 | Métodos para detectar enfermedad renal |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US11035861B2 (es) |
| EP (3) | EP3041576B1 (es) |
| JP (4) | JP6657096B2 (es) |
| KR (2) | KR102273028B1 (es) |
| CN (1) | CN105705202B (es) |
| AU (2) | AU2014315063B2 (es) |
| CA (2) | CA2923140C (es) |
| CY (1) | CY1123179T1 (es) |
| DK (1) | DK3041576T3 (es) |
| ES (2) | ES2969979T3 (es) |
| HR (1) | HRP20191569T1 (es) |
| HU (1) | HUE045723T2 (es) |
| LT (1) | LT3041576T (es) |
| MX (2) | MX2016002922A (es) |
| NZ (1) | NZ717554A (es) |
| PL (1) | PL3041576T3 (es) |
| PT (1) | PT3041576T (es) |
| RS (1) | RS59287B1 (es) |
| SI (1) | SI3041576T1 (es) |
| WO (1) | WO2015035155A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015035155A1 (en) | 2013-09-05 | 2015-03-12 | Idexx Laboratories, Inc. | Methods for detecting renal disease |
| KR102492243B1 (ko) | 2015-02-20 | 2023-01-25 | 아이덱스 래보러토리즈, 인코포레이티드 | 배경 신호에 대한 보상에 의한 균질 면역검정 |
| WO2016176691A1 (en) * | 2015-04-30 | 2016-11-03 | Idexx Laboratories, Inc. | Methods for detecting renal disease |
| CA3063424A1 (en) | 2017-05-31 | 2018-12-06 | Mars, Incorporated | Methods of diagnosing and treating chronic kidney disease |
| CA3072427C (en) | 2017-08-08 | 2023-12-05 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
| KR20200073259A (ko) * | 2017-10-19 | 2020-06-23 | 아이덱스 래보러토리즈, 인코포레이티드 | 대칭 디메틸아르기닌의 검출 |
| US20210373031A1 (en) * | 2018-10-17 | 2021-12-02 | Kagami Inc. | Method for determining glomerular filtration ability |
| CN109545377B (zh) * | 2018-10-22 | 2021-11-23 | 中南大学湘雅三医院 | 获取肾小球滤过率的模型的建立方法 |
| US10745492B1 (en) * | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
| EP4025301A4 (en) * | 2019-09-05 | 2023-07-19 | The Regents of the University of California | NON-INVASIVE METHOD FOR QUANTIFYING KIDNEY FUNCTION AND FUNCTIONAL DECLINE |
| JP6993654B2 (ja) * | 2019-12-27 | 2022-02-15 | Kagami株式会社 | 腎機能を推定する方法及びシステム |
| CN112768073B (zh) * | 2021-01-15 | 2023-04-18 | 中山大学附属第三医院 | 一种肾小球滤过率估计模型的构建方法 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3134787A1 (de) * | 1981-09-02 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Creatinin-antikoerper |
| US4818703A (en) | 1985-10-23 | 1989-04-04 | Pizzolante John M | Stabilized alkaline picrate reagent for jaffe creatinine determination |
| EP0356160A3 (en) | 1988-08-24 | 1991-09-11 | The Board Of Trustees Of The Leland Stanford Junior University | Capillary device |
| US5726010A (en) | 1991-07-31 | 1998-03-10 | Idexx Laboratories, Inc. | Reversible flow chromatographic binding assay |
| US6455288B1 (en) | 1993-04-08 | 2002-09-24 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
| US5804452A (en) * | 1995-04-27 | 1998-09-08 | Quidel Corporation | One step urine creatinine assays |
| WO1998049199A1 (en) | 1997-05-01 | 1998-11-05 | Panorama Research, Inc. | Cardiovascular disease risk assessment |
| US6736957B1 (en) | 1997-10-16 | 2004-05-18 | Abbott Laboratories | Biosensor electrode mediators for regeneration of cofactors and process for using |
| US6358699B1 (en) | 1999-02-05 | 2002-03-19 | Cooke Pharma | Assay for asymmetrical NG, NG dimethyl-l-arginine |
| WO2001046221A1 (en) | 1999-12-22 | 2001-06-28 | The Research Foundation Of State University Of New York | Protein methylarginine-specific antibodies |
| WO2002004465A1 (en) | 2000-07-06 | 2002-01-17 | Fal Diagnostics | Methods and kits for the detection of arginine compounds |
| EP1301790B1 (en) * | 2000-07-12 | 2008-04-09 | Naser, Werner, Dr. | Direct assessment of analyte to reference molecule ratios |
| DE10040904A1 (de) | 2000-08-18 | 2002-02-28 | Boeger Rainer H | Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen |
| US7241856B2 (en) | 2003-06-02 | 2007-07-10 | Pentron Clinical Technologies Llc | Dental resins, dental composite materials, and method of manufacture thereof |
| JP4214271B2 (ja) | 2002-10-15 | 2009-01-28 | アークレイ株式会社 | クレアチニン測定用試験片 |
| US7501053B2 (en) | 2002-10-23 | 2009-03-10 | Abbott Laboratories | Biosensor having improved hematocrit and oxygen biases |
| WO2004046314A2 (en) | 2002-11-15 | 2004-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for detecting asymmetric dimethylarginine in a biological sample |
| US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
| ES2332218T3 (es) | 2004-11-04 | 2010-01-29 | Germediq Forschungs- Und Entwicklungsgesellschaft Mbh | Metodo para la determinacion de arginina, argininas metiladas y sus derivados. |
| US8725990B1 (en) | 2004-11-15 | 2014-05-13 | Nvidia Corporation | Configurable SIMD engine with high, low and mixed precision modes |
| WO2006078813A2 (en) | 2005-01-21 | 2006-07-27 | Biosite Incorporated | Arginine analogs, and methods for their synthesis and use |
| JP2007176872A (ja) | 2005-12-28 | 2007-07-12 | Sentan Seimei Kagaku Kenkyusho:Kk | アシンメトリックジメチルアルギニンを認識する抗体及びその製造方法並びに翻訳後修飾アミノ酸含有タンパク質の検出方法 |
| FR2919063B1 (fr) * | 2007-07-19 | 2009-10-02 | Biomerieux Sa | Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal. |
| EP2229452B1 (en) | 2007-12-05 | 2015-07-29 | King's College London | Method for aiding the diagnosis of a disorder |
| EP3808733A1 (en) * | 2008-08-07 | 2021-04-21 | IDEXX Laboratories, Inc. | Methods for detecting symmetrical demethylarginine |
| ES2499415T3 (es) * | 2009-06-02 | 2014-09-29 | Biocrates Life Sciences Ag | Nuevos biomarcadores para la evaluación de enfermedades renales |
| CN101587118B (zh) * | 2009-07-03 | 2012-09-12 | 长春迪瑞医疗科技股份有限公司 | 肌酐尿液分析试纸及制备方法 |
| CN101598727B (zh) * | 2009-07-09 | 2012-10-10 | 上海科华生物工程股份有限公司 | 定量测定人体血液尿素含量的干化学试纸 |
| CN101865911A (zh) * | 2010-03-16 | 2010-10-20 | 苏州市玮琪生物科技有限公司 | 一种尿肌酐定量检测卡 |
| WO2012065912A1 (de) | 2010-11-17 | 2012-05-24 | Karl-Heinz Kellner | Automatenfähiger immunoassay für biogene amine |
| JP2012112785A (ja) | 2010-11-24 | 2012-06-14 | Tohoku Univ | 透析膜の評価方法 |
| JP5925026B2 (ja) * | 2011-04-28 | 2016-05-25 | アークレイ株式会社 | クレアチニン測定用乾式試験片及びクレアチニン測定法 |
| US20140038203A1 (en) * | 2012-07-09 | 2014-02-06 | Musc Foundation For Research Development | Methods for detecting or predicting kidney disease |
| WO2015035155A1 (en) | 2013-09-05 | 2015-03-12 | Idexx Laboratories, Inc. | Methods for detecting renal disease |
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2014
- 2014-09-05 WO PCT/US2014/054278 patent/WO2015035155A1/en active Application Filing
- 2014-09-05 MX MX2016002922A patent/MX2016002922A/es unknown
- 2014-09-05 ES ES18196516T patent/ES2969979T3/es active Active
- 2014-09-05 NZ NZ717554A patent/NZ717554A/en unknown
- 2014-09-05 AU AU2014315063A patent/AU2014315063B2/en active Active
- 2014-09-05 LT LT14842603T patent/LT3041576T/lt unknown
- 2014-09-05 CA CA2923140A patent/CA2923140C/en active Active
- 2014-09-05 CN CN201480060296.4A patent/CN105705202B/zh active Active
- 2014-09-05 PL PL14842603T patent/PL3041576T3/pl unknown
- 2014-09-05 ES ES14842603T patent/ES2746008T3/es active Active
- 2014-09-05 EP EP14842603.4A patent/EP3041576B1/en active Active
- 2014-09-05 EP EP18196516.1A patent/EP3480600B1/en active Active
- 2014-09-05 JP JP2016540417A patent/JP6657096B2/ja active Active
- 2014-09-05 EP EP23207400.5A patent/EP4295907A3/en active Pending
- 2014-09-05 PT PT14842603T patent/PT3041576T/pt unknown
- 2014-09-05 SI SI201431344T patent/SI3041576T1/sl unknown
- 2014-09-05 RS RSP20191171 patent/RS59287B1/sr unknown
- 2014-09-05 KR KR1020167009015A patent/KR102273028B1/ko active IP Right Grant
- 2014-09-05 KR KR1020217020124A patent/KR102412431B1/ko active IP Right Grant
- 2014-09-05 DK DK14842603.4T patent/DK3041576T3/da active
- 2014-09-05 CA CA3213810A patent/CA3213810A1/en active Pending
- 2014-09-05 HU HUE14842603A patent/HUE045723T2/hu unknown
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2016
- 2016-03-04 US US15/061,327 patent/US11035861B2/en active Active
- 2016-03-04 MX MX2021006716A patent/MX2021006716A/es unknown
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2019
- 2019-08-30 HR HRP20191569 patent/HRP20191569T1/hr unknown
- 2019-09-12 CY CY20191100954T patent/CY1123179T1/el unknown
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2020
- 2020-02-05 JP JP2020017580A patent/JP2020073927A/ja active Pending
- 2020-10-16 AU AU2020256440A patent/AU2020256440B2/en active Active
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2021
- 2021-06-09 US US17/343,369 patent/US20220137059A1/en active Pending
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2022
- 2022-02-02 JP JP2022014586A patent/JP2022070879A/ja active Pending
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2023
- 2023-11-14 JP JP2023193309A patent/JP2024020376A/ja active Pending
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