ES2968301T3 - Liofilización por encima del colapso - Google Patents
Liofilización por encima del colapso Download PDFInfo
- Publication number
- ES2968301T3 ES2968301T3 ES19181153T ES19181153T ES2968301T3 ES 2968301 T3 ES2968301 T3 ES 2968301T3 ES 19181153 T ES19181153 T ES 19181153T ES 19181153 T ES19181153 T ES 19181153T ES 2968301 T3 ES2968301 T3 ES 2968301T3
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- temperature
- collapse
- freeze
- protein
- drying
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8642608P | 2008-08-05 | 2008-08-05 |
Publications (1)
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| KR20090061033A (ko) * | 2006-10-03 | 2009-06-15 | 와이어쓰 | 동결건조 방법 및 장치 |
| AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
| CN101801405A (zh) | 2007-08-07 | 2010-08-11 | 先进科技及再生医学有限责任公司 | 包含于酸性水溶液中的gdf-5的蛋白质配方 |
| JP5599778B2 (ja) * | 2008-04-14 | 2014-10-01 | デピュイ・シンセス・プロダクツ・エルエルシー | 液体緩衝ｇｄｆ−５製剤 |
| JP5785077B2 (ja) | 2008-08-05 | 2015-09-24 | ワイス・エルエルシー | 崩壊温度より高温での凍結乾燥 |
| SG11201505926VA (en) | 2013-03-15 | 2015-09-29 | Biogen Ma Inc | Factor ix polypeptide formulations |
| US11576863B2 (en) | 2013-03-15 | 2023-02-14 | Takeda Pharmaceutical Company Limited | Formulation of an antibody and use thereof |
| EA202092926A3 (ru) | 2014-03-24 | 2021-10-29 | Биовератив Терапьютикс Инк. | Лиофилизированные составы, содержащие фактор ix |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| EP3323410A1 (en) * | 2016-11-22 | 2018-05-23 | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. | Pharmaceutical parenteral formulation containing carglumic acid |
| CN107543373B (zh) * | 2017-09-06 | 2019-04-26 | 华派生物工程集团有限公司 | 一种活疫苗的冷冻干燥方法 |
| RS67656B1 (sr) | 2018-05-10 | 2026-02-27 | Regeneron Pharma | Formulacije koje sadrže visoke koncentracije fuzionog proteina vegf receptora |
| CN109369821B (zh) * | 2018-11-28 | 2021-12-14 | 四川恒通动保生物科技有限公司 | 一种黄芪多糖的高效提取制备方法 |
| PE20212185A1 (es) | 2019-02-18 | 2021-11-11 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos |
| WO2021158759A2 (en) | 2020-02-04 | 2021-08-12 | Regeneron Pharmaceuticals, Inc. | Target residual moisture content for lyophilized drug product |
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| US5298261A (en) * | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
| CA2191562A1 (en) * | 1994-06-03 | 1995-12-14 | Michelle Elizabeth Brideau | Fast dissolving dosage forms |
| RU2111426C1 (ru) | 1995-11-03 | 1998-05-20 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Способ лиофильной сушки биопрепарата |
| AU757002B2 (en) | 1998-03-03 | 2003-01-30 | Eli Lilly And Company | Pharmaceutical compositions containing the phospholipase inhibitor sodium ((3-(2-amino-1,2-dioxoethyl)-2-ethyl-1- phenylmethyl)-1H-indol-4-YL)oxy)acetate |
| EP1820516B1 (en) * | 1999-02-22 | 2013-07-24 | University of Connecticut | Novel albumin-free factor VIII formulations |
| GB9908014D0 (en) * | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
| GB0404586D0 (en) * | 2004-03-01 | 2004-04-07 | Britannia Pharmaceuticals Ltd | Improvements in or relating to organic materials |
| AU2005249530B2 (en) * | 2004-06-02 | 2012-04-12 | Victor Bronshtein | Preservation by vaporization |
| EP1796647B1 (en) * | 2004-08-12 | 2010-08-11 | Schering Corporation | Stable pegylated interferon formulation |
| WO2006029467A1 (en) | 2004-09-16 | 2006-03-23 | Btf Pty Ltd | Rapid freeze drying process |
| WO2006081320A2 (en) * | 2005-01-27 | 2006-08-03 | Human Genome Sciences, Inc. | Pharmaceutical formulation |
| JP5405122B2 (ja) * | 2005-12-21 | 2014-02-05 | ワイス・エルエルシー | 低粘度のタンパク質製剤およびその用途 |
| WO2009158529A2 (en) | 2008-06-26 | 2009-12-30 | Straher, Michael, P. | Lyophilization cycle robustness strategy |
| JP5785077B2 (ja) | 2008-08-05 | 2015-09-24 | ワイス・エルエルシー | 崩壊温度より高温での凍結乾燥 |
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| EP3572073A1 (en) | 2019-11-27 |
| EP3572073B1 (en) | 2023-12-20 |
| JP5785077B2 (ja) | 2015-09-24 |
| CA2729972A1 (en) | 2010-02-11 |
| JP2011530524A (ja) | 2011-12-22 |
| US20100041870A1 (en) | 2010-02-18 |
| WO2010017296A1 (en) | 2010-02-11 |
| CA2729972C (en) | 2018-11-20 |
| EP3572073C0 (en) | 2023-12-20 |
| ES2755029T3 (es) | 2020-04-21 |
| US9884019B2 (en) | 2018-02-06 |
| EP2323629B1 (en) | 2019-10-09 |
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