ES2961233T3 - Dispositivo de administración de agente terapéutico con cánula y aguja que pueden avanzar - Google Patents
Dispositivo de administración de agente terapéutico con cánula y aguja que pueden avanzar Download PDFInfo
- Publication number
- ES2961233T3 ES2961233T3 ES15770715T ES15770715T ES2961233T3 ES 2961233 T3 ES2961233 T3 ES 2961233T3 ES 15770715 T ES15770715 T ES 15770715T ES 15770715 T ES15770715 T ES 15770715T ES 2961233 T3 ES2961233 T3 ES 2961233T3
- Authority
- ES
- Spain
- Prior art keywords
- cannula
- needle
- drive assembly
- advance
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/02—Surgical instruments, devices or methods for holding wounds open, e.g. retractors; Tractors
- A61B17/0231—Surgical instruments, devices or methods for holding wounds open, e.g. retractors; Tractors for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3478—Endoscopic needles, e.g. for infusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B2017/347—Locking means, e.g. for locking instrument in cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462049135P | 2014-09-11 | 2014-09-11 | |
| US14/840,676 US10219936B2 (en) | 2014-09-11 | 2015-08-31 | Therapeutic agent delivery device with advanceable cannula and needle |
| PCT/US2015/049432 WO2016040636A1 (en) | 2014-09-11 | 2015-09-10 | Therapeutic agent delivery device with advanceable cannula and needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2961233T3 true ES2961233T3 (es) | 2024-03-11 |
Family
ID=55453674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15770715T Active ES2961233T3 (es) | 2014-09-11 | 2015-09-10 | Dispositivo de administración de agente terapéutico con cánula y aguja que pueden avanzar |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10219936B2 (https=) |
| EP (2) | EP4248922A3 (https=) |
| JP (1) | JP6608433B2 (https=) |
| KR (1) | KR102268213B1 (https=) |
| CN (2) | CN106999294A (https=) |
| AU (1) | AU2015315045B2 (https=) |
| BR (1) | BR112017004727B1 (https=) |
| CA (1) | CA2960975C (https=) |
| ES (1) | ES2961233T3 (https=) |
| MA (1) | MA40630A (https=) |
| MX (1) | MX2017003261A (https=) |
| PH (1) | PH12017500460A1 (https=) |
| RU (1) | RU2703689C2 (https=) |
| SG (1) | SG11201701969WA (https=) |
| WO (1) | WO2016040636A1 (https=) |
| ZA (1) | ZA201702520B (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9408746B2 (en) | 2010-03-31 | 2016-08-09 | Ocuject, Llc | Device and method for intraocular drug delivery |
| US9320647B2 (en) | 2010-03-31 | 2016-04-26 | Ocuject, Llc | Device and method for intraocular drug delivery |
| US9504603B2 (en) * | 2012-04-02 | 2016-11-29 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
| US9421129B2 (en) | 2012-04-02 | 2016-08-23 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
| USD746443S1 (en) * | 2013-10-02 | 2015-12-29 | Medical Instrument Development Laboratories, Inc. | Cannula insertion tool |
| US9968372B2 (en) | 2013-10-02 | 2018-05-15 | Medical Instrument Development Laboratories, Inc. | Cannula insertion tool |
| US9585790B2 (en) | 2013-11-14 | 2017-03-07 | Aquesys, Inc. | Intraocular shunt inserter |
| WO2015126694A1 (en) | 2014-02-12 | 2015-08-27 | Ethicon Endo-Surgery, Inc. | Method and apparatus for suprachoroidal administration of therapeutic agent |
| US10258502B2 (en) | 2014-09-18 | 2019-04-16 | Orbit Biomedical Limited | Therapeutic agent delivery device |
| US10376414B2 (en) * | 2015-12-14 | 2019-08-13 | Novartis Ag | Uni-port hybrid gauge surgical apparatuses and methods |
| US10478553B2 (en) * | 2016-03-09 | 2019-11-19 | Orbit Biomedical Limited | Apparatus for subretinal administration of therapeutic agent via a curved needle |
| US10390814B2 (en) | 2016-04-20 | 2019-08-27 | Medos International Sarl | Meniscal repair devices, systems, and methods |
| US10806629B2 (en) | 2016-06-17 | 2020-10-20 | Gyroscope Therapeutics Limited | Injection device for subretinal delivery of therapeutic agent |
| US10646374B2 (en) | 2016-06-17 | 2020-05-12 | Orbit Biomedical Limited | Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent |
| US11000410B2 (en) | 2016-06-17 | 2021-05-11 | Gyroscope Therapeutics Limited | Guide apparatus for tangential entry into suprachoroidal space |
| BR112019011964A2 (pt) * | 2016-12-19 | 2019-11-05 | New World Medical Inc | dispositivos de tratamento ocular e métodos de uso relacionados |
| US11273072B2 (en) | 2017-01-13 | 2022-03-15 | Gyroscope Therapeutics Limited | Suprachoroidal injection device |
| US11076984B2 (en) | 2017-03-13 | 2021-08-03 | Gyroscope Therapeutics Limited | Method of performing subretinal drainage and agent delivery |
| EP4324502B1 (en) * | 2018-03-09 | 2026-04-22 | Aquesys, Inc. | Intraocular shunt inserter |
| WO2019234542A1 (en) * | 2018-06-06 | 2019-12-12 | Alcon Inc. | Trocar cannula with a guidance valve |
| KR20210053309A (ko) * | 2018-08-29 | 2021-05-11 | 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． | 안구 수술 기구 |
| EP3870122B1 (en) * | 2018-10-24 | 2024-10-09 | New World Medical, Inc. | Ophthalmic device |
| US10722397B2 (en) | 2018-10-24 | 2020-07-28 | New World Medical, Inc. | Ophthalmic device |
| US11759355B1 (en) | 2019-02-26 | 2023-09-19 | Gyroscope Therapeutics Limited | Method of delivering leading blebs and agent to subretinal space |
| IL292024B1 (en) | 2019-10-11 | 2026-01-01 | Gyroscope Therapeutics Ltd | Syringe Dosing Cartridge Assembly |
| CA3188860A1 (en) * | 2020-08-12 | 2022-02-17 | Bryan Grygus | Systems and methods for drug delivery to ocular tissue |
| EP4461330A4 (en) * | 2022-01-04 | 2025-04-16 | Eoflow Co., Ltd. | NEEDLE ASSEMBLY AND LIQUID MEDICATION INJECTION DEVICE THEREOF |
| USD1037439S1 (en) | 2022-01-17 | 2024-07-30 | EyePoint Pharamaceuticals, Inc. | Ocular injector |
| US12575968B2 (en) * | 2022-03-23 | 2026-03-17 | New World Medical, Inc. | Ophthalmic device |
| US20230310810A1 (en) * | 2022-03-31 | 2023-10-05 | Alcon Inc. | Slotted tubing security platform |
| WO2024052733A1 (en) | 2022-09-06 | 2024-03-14 | Gyroscope Therapeutics Limited | Apparatus for subretinal administration of therapeutic agent via dual-curved needle |
| EP4648726A2 (en) * | 2023-01-13 | 2025-11-19 | Genentech, Inc. | Dose dock for syringe |
| WO2025039064A1 (en) * | 2023-08-23 | 2025-02-27 | Precision Retina Inc. | Devices and methods for posterior eye segment access with accurate localization and needle penetration depth |
| WO2025072094A1 (en) * | 2023-09-25 | 2025-04-03 | Amgen Inc. | Drug delivery device having a rear cap for increased drop robustness |
| TW202529711A (zh) | 2023-09-29 | 2025-08-01 | 美商建南德克公司 | 眼插管導引器、施用器及標記器械 |
| TW202602405A (zh) | 2024-03-27 | 2026-01-16 | 美商建南德克公司 | 用於視網膜下注射裝置的扭矩環 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1285441C (en) * | 1987-03-17 | 1991-07-02 | Roy D. Mcnaughton | Mcnaughton syringe shield type b |
| DE19741487C2 (de) * | 1997-09-19 | 2000-08-31 | Univ Eberhard Karls | Vorrichtung für einen Zugang in den Subretinalraum eines Auges |
| US6368315B1 (en) | 1999-06-23 | 2002-04-09 | Durect Corporation | Composite drug delivery catheter |
| US6585694B1 (en) * | 2000-09-07 | 2003-07-01 | Syntheon, Llc | Knob-controlled endoscopic needle device |
| US7431710B2 (en) * | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| WO2003068053A2 (en) | 2002-02-14 | 2003-08-21 | Photogenesis, Inc. | Subretinal implantation device and surgical cannulas for use therewith |
| AU2003256657A1 (en) * | 2002-07-19 | 2004-02-09 | Yale University | Uveoscleral drainage device |
| WO2004028477A2 (en) | 2002-09-29 | 2004-04-08 | Surmodics, Inc. | Methods for treatment and/or prevention of retinal disease |
| US20040199130A1 (en) * | 2003-04-03 | 2004-10-07 | Chornenky Victor I. | Apparatus and method for treatment of macular degeneration |
| EP2399990B1 (en) | 2003-06-27 | 2015-07-22 | DePuy Synthes Products, Inc. | Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system |
| US6939325B2 (en) * | 2003-11-28 | 2005-09-06 | Michael L. Haining | Intravenous catheter and insertion device |
| DK1715827T3 (da) | 2004-01-23 | 2011-04-18 | Iscience Interventional Corp | Sammensat ophthalmisk mikrokanyle |
| CN101052434A (zh) * | 2004-04-29 | 2007-10-10 | I科学干预公司 | 用于治疗眼睛的装置和方法 |
| ZA200609408B (en) * | 2004-04-29 | 2008-02-27 | Iscience Interventional Corp | Apparatus and method for surgical enhancement of aqueous humor drainage |
| US20080058704A1 (en) | 2004-04-29 | 2008-03-06 | Michael Hee | Apparatus and Method for Ocular Treatment |
| US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
| EP3838236B1 (en) * | 2006-01-17 | 2025-08-13 | Alcon Inc. | Glaucoma treatment device |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US20120197175A1 (en) | 2006-06-30 | 2012-08-02 | Aquesys, Inc. | Methods, systems and apparatus for relieving pressure in an organ |
| EP2063777A2 (en) * | 2006-09-19 | 2009-06-03 | The Trustees of Columbia University in the City of New York | Systems, devices, and methods for surgery on a hollow anatomically suspended organ |
| US20080281292A1 (en) * | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
| US9399130B2 (en) | 2007-04-25 | 2016-07-26 | Medtronic, Inc. | Cannula configured to deliver test stimulation |
| WO2009012406A1 (en) * | 2007-07-17 | 2009-01-22 | Transcend Medical, Inc. | Ocular implant with hydrogel expansion capabilities reference to priority document |
| DK2227257T3 (da) * | 2008-01-07 | 2013-09-30 | Salutaris Medical Devices Inc | Anordninger til minimal-invasiv ekstraokular afgivelse af stråling til den posteriore del af øjet |
| JP2011513002A (ja) * | 2008-03-05 | 2011-04-28 | イバンティス インコーポレイテッド | 緑内障を治療する方法及び器具 |
| US8425473B2 (en) | 2009-01-23 | 2013-04-23 | Iscience Interventional Corporation | Subretinal access device |
| US8287494B2 (en) | 2009-03-23 | 2012-10-16 | Colin Ma | Intravitreal injection devices and methods of injecting a substance into the vitreous chamber of the eye |
| CN102458509B (zh) * | 2009-05-15 | 2015-04-22 | I科学干预公司 | 用于视网膜下导管插入的装置 |
| JP2013508096A (ja) * | 2009-10-23 | 2013-03-07 | イバンティス インコーポレイテッド | 眼内移植システムおよび眼内移植方法 |
| US9408746B2 (en) | 2010-03-31 | 2016-08-09 | Ocuject, Llc | Device and method for intraocular drug delivery |
| US8523873B2 (en) * | 2010-04-08 | 2013-09-03 | Warsaw Orthopedic, Inc. | Neural-monitoring enabled sleeves for surgical instruments |
| US20120271272A1 (en) | 2010-10-15 | 2012-10-25 | Iscience Interventional Corporation | Device for ocular access |
| US8663150B2 (en) * | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
| US9216109B2 (en) * | 2012-03-20 | 2015-12-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US9241832B2 (en) * | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
| EP2887982B1 (en) | 2012-08-27 | 2022-11-23 | Clearside Biomedical, Inc. | Apparatus for drug delivery using microneedles |
| EP2916827B1 (en) | 2012-11-08 | 2020-06-10 | Clearside Biomedical Inc. | Methods for the treatment of ocular disease in human subjects |
| WO2015126694A1 (en) | 2014-02-12 | 2015-08-27 | Ethicon Endo-Surgery, Inc. | Method and apparatus for suprachoroidal administration of therapeutic agent |
| KR102511477B1 (ko) | 2014-06-17 | 2023-03-16 | 클리어사이드 바이오메디컬, 인코포레이드 | 안구 후부 질환을 치료하기 위한 방법 및 디바이스 |
| RU2710491C2 (ru) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань |
| CA2956273A1 (en) * | 2014-08-12 | 2016-02-18 | Patrick Gooi | Device, delivery system, and method for ocular therapy |
| GB201516066D0 (en) | 2015-09-10 | 2015-10-28 | Young & Co Llp D | Treatment of retinitis pigmentosa |
-
2015
- 2015-08-31 US US14/840,676 patent/US10219936B2/en active Active
- 2015-09-10 CN CN201580049287.XA patent/CN106999294A/zh active Pending
- 2015-09-10 MX MX2017003261A patent/MX2017003261A/es unknown
- 2015-09-10 CN CN201911250714.7A patent/CN110960348A/zh active Pending
- 2015-09-10 EP EP23191369.0A patent/EP4248922A3/en not_active Withdrawn
- 2015-09-10 AU AU2015315045A patent/AU2015315045B2/en active Active
- 2015-09-10 CA CA2960975A patent/CA2960975C/en active Active
- 2015-09-10 SG SG11201701969WA patent/SG11201701969WA/en unknown
- 2015-09-10 MA MA040630A patent/MA40630A/fr unknown
- 2015-09-10 KR KR1020177009664A patent/KR102268213B1/ko active Active
- 2015-09-10 RU RU2017112035A patent/RU2703689C2/ru active
- 2015-09-10 JP JP2017513693A patent/JP6608433B2/ja active Active
- 2015-09-10 BR BR112017004727-6A patent/BR112017004727B1/pt active IP Right Grant
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- 2015-09-10 WO PCT/US2015/049432 patent/WO2016040636A1/en not_active Ceased
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2017
- 2017-03-10 PH PH12017500460A patent/PH12017500460A1/en unknown
- 2017-04-10 ZA ZA2017/02520A patent/ZA201702520B/en unknown
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| Publication number | Publication date |
|---|---|
| EP3191031A1 (en) | 2017-07-19 |
| ZA201702520B (en) | 2019-06-26 |
| AU2015315045B2 (en) | 2019-04-04 |
| KR20170052663A (ko) | 2017-05-12 |
| EP4248922A3 (en) | 2024-01-10 |
| RU2017112035A (ru) | 2018-10-11 |
| CN106999294A (zh) | 2017-08-01 |
| CN110960348A (zh) | 2020-04-07 |
| JP2017526477A (ja) | 2017-09-14 |
| JP6608433B2 (ja) | 2019-11-20 |
| AU2015315045A1 (en) | 2017-03-30 |
| RU2017112035A3 (https=) | 2019-04-12 |
| RU2703689C2 (ru) | 2019-10-21 |
| EP4248922A2 (en) | 2023-09-27 |
| MX2017003261A (es) | 2018-02-23 |
| EP3191031B1 (en) | 2023-08-16 |
| SG11201701969WA (en) | 2017-04-27 |
| KR102268213B1 (ko) | 2021-06-24 |
| CA2960975A1 (en) | 2016-03-17 |
| WO2016040636A1 (en) | 2016-03-17 |
| PH12017500460A1 (en) | 2017-07-31 |
| MA40630A (fr) | 2016-03-17 |
| US20160074211A1 (en) | 2016-03-17 |
| CA2960975C (en) | 2021-05-18 |
| US10219936B2 (en) | 2019-03-05 |
| BR112017004727B1 (pt) | 2021-12-21 |
| BR112017004727A2 (pt) | 2017-12-05 |
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