ES2947591T3 - Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales - Google Patents

Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales Download PDF

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Publication number
ES2947591T3
ES2947591T3 ES16721609T ES16721609T ES2947591T3 ES 2947591 T3 ES2947591 T3 ES 2947591T3 ES 16721609 T ES16721609 T ES 16721609T ES 16721609 T ES16721609 T ES 16721609T ES 2947591 T3 ES2947591 T3 ES 2947591T3
Authority
ES
Spain
Prior art keywords
cys
seq
tyr
glu leu
pro ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16721609T
Other languages
English (en)
Spanish (es)
Inventor
Mark Currie
Robert Solinga
Christopher Leitheiser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ironwood Pharmaceuticals Inc
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2947591T3 publication Critical patent/ES2947591T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES16721609T 2015-05-01 2016-04-29 Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales Active ES2947591T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562156077P 2015-05-01 2015-05-01
PCT/US2016/030061 WO2016178979A1 (en) 2015-05-01 2016-04-29 Compositions for colon cleansing and the treatment of gastrointestinal disorders

Publications (1)

Publication Number Publication Date
ES2947591T3 true ES2947591T3 (es) 2023-08-11

Family

ID=55953439

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16721609T Active ES2947591T3 (es) 2015-05-01 2016-04-29 Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales

Country Status (23)

Country Link
US (2) US10618938B2 (https=)
EP (2) EP3288578B8 (https=)
JP (5) JP6930919B2 (https=)
KR (2) KR20250042844A (https=)
CN (2) CN108040482B (https=)
CA (2) CA3172777A1 (https=)
CY (1) CY1126031T1 (https=)
DK (1) DK3288578T5 (https=)
EA (1) EA201792401A1 (https=)
ES (1) ES2947591T3 (https=)
FI (1) FI3288578T3 (https=)
HR (1) HRP20230381T1 (https=)
HU (1) HUE061954T2 (https=)
LT (1) LT3288578T (https=)
MA (1) MA41985B1 (https=)
MD (1) MD3288578T2 (https=)
MX (2) MX2017013928A (https=)
PL (1) PL3288578T3 (https=)
PT (1) PT3288578T (https=)
RS (1) RS64160B1 (https=)
SI (1) SI3288578T1 (https=)
SM (1) SMT202300114T1 (https=)
WO (1) WO2016178979A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2947591T3 (es) * 2015-05-01 2023-08-11 Ironwood Pharmaceuticals Inc Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales
EP4067368A1 (en) 2016-06-01 2022-10-05 Athira Pharma, Inc. Compounds
IL312992A (en) * 2021-11-24 2024-07-01 Ironwood Pharmaceuticals Inc A synthetic process for the production of modified GCC receptor agonists
CN118696053A (zh) * 2021-11-24 2024-09-24 硬木药品公司 用于产生修饰的gcc受体激动剂的合成方法
IL313184A (en) * 2021-11-29 2024-07-01 Ironwood Pharmaceuticals Inc Pharmaceutical compositions for the treatment of visceral pain
WO2026050206A1 (en) * 2024-08-27 2026-03-05 Ironwood Pharmaceuticals, Inc. Combinations of glp-1 and guanylate cyclase c (gc-c) receptor agonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH689139A5 (de) 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
SG168407A1 (en) * 2003-01-28 2011-02-28 Ironwood Pharmaceuticals Inc Methods and compositions for the treatment of gastrointestinal disorders
US7494979B2 (en) * 2003-06-13 2009-02-24 Ironwood Pharmaceuticals, Inc. Method for treating congestive heart failure and other disorders
EP1940441A4 (en) * 2005-08-19 2010-01-27 Ironwood Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL DISORDERS
WO2010025510A1 (en) * 2008-09-03 2010-03-11 Xenome Ltd Libraries of peptide conjugates and methods for making them
US8933030B2 (en) * 2010-02-17 2015-01-13 Ironwwod Pharmaceuticals, Inc. Treatments for gastrointestinal disorders
ES2664873T3 (es) * 2011-03-01 2018-04-23 Synergy Pharmaceuticals Inc. Proceso de preparación de agonistas de guanilato ciclasa C
US9545446B2 (en) * 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
SI3004138T1 (sl) * 2013-06-05 2024-07-31 Bausch Health Ireland Limited Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo
WO2016015055A1 (en) * 2014-07-25 2016-01-28 Ironwood Pharmaceuticals, Inc. Colon cleansing compositions
ES2947591T3 (es) * 2015-05-01 2023-08-11 Ironwood Pharmaceuticals Inc Composiciones para la limpieza del colon y el tratamiento de trastornos gastrointestinales

Also Published As

Publication number Publication date
DK3288578T3 (da) 2023-05-01
MA41985A (fr) 2018-03-07
MX2017013928A (es) 2018-01-15
MA41985B1 (fr) 2023-04-28
US10618938B2 (en) 2020-04-14
EP4218789A3 (en) 2023-09-27
EA201792401A1 (ru) 2018-05-31
US20180148476A1 (en) 2018-05-31
CN108040482A (zh) 2018-05-15
US20240199697A1 (en) 2024-06-20
MX2022013283A (es) 2022-12-13
CA2984437C (en) 2025-11-18
EP3288578B1 (en) 2023-03-15
KR102783759B1 (ko) 2025-03-21
EP3288578A1 (en) 2018-03-07
PL3288578T3 (pl) 2023-08-14
CA2984437A1 (en) 2016-11-10
HRP20230381T1 (hr) 2023-07-07
JP2018519254A (ja) 2018-07-19
JP6930919B2 (ja) 2021-09-01
JP2022121734A (ja) 2022-08-19
CA3172777A1 (en) 2016-11-10
HUE061954T2 (hu) 2023-09-28
PT3288578T (pt) 2023-03-28
LT3288578T (lt) 2023-04-25
EP3288578B8 (en) 2023-03-29
RS64160B1 (sr) 2023-05-31
KR20250042844A (ko) 2025-03-27
BR112017023539A2 (pt) 2018-08-14
SMT202300114T1 (it) 2023-05-12
JP2024015335A (ja) 2024-02-01
CY1126031T1 (el) 2023-11-15
MD3288578T2 (ro) 2023-08-31
FI3288578T3 (fi) 2023-05-03
CN108040482B (zh) 2022-03-29
CN114716514A (zh) 2022-07-08
KR20180005675A (ko) 2018-01-16
JP2025169325A (ja) 2025-11-12
SI3288578T1 (sl) 2023-07-31
JP2020203954A (ja) 2020-12-24
DK3288578T5 (da) 2024-10-07
EP4218789A2 (en) 2023-08-02
WO2016178979A1 (en) 2016-11-10

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