KR102783759B1 - 결장 세정을 위한 조성물 및 위장 장애의 치료 - Google Patents

결장 세정을 위한 조성물 및 위장 장애의 치료 Download PDF

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Publication number
KR102783759B1
KR102783759B1 KR1020177034808A KR20177034808A KR102783759B1 KR 102783759 B1 KR102783759 B1 KR 102783759B1 KR 1020177034808 A KR1020177034808 A KR 1020177034808A KR 20177034808 A KR20177034808 A KR 20177034808A KR 102783759 B1 KR102783759 B1 KR 102783759B1
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seq
glu leu
tyr
cth
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Korean (ko)
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KR20180005675A (ko
Inventor
마크 지. 커리
로버트 솔링가
크리스토퍼 라이티저
Original Assignee
아이언우드 파마슈티컬스, 인코포레이티드
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Priority to KR1020257008457A priority Critical patent/KR20250042844A/ko
Publication of KR20180005675A publication Critical patent/KR20180005675A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020177034808A 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료 Active KR102783759B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257008457A KR20250042844A (ko) 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562156077P 2015-05-01 2015-05-01
US62/156,077 2015-05-01
PCT/US2016/030061 WO2016178979A1 (en) 2015-05-01 2016-04-29 Compositions for colon cleansing and the treatment of gastrointestinal disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257008457A Division KR20250042844A (ko) 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료

Publications (2)

Publication Number Publication Date
KR20180005675A KR20180005675A (ko) 2018-01-16
KR102783759B1 true KR102783759B1 (ko) 2025-03-21

Family

ID=55953439

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020177034808A Active KR102783759B1 (ko) 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료
KR1020257008457A Pending KR20250042844A (ko) 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020257008457A Pending KR20250042844A (ko) 2015-05-01 2016-04-29 결장 세정을 위한 조성물 및 위장 장애의 치료

Country Status (23)

Country Link
US (2) US10618938B2 (https=)
EP (2) EP4218789A3 (https=)
JP (5) JP6930919B2 (https=)
KR (2) KR102783759B1 (https=)
CN (2) CN108040482B (https=)
CA (2) CA3172777A1 (https=)
CY (1) CY1126031T1 (https=)
DK (1) DK3288578T5 (https=)
EA (1) EA201792401A1 (https=)
ES (1) ES2947591T3 (https=)
FI (1) FI3288578T3 (https=)
HR (1) HRP20230381T1 (https=)
HU (1) HUE061954T2 (https=)
LT (1) LT3288578T (https=)
MA (1) MA41985B1 (https=)
MD (1) MD3288578T2 (https=)
MX (2) MX2017013928A (https=)
PL (1) PL3288578T3 (https=)
PT (1) PT3288578T (https=)
RS (1) RS64160B1 (https=)
SI (1) SI3288578T1 (https=)
SM (1) SMT202300114T1 (https=)
WO (1) WO2016178979A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3288578T2 (ro) * 2015-05-01 2023-08-31 Ironwood Pharmaceuticals Inc Compoziții pentru curățarea colonului și tratamentul tulburărilor gastrointestinale
US11021514B2 (en) 2016-06-01 2021-06-01 Athira Pharma, Inc. Compounds
MX2024006317A (es) * 2021-11-24 2024-06-19 Ironwood Pharmaceuticals Inc Proceso sintetico para la produccion de agonistas del receptor de guanilato ciclasa c (gcc) modificados.
JP2024541769A (ja) * 2021-11-24 2024-11-12 アイアンウッド ファーマシューティカルズ， インコーポレイテッド 修飾ｇｃｃ受容体アゴニストの産生のための合成プロセス
IL313184A (en) 2021-11-29 2024-07-01 Ironwood Pharmaceuticals Inc Pharmaceutical compositions for the treatment of visceral pain
WO2026050206A1 (en) * 2024-08-27 2026-03-05 Ironwood Pharmaceuticals, Inc. Combinations of glp-1 and guanylate cyclase c (gc-c) receptor agonists

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014131024A2 (en) * 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
CH689139A5 (de) 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
EP1911763B1 (en) * 2003-01-28 2010-08-11 Ironwood Pharmaceuticals, Inc. Compositions for the treatment of gastrointestinal disorders
US7494979B2 (en) * 2003-06-13 2009-02-24 Ironwood Pharmaceuticals, Inc. Method for treating congestive heart failure and other disorders
WO2007022531A2 (en) * 2005-08-19 2007-02-22 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20110172126A1 (en) * 2008-09-03 2011-07-14 Xenome Ltd Libraries of peptide conjugates and methods for making them
UA108636C2 (xx) * 2010-02-17 2015-05-25 Пептид
DK2681236T3 (en) * 2011-03-01 2018-04-16 Synergy Pharmaceuticals Inc PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
WO2016015055A1 (en) 2014-07-25 2016-01-28 Ironwood Pharmaceuticals, Inc. Colon cleansing compositions
MD3288578T2 (ro) * 2015-05-01 2023-08-31 Ironwood Pharmaceuticals Inc Compoziții pentru curățarea colonului și tratamentul tulburărilor gastrointestinale

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014131024A2 (en) * 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Akhter Hossain M. et al, Org. Biomol. Chem., 7:pp.1547~1553 (2009)*

Also Published As

Publication number Publication date
MA41985A (fr) 2018-03-07
MX2017013928A (es) 2018-01-15
EA201792401A1 (ru) 2018-05-31
PL3288578T3 (pl) 2023-08-14
ES2947591T3 (es) 2023-08-11
LT3288578T (lt) 2023-04-25
CA2984437A1 (en) 2016-11-10
JP2020203954A (ja) 2020-12-24
MD3288578T2 (ro) 2023-08-31
US10618938B2 (en) 2020-04-14
BR112017023539A2 (pt) 2018-08-14
SI3288578T1 (sl) 2023-07-31
JP2025169325A (ja) 2025-11-12
WO2016178979A1 (en) 2016-11-10
JP2018519254A (ja) 2018-07-19
JP2022121734A (ja) 2022-08-19
CN108040482A (zh) 2018-05-15
EP3288578A1 (en) 2018-03-07
MX2022013283A (es) 2022-12-13
EP3288578B1 (en) 2023-03-15
CN108040482B (zh) 2022-03-29
CA2984437C (en) 2025-11-18
JP2024015335A (ja) 2024-02-01
KR20250042844A (ko) 2025-03-27
MA41985B1 (fr) 2023-04-28
EP4218789A3 (en) 2023-09-27
US20180148476A1 (en) 2018-05-31
DK3288578T5 (da) 2024-10-07
HUE061954T2 (hu) 2023-09-28
DK3288578T3 (da) 2023-05-01
FI3288578T3 (fi) 2023-05-03
RS64160B1 (sr) 2023-05-31
CA3172777A1 (en) 2016-11-10
HRP20230381T1 (hr) 2023-07-07
CY1126031T1 (el) 2023-11-15
KR20180005675A (ko) 2018-01-16
US20240199697A1 (en) 2024-06-20
EP3288578B8 (en) 2023-03-29
SMT202300114T1 (it) 2023-05-12
EP4218789A2 (en) 2023-08-02
CN114716514A (zh) 2022-07-08
JP6930919B2 (ja) 2021-09-01
PT3288578T (pt) 2023-03-28

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