ES2945822T3 - Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación - Google Patents

Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación Download PDF

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Publication number
ES2945822T3
ES2945822T3 ES21170218T ES21170218T ES2945822T3 ES 2945822 T3 ES2945822 T3 ES 2945822T3 ES 21170218 T ES21170218 T ES 21170218T ES 21170218 T ES21170218 T ES 21170218T ES 2945822 T3 ES2945822 T3 ES 2945822T3
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ES
Spain
Prior art keywords
compound
sana
available
subject
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES21170218T
Other languages
English (en)
Spanish (es)
Inventor
Carlos Batthyany
Gloria Lopez
Carlos Escande
Duarte Jorge Rodriguez
Quinta Williams Porcal
Capuccio Rosina Dapueto
Lopez Germán Galliussi
Nunez María Garat
Marcelo Hill
Mercedes Segovia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de la Republica
Institut Pasteur de Montevideo
Original Assignee
Universidad de la Republica
Institut Pasteur de Montevideo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de la Republica, Institut Pasteur de Montevideo filed Critical Universidad de la Republica
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Publication of ES2945822T3 publication Critical patent/ES2945822T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES21170218T 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación Active ES2945822T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662408459P 2016-10-14 2016-10-14
US201762570973P 2017-10-11 2017-10-11

Publications (1)

Publication Number Publication Date
ES2945822T3 true ES2945822T3 (es) 2023-07-07

Family

ID=60382484

Family Applications (2)

Application Number Title Priority Date Filing Date
ES21170218T Active ES2945822T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación
ES17800605T Active ES2886122T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES17800605T Active ES2886122T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación

Country Status (9)

Country Link
US (3) US10537537B2 (cg-RX-API-DMAC7.html)
EP (2) EP3878456B1 (cg-RX-API-DMAC7.html)
JP (1) JP6923659B2 (cg-RX-API-DMAC7.html)
CN (1) CN110325182B (cg-RX-API-DMAC7.html)
AU (1) AU2017342167B2 (cg-RX-API-DMAC7.html)
CL (1) CL2019001014A1 (cg-RX-API-DMAC7.html)
ES (2) ES2945822T3 (cg-RX-API-DMAC7.html)
MX (1) MX394475B (cg-RX-API-DMAC7.html)
WO (1) WO2018069907A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2945822T3 (es) * 2016-10-14 2023-07-07 Inst Pasteur De Montevideo Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación
JOP20190080A1 (ar) 2016-10-14 2019-04-11 Bayer Pharma AG مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
US11400066B2 (en) * 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
NZ765463A (en) * 2017-12-27 2025-11-28 Batthyany Carlos Nitroalkene non steroidal anti-inflammatory drugs (na-nsaids) and methods of treating inflammation related conditions
US10632132B2 (en) * 2018-01-24 2020-04-28 Carlos Batthyány Methods for treating heart transplant rejection
WO2020058917A1 (en) * 2018-09-20 2020-03-26 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113140B2 (cg-RX-API-DMAC7.html) * 1972-01-13 1976-04-26
JPS5113140A (en) 1974-07-23 1976-02-02 Sankyo Alu Ind Kinzokuseitoshojino nakazan
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
WO2005037323A2 (en) * 2003-10-10 2005-04-28 University Of Louisville Research Foundation, Inc. Use of gro to treat or prevent inflammation
US20060247263A1 (en) * 2005-04-19 2006-11-02 Amgen Inc. Substituted heterocyclic compounds and methods of use
JP2012513774A (ja) * 2008-12-31 2012-06-21 ニトロメガ コーポレーション ニトロ脂肪酸を含有する栄養補助物
EP2847152A4 (en) 2012-05-10 2016-03-23 Cellix Bio Private Ltd COMPOSITIONS AND METHOD FOR THE TREATMENT OF METABOLIC SYNDROME
WO2015073527A1 (en) 2013-11-12 2015-05-21 Complexa, Inc. Nitroalkene tocopherols and analogs thereof for use in the treatment and prevention of inflammation related conditions
ES2945822T3 (es) 2016-10-14 2023-07-07 Inst Pasteur De Montevideo Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
US10632132B2 (en) * 2018-01-24 2020-04-28 Carlos Batthyány Methods for treating heart transplant rejection
WO2020058917A1 (en) 2018-09-20 2020-03-26 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Also Published As

Publication number Publication date
US20250352501A1 (en) 2025-11-20
AU2017342167A1 (en) 2019-06-06
CN110325182B (zh) 2023-05-23
JP6923659B2 (ja) 2021-08-25
JP2019531356A (ja) 2019-10-31
US10537537B2 (en) 2020-01-21
ES2886122T3 (es) 2021-12-16
MX394475B (es) 2025-03-24
CL2019001014A1 (es) 2019-11-29
US20220296546A1 (en) 2022-09-22
EP3525780A1 (en) 2019-08-21
AU2017342167B2 (en) 2023-01-12
EP3878456A1 (en) 2021-09-15
WO2018069907A1 (en) 2018-04-19
CN110325182A (zh) 2019-10-11
US20180104202A1 (en) 2018-04-19
EP3525780B1 (en) 2021-06-02
EP3878456B1 (en) 2023-03-15
US12280029B2 (en) 2025-04-22
MX2019004402A (es) 2019-09-26

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