ES292867A1 - Procedimiento para la preparaciën de i-fenil-2-aminopropanos n-sustituidos - Google Patents
Procedimiento para la preparaciën de i-fenil-2-aminopropanos n-sustituidosInfo
- Publication number
- ES292867A1 ES292867A1 ES0292867A ES292867A ES292867A1 ES 292867 A1 ES292867 A1 ES 292867A1 ES 0292867 A ES0292867 A ES 0292867A ES 292867 A ES292867 A ES 292867A ES 292867 A1 ES292867 A1 ES 292867A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- ethyl
- group
- compounds
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 9
- 239000002253 acid Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 150000001299 aldehydes Chemical class 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- KWTSXDURSIMDCE-UHFFFAOYSA-N 1-phenylpropan-2-amine Chemical compound CC(N)CC1=CC=CC=C1 KWTSXDURSIMDCE-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- -1 amino compound Chemical class 0.000 abstract 2
- 238000009833 condensation Methods 0.000 abstract 2
- 230000005494 condensation Effects 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- QCCDLTOVEPVEJK-UHFFFAOYSA-N phenylacetone Chemical compound CC(=O)CC1=CC=CC=C1 QCCDLTOVEPVEJK-UHFFFAOYSA-N 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39753/62A GB1006588A (en) | 1962-10-19 | 1962-10-19 | N-substituted-1-phenyl-2-aminopropanes |
Publications (1)
Publication Number | Publication Date |
---|---|
ES292867A1 true ES292867A1 (es) | 1964-04-01 |
Family
ID=10411293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0292867A Expired ES292867A1 (es) | 1962-10-19 | 1963-10-18 | Procedimiento para la preparaciën de i-fenil-2-aminopropanos n-sustituidos |
Country Status (12)
Country | Link |
---|---|
US (1) | US3359263A (en, 2012) |
BE (1) | BE638839A (en, 2012) |
BR (1) | BR6353836D0 (en, 2012) |
CH (1) | CH455754A (en, 2012) |
DE (1) | DE1214688B (en, 2012) |
DK (2) | DK109925C (en, 2012) |
ES (1) | ES292867A1 (en, 2012) |
FI (2) | FI42543B (en, 2012) |
FR (2) | FR1450391A (en, 2012) |
GB (1) | GB1006588A (en, 2012) |
NL (2) | NL133997C (en, 2012) |
SE (1) | SE313301B (en, 2012) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR145F (en, 2012) * | 1964-06-01 | |||
US3452009A (en) * | 1965-05-03 | 1969-06-24 | Merck & Co Inc | 2,3-epoxypropylidene derivative of 5h-dibenzo(a,d)-10,11-dihydrocycloheptenes |
US4267192A (en) * | 1980-03-11 | 1981-05-12 | American Home Products Corporation | Method for treating inflammation |
FR2499556B1 (en, 2012) * | 1981-02-10 | 1983-03-25 | Cird | |
WO1997046549A1 (en) * | 1996-06-05 | 1997-12-11 | Novartis Ag | Anti-neurodegeneratively effective xanthene derivatives |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2676971A (en) * | 1951-04-21 | 1954-04-27 | Searle & Co | Quaternary ammonium derivatives of aminoalkylxanthenes and aminoalkylthiaxanthenes |
US3073847A (en) * | 1959-02-12 | 1963-01-15 | Hoffmann La Roche | 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation |
NL274885A (en, 2012) * | 1960-09-16 | |||
BE630063A (en, 2012) * | 1962-03-23 | |||
US3258459A (en) * | 1962-08-30 | 1966-06-28 | Squibb & Sons Inc | Method for the preparation of n-monosubstituted-secondary aminoalkyl derivatives of polycyclic compounds |
US3264342A (en) * | 1963-05-24 | 1966-08-02 | Geigy Chem Corp | Derivatives of 5h-dibenzo[a, d] cycloheptene |
US3258488A (en) * | 1963-08-12 | 1966-06-28 | Colgate Palmolive Co | Dibenzo[a, d]cycloheptene derivatives |
-
0
- NL NL299449D patent/NL299449A/xx unknown
- NL NL133997D patent/NL133997C/xx active
- BE BE638839D patent/BE638839A/xx unknown
-
1962
- 1962-10-19 GB GB39753/62A patent/GB1006588A/en not_active Expired
-
1963
- 1963-08-16 US US302707A patent/US3359263A/en not_active Expired - Lifetime
- 1963-10-17 FI FI2027/63A patent/FI42543B/fi active
- 1963-10-18 ES ES0292867A patent/ES292867A1/es not_active Expired
- 1963-10-18 BR BR153836/63A patent/BR6353836D0/pt unknown
- 1963-10-18 DK DK493363AA patent/DK109925C/da active
- 1963-10-18 DE DEN23907A patent/DE1214688B/de active Pending
- 1963-10-18 CH CH1280863A patent/CH455754A/de unknown
- 1963-10-18 FR FR951049A patent/FR1450391A/fr not_active Expired
- 1963-10-19 SE SE11503/63A patent/SE313301B/xx unknown
-
1964
- 1964-01-17 FR FR960756A patent/FR3974M/fr not_active Expired
-
1966
- 1966-02-21 DK DK90066AA patent/DK111174B/da unknown
-
1969
- 1969-07-28 FI FI2232/69A patent/FI44241B/fi active
Also Published As
Publication number | Publication date |
---|---|
SE313301B (en, 2012) | 1969-08-11 |
DE1214688B (de) | 1966-04-21 |
NL299449A (en, 2012) | |
US3359263A (en) | 1967-12-19 |
BE638839A (en, 2012) | |
FR3974M (en, 2012) | 1966-03-07 |
GB1006588A (en) | 1965-10-06 |
FI42543B (en, 2012) | 1970-06-01 |
NL133997C (en, 2012) | |
CH455754A (de) | 1968-05-15 |
BR6353836D0 (pt) | 1973-07-12 |
DK109925C (da) | 1968-08-05 |
FR1450391A (fr) | 1966-06-24 |
FI44241B (en, 2012) | 1971-06-30 |
DK111174B (da) | 1968-06-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3123646A (en) | Primary acyclic amines | |
US2705726A (en) | Iodinated aminophenyl-carboxylic acids | |
DE2047028B2 (de) | p-Alkylthiophenyl-äthanolamine und deren Salze, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung | |
US3859338A (en) | Derivatives of 4-(4'-biphenylyl)-3-or-2-butenoic acid and salts thereof | |
DE1795841C3 (de) | H2'-Chlor)-benzyl-2-di-sec.-butylamino-acetyl-pyrrol, seine Salze und Verfahren zu deren Herstellung | |
ES292867A1 (es) | Procedimiento para la preparaciën de i-fenil-2-aminopropanos n-sustituidos | |
US2668850A (en) | Phenyl-phenethyl ketones | |
GB1377209A (en) | Optically active basically substituted phenylacetonitriles | |
Rohrmann et al. | The use of chalcones in the synthesis of medicinal intermediates | |
DE2920812C2 (en, 2012) | ||
DE2938571A1 (de) | Epoxysuccinamidsaeureverbindungen und diese verbindungen enthaltende arzneimittel | |
DE1936206A1 (de) | Diphenylmethoxyaethylaminoderivate und Verfahren zu ihrer Herstellung | |
CH637108A5 (en) | Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes | |
US3507919A (en) | Triphenylpropyl amines | |
US3467710A (en) | Beta-(4- or 5-phenyl-1-naphthalene) ethylamines | |
Feuer et al. | The Chemistry of Cyclic Hydrazides. 1 VII. The Course of the Michael-Type Addition with Cyclic Hydrazides2 | |
Sax et al. | Retention of configuration in the Wolff rearrangement | |
GB1220750A (en) | New spiro-azatetramethylene derivatives | |
US2797233A (en) | Basic derivatives of substituted oxygenated phenylpropionic acids and methods of preparing same | |
US3095448A (en) | Cycloalkyl-alkyl hydrazines | |
DE2245467A1 (de) | Benzoesaeurederivate | |
Burckhalter et al. | Esters of α-(2-Dialkylaminoethyl)-benzyl Alcohols | |
US4201790A (en) | Benzophenone derivatives | |
DE3726633A1 (de) | Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten | |
Sunko et al. | Studies in the Sphingolipids Series. II. Synthesis of Enantiomeric Sphingines |