ES2924235T3 - Andamiajes de vidrio bioactivo y método de fabricación - Google Patents
Andamiajes de vidrio bioactivo y método de fabricación Download PDFInfo
- Publication number
- ES2924235T3 ES2924235T3 ES13750831T ES13750831T ES2924235T3 ES 2924235 T3 ES2924235 T3 ES 2924235T3 ES 13750831 T ES13750831 T ES 13750831T ES 13750831 T ES13750831 T ES 13750831T ES 2924235 T3 ES2924235 T3 ES 2924235T3
- Authority
- ES
- Spain
- Prior art keywords
- glass
- fibers
- beads
- scaffold
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000005313 bioactive glass Substances 0.000 title claims description 30
- 238000004519 manufacturing process Methods 0.000 title description 2
- 239000011521 glass Substances 0.000 claims abstract description 67
- 239000011324 bead Substances 0.000 claims abstract description 52
- 239000002245 particle Substances 0.000 claims abstract description 26
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 19
- 210000004872 soft tissue Anatomy 0.000 claims abstract description 9
- 239000000835 fiber Substances 0.000 claims description 56
- 239000000203 mixture Substances 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 16
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 230000009477 glass transition Effects 0.000 claims description 9
- 239000011148 porous material Substances 0.000 claims description 8
- 239000001301 oxygen Substances 0.000 claims description 7
- 229910052760 oxygen Inorganic materials 0.000 claims description 7
- 239000001294 propane Substances 0.000 claims description 7
- 239000003365 glass fiber Substances 0.000 claims description 5
- 238000002844 melting Methods 0.000 claims description 5
- 230000008018 melting Effects 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 2
- 239000006060 molten glass Substances 0.000 claims description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 2
- 239000002407 tissue scaffold Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 abstract description 18
- 239000000919 ceramic Substances 0.000 abstract description 6
- 239000007787 solid Substances 0.000 abstract description 5
- 210000004204 blood vessel Anatomy 0.000 abstract description 3
- 239000002241 glass-ceramic Substances 0.000 abstract description 3
- 238000011069 regeneration method Methods 0.000 abstract description 3
- 230000008467 tissue growth Effects 0.000 abstract description 3
- 238000001727 in vivo Methods 0.000 abstract description 2
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 230000008929 regeneration Effects 0.000 abstract description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 16
- 239000000463 material Substances 0.000 description 14
- 238000010438 heat treatment Methods 0.000 description 11
- 239000008188 pellet Substances 0.000 description 11
- 210000001519 tissue Anatomy 0.000 description 11
- 238000002425 crystallisation Methods 0.000 description 10
- 238000005245 sintering Methods 0.000 description 10
- 230000008025 crystallization Effects 0.000 description 9
- 239000000377 silicon dioxide Substances 0.000 description 8
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 7
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 239000003513 alkali Substances 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 239000007943 implant Substances 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 230000000399 orthopedic effect Effects 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 239000001506 calcium phosphate Substances 0.000 description 3
- 229910000389 calcium phosphate Inorganic materials 0.000 description 3
- 235000011010 calcium phosphates Nutrition 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 230000006911 nucleation Effects 0.000 description 3
- 238000010899 nucleation Methods 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000005368 silicate glass Substances 0.000 description 3
- 230000017423 tissue regeneration Effects 0.000 description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 3
- -1 45S5 and S53P4 Chemical class 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- CPLXHLVBOLITMK-UHFFFAOYSA-N Magnesium oxide Chemical compound [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical group [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 229910000287 alkaline earth metal oxide Inorganic materials 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 239000005312 bioglass Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 239000004568 cement Substances 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012681 fiber drawing Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- CHWRSCGUEQEHOH-UHFFFAOYSA-N potassium oxide Chemical compound [O-2].[K+].[K+] CHWRSCGUEQEHOH-UHFFFAOYSA-N 0.000 description 2
- 229910001950 potassium oxide Inorganic materials 0.000 description 2
- 238000007669 thermal treatment Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910011255 B2O3 Inorganic materials 0.000 description 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000004031 devitrification Methods 0.000 description 1
- JKWMSGQKBLHBQQ-UHFFFAOYSA-N diboron trioxide Chemical compound O=BOB=O JKWMSGQKBLHBQQ-UHFFFAOYSA-N 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000007496 glass forming Methods 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000000395 magnesium oxide Substances 0.000 description 1
- 230000005541 medical transmission Effects 0.000 description 1
- 239000011049 pearl Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B29/00—Reheating glass products for softening or fusing their surfaces; Fire-polishing; Fusing of margins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/07—Stiffening bandages
- A61L15/08—Stiffening bandages containing inorganic materials, e.g. plaster of Paris
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0036—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B19/00—Other methods of shaping glass
- C03B19/06—Other methods of shaping glass by sintering, e.g. by cold isostatic pressing of powders and subsequent sintering, by hot pressing of powders, by sintering slurries or dispersions not undergoing a liquid phase reaction
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B19/00—Other methods of shaping glass
- C03B19/09—Other methods of shaping glass by fusing powdered glass in a shaping mould
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B19/00—Other methods of shaping glass
- C03B19/10—Forming beads
- C03B19/108—Forming porous, sintered or foamed beads
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B32/00—Thermal after-treatment of glass products not provided for in groups C03B19/00, C03B25/00 - C03B31/00 or C03B37/00, e.g. crystallisation, eliminating gas inclusions or other impurities; Hot-pressing vitrified, non-porous, shaped glass products
- C03B32/02—Thermal crystallisation, e.g. for crystallising glass bodies into glass-ceramic articles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P40/00—Technologies relating to the processing of minerals
- Y02P40/50—Glass production, e.g. reusing waste heat during processing or shaping
- Y02P40/57—Improving the yield, e-g- reduction of reject rates
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Inorganic Chemistry (AREA)
- Ceramic Engineering (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Hematology (AREA)
- Materials For Medical Uses (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2013/036418 WO2014168631A1 (en) | 2013-04-12 | 2013-04-12 | Bioactive glass scaffolds, and method of making |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2924235T3 true ES2924235T3 (es) | 2022-10-05 |
Family
ID=51689886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13750831T Active ES2924235T3 (es) | 2013-04-12 | 2013-04-12 | Andamiajes de vidrio bioactivo y método de fabricación |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2984047B1 (https=) |
| JP (1) | JP5982730B2 (https=) |
| KR (1) | KR101677066B1 (https=) |
| CN (1) | CN104334503B (https=) |
| AU (1) | AU2013221955B2 (https=) |
| ES (1) | ES2924235T3 (https=) |
| MX (1) | MX356872B (https=) |
| WO (1) | WO2014168631A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2988615C (en) | 2014-06-09 | 2023-08-08 | The Royal Institution For The Advancement Of Learning/Mcgill University | Borate-glass biomaterials |
| GB201415005D0 (en) * | 2014-08-22 | 2014-10-08 | Univ Nottingham | Porous and non-pourous bodies |
| US10492921B2 (en) | 2015-04-29 | 2019-12-03 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with arched bone contacting elements |
| US10449051B2 (en) | 2015-04-29 | 2019-10-22 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with curved bone contacting elements |
| CN110946681B (zh) | 2015-04-29 | 2021-12-24 | 肌肉骨骼科学教育研究所有限公司 | 线圈状的植入物和系统及其使用方法 |
| US10709570B2 (en) | 2015-04-29 | 2020-07-14 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with a diagonal insertion axis |
| CN106913908B (zh) * | 2015-12-25 | 2020-05-26 | 北京瑞健高科生物科技有限公司 | 一种具有结构记忆特性的细胞生长支架 |
| US10478312B2 (en) | 2016-10-25 | 2019-11-19 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with protected fusion zones |
| US11033394B2 (en) | 2016-10-25 | 2021-06-15 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with multi-layer bone interfacing lattice |
| US10357377B2 (en) | 2017-03-13 | 2019-07-23 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with bone contacting elements having helical and undulating planar geometries |
| US10512549B2 (en) | 2017-03-13 | 2019-12-24 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with structural members arranged around a ring |
| EP4445922A3 (en) * | 2017-07-31 | 2024-12-04 | KCI USA, Inc. | Bioresorbable dressing with structural support |
| US10744001B2 (en) | 2017-11-21 | 2020-08-18 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with improved bone contact |
| US10940015B2 (en) | 2017-11-21 | 2021-03-09 | Institute for Musculoskeletal Science and Education, Ltd. | Implant with improved flow characteristics |
| US10512495B2 (en) | 2017-12-28 | 2019-12-24 | Industrial Technology Research Institute | Method for fabricating medical device and applications thereof |
| TWI647032B (zh) * | 2017-12-28 | 2019-01-11 | 財團法人工業技術研究院 | 醫療元件的製作方法及其應用 |
| DE102018114946B3 (de) | 2018-06-21 | 2019-04-25 | Klinikum Nürnberg Medical School GmbH | Bioaktiver Träger |
| DE102019124879B4 (de) | 2019-08-03 | 2026-03-26 | Klinikum Nürnberg Medical School GmbH | Bioaktiver Träger |
| CN114455834B (zh) * | 2022-01-17 | 2023-03-21 | 华南理工大学 | 一种高强度生物活性玻璃支架及其3d打印方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2935198C2 (de) * | 1979-08-31 | 1981-12-24 | Heraeus Quarzschmelze Gmbh, 6450 Hanau | Verfahren zur werkzeugfreien Herstellung von porösen Formkörpern aus Quarzglas und Verwendung dieser Formkörper |
| FR2566384B1 (fr) * | 1984-06-21 | 1986-09-05 | Saint Gobain Vitrage | Perfectionnements aux techniques de production de microspheres en verre |
| US4867931A (en) * | 1986-02-10 | 1989-09-19 | Materials Technology Corporation | Methods for producing fiber reinforced microspheres made from dispersed particle compositions |
| WO1997016384A1 (en) * | 1995-11-01 | 1997-05-09 | Minnesota Mining And Manufacturing Company | Methods of making fused particulates by flame fusion |
| US6254981B1 (en) * | 1995-11-02 | 2001-07-03 | Minnesota Mining & Manufacturing Company | Fused glassy particulates obtained by flame fusion |
| WO2001003709A1 (en) * | 1999-07-08 | 2001-01-18 | Cap Biotechnology, Inc. | Calcium-containing structures and methods of making and using the same |
| US20020139147A1 (en) * | 2001-01-30 | 2002-10-03 | Janas Victor F. | Glass scaffolds with controlled resorption rates and methods for making same |
| JP2008545866A (ja) * | 2005-06-10 | 2008-12-18 | チバ ホールディング インコーポレーテッド | プラズマトーチを使用する粒子の処理方法 |
| JP4854024B2 (ja) * | 2006-04-04 | 2012-01-11 | コバレントマテリアル株式会社 | 多孔体 |
| WO2009012455A1 (en) * | 2007-07-18 | 2009-01-22 | Oxane Materials, Inc. | Proppants with carbide and/or nitride phases |
| US8353966B2 (en) * | 2009-01-15 | 2013-01-15 | The Curators Of The University Of Missouri | Scaffold for bone and tissue repair in mammals |
| IN2012DN01107A (https=) * | 2009-07-10 | 2015-04-10 | Bio2 Technologies Inc | |
| US8481066B2 (en) * | 2009-07-16 | 2013-07-09 | The Curators Of The University Of Missouri | Scaffold for tissue regeneration in mammals |
| US8287896B2 (en) * | 2010-01-06 | 2012-10-16 | The Curators Of The University Of Missouri | Scaffolds with trace element for tissue regeneration in mammals |
| US8337875B2 (en) * | 2009-07-16 | 2012-12-25 | The Curators Of The University Of Missouri | Controlling vessel growth and directionality in mammals and implantable material |
| JP5721712B2 (ja) * | 2009-07-16 | 2015-05-20 | ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリＴｈｅ Ｃｕｒａｔｏｒｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｓｓｏｕｒｉ | 哺乳類の組織再生用の微量元素含有スキャフォールド |
| US8673018B2 (en) * | 2010-02-05 | 2014-03-18 | AMx Tek LLC | Methods of using water-soluble inorganic compounds for implants |
| US20120219635A1 (en) * | 2010-05-06 | 2012-08-30 | Bio2 Technologies, Inc. | Devices and Methods for Tissue Engineering |
| EP2619154A4 (en) * | 2010-09-21 | 2015-11-25 | Oxane Materials Inc | LIGHT SUPPORT OF IMPROVED STRENGTH AND METHOD FOR THE PRODUCTION THEREOF |
| PT105617A (pt) * | 2011-04-05 | 2012-10-08 | Univ Aveiro | Composição de vidros bioactivos, sua utilização e respectivo método de obtenção |
| CA2840235C (en) * | 2011-07-13 | 2017-11-14 | Oxane Materials, Inc. | Low surface friction proppants |
| US8449904B1 (en) * | 2012-03-26 | 2013-05-28 | Mosci, Corp. | Bioactive glass scaffolds, and method of making |
-
2013
- 2013-04-12 EP EP13750831.3A patent/EP2984047B1/en active Active
- 2013-04-12 KR KR1020147001206A patent/KR101677066B1/ko active Active
- 2013-04-12 AU AU2013221955A patent/AU2013221955B2/en active Active
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| CN104334503A (zh) | 2015-02-04 |
| AU2013221955B2 (en) | 2017-06-22 |
| AU2013221955A1 (en) | 2014-10-30 |
| JP2015520636A (ja) | 2015-07-23 |
| JP5982730B2 (ja) | 2016-08-31 |
| MX356872B (es) | 2018-06-18 |
| EP2984047B1 (en) | 2022-06-15 |
| MX2013009806A (es) | 2015-05-14 |
| KR20150008036A (ko) | 2015-01-21 |
| EP2984047A4 (en) | 2017-01-18 |
| CN104334503B (zh) | 2017-03-01 |
| WO2014168631A1 (en) | 2014-10-16 |
| KR101677066B1 (ko) | 2016-11-17 |
| EP2984047A1 (en) | 2016-02-17 |
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