ES2912465T3 - Compuestos y métodos para modular la tirosina quinasa de Bruton - Google Patents
Compuestos y métodos para modular la tirosina quinasa de Bruton Download PDFInfo
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- ES2912465T3 ES2912465T3 ES17764260T ES17764260T ES2912465T3 ES 2912465 T3 ES2912465 T3 ES 2912465T3 ES 17764260 T ES17764260 T ES 17764260T ES 17764260 T ES17764260 T ES 17764260T ES 2912465 T3 ES2912465 T3 ES 2912465T3
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Landscapes
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| KR102384924B1 (ko) * | 2017-07-12 | 2022-04-08 | 주식회사 대웅제약 | 신규한 1h-피라졸로피리딘 유도체 및 이를 포함하는 약학 조성물 |
| CN108191871B (zh) * | 2018-01-02 | 2020-02-18 | 成都倍特药业有限公司 | 新型布鲁顿酪氨酸激酶抑制剂及其制备方法和应用 |
| TWI767148B (zh) * | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| CN111662232B (zh) * | 2019-03-06 | 2022-08-02 | 中国科学院上海药物研究所 | 具有2h-吲唑结构的小分子化合物及其合成和应用 |
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| CN114437078A (zh) * | 2020-11-03 | 2022-05-06 | 海思科医药集团股份有限公司 | 一种降解btk的氘代物及其在医药上的应用 |
| CN117377675A (zh) * | 2021-06-01 | 2024-01-09 | 正大天晴药业集团股份有限公司 | 含有并环或螺环的布鲁顿酪氨酸激酶降解剂 |
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|---|---|---|---|---|
| RU2001129155A (ru) * | 1999-03-26 | 2003-08-10 | Еро-Сельтик С.А. (Lu) | Соединения с арильными заместителями (варианты), фармацевтическая композиция и способ лечения расстройства, чувствительного к блокаде натриевых каналов у млекопитающего, способ лечения, профилактики различных заболеваний или уменьшения интенсивности гибели или потери нейронов (варианты), способ облегчения или предупреждения эпилептических припадков у животного (варианты), соединение - радиоактивный лиганд для участка связывания в натриевом канале |
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-
2017
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- 2017-03-10 US US16/083,409 patent/US10870652B2/en active Active
- 2017-03-10 AU AU2017230098A patent/AU2017230098B2/en active Active
- 2017-03-10 WO PCT/US2017/021966 patent/WO2017156495A1/en not_active Ceased
- 2017-03-10 EP EP17764260.0A patent/EP3426637B1/en active Active
- 2017-03-10 CN CN202210903642.7A patent/CN115746000A/zh active Pending
- 2017-03-10 CA CA3017567A patent/CA3017567A1/en active Pending
- 2017-03-10 CN CN201780028799.7A patent/CN109071455B/zh active Active
- 2017-03-10 JP JP2018547964A patent/JP6972002B2/ja active Active
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- 2017-03-10 PL PL17764260T patent/PL3426637T3/pl unknown
- 2017-03-10 KR KR1020187029381A patent/KR102416971B1/ko active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| US10870652B2 (en) | 2020-12-22 |
| JP2019507793A (ja) | 2019-03-22 |
| JP6972002B2 (ja) | 2021-11-24 |
| WO2017156495A1 (en) | 2017-09-14 |
| KR102416971B1 (ko) | 2022-07-04 |
| EP3426637A1 (en) | 2019-01-16 |
| IL261583A (en) | 2018-10-31 |
| ZA201805951B (en) | 2020-12-23 |
| PL3426637T3 (pl) | 2022-05-30 |
| NZ745927A (en) | 2024-05-31 |
| MX388026B (es) | 2025-03-19 |
| EP3426637A4 (en) | 2019-09-18 |
| MX2018010971A (es) | 2019-03-28 |
| CN109071455B (zh) | 2022-08-02 |
| EP3426637B1 (en) | 2022-02-09 |
| US20190106423A1 (en) | 2019-04-11 |
| CA3017567A1 (en) | 2017-09-14 |
| KR20180133415A (ko) | 2018-12-14 |
| CN109071455A (zh) | 2018-12-21 |
| US11306099B1 (en) | 2022-04-19 |
| AU2017230098A1 (en) | 2018-09-20 |
| AU2017230098B2 (en) | 2021-03-25 |
| WO2017156495A8 (en) | 2018-09-27 |
| CN115746000A (zh) | 2023-03-07 |
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