ES2904317T3 - Dinucleótidos cíclicos como agentes anticancerosos - Google Patents
Dinucleótidos cíclicos como agentes anticancerosos Download PDFInfo
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- ES2904317T3 ES2904317T3 ES18766543T ES18766543T ES2904317T3 ES 2904317 T3 ES2904317 T3 ES 2904317T3 ES 18766543 T ES18766543 T ES 18766543T ES 18766543 T ES18766543 T ES 18766543T ES 2904317 T3 ES2904317 T3 ES 2904317T3
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- nra1ra1
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- acceptable salt
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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| KR20200098511A (ko) | 2017-11-10 | 2020-08-20 | 다케다 야쿠힌 고교 가부시키가이샤 | Sting 조절제 화합물, 및 제조 및 사용 방법 |
| EP3728283B1 (en) | 2017-12-20 | 2023-11-22 | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. | 3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| WO2019123339A1 (en) | 2017-12-20 | 2019-06-27 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
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| US10519187B2 (en) | 2018-02-13 | 2019-12-31 | Bristol-Myers Squibb Company | Cyclic dinucleotides as anticancer agents |
| ES2980374T3 (es) * | 2018-03-08 | 2024-10-01 | Bristol Myers Squibb Co | Dinucleótidos cíclicos como agentes anticancerosos |
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| CN107849084B (zh) | 2015-12-03 | 2021-09-14 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为sting调节剂的环状嘌呤二核苷酸 |
| DE212016000029U1 (de) * | 2015-12-07 | 2017-07-30 | Opi Vi - Ip Holdco Llc | Zusammensetzungen von Antikörperkonstrukt-Agonist-Konjugaten |
| US20180369268A1 (en) | 2015-12-16 | 2018-12-27 | Aduro Biotech, Inc. | Methods for identifying inhibitors of "stimulator of interferon gene"- dependent interferon production |
| US10723756B2 (en) * | 2016-01-11 | 2020-07-28 | Innate Tumor Immunity Inc. | Cyclic dinucleotides for treating conditions associated with STING activity such as cancer |
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2018
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- 2018-08-30 EP EP18766543.5A patent/EP3676279B1/en active Active
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| KR102674630B1 (ko) | 2024-06-11 |
| JP2020532529A (ja) | 2020-11-12 |
| KR20200042938A (ko) | 2020-04-24 |
| EP3676279A1 (en) | 2020-07-08 |
| EP3676279B1 (en) | 2021-12-01 |
| US10953032B2 (en) | 2021-03-23 |
| CN111051328A (zh) | 2020-04-21 |
| JP7208225B2 (ja) | 2023-01-18 |
| US20200253997A1 (en) | 2020-08-13 |
| WO2019046500A1 (en) | 2019-03-07 |
| CN111051328B (zh) | 2023-11-03 |
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