ES2848392T3 - Dispositivo para ablación de venas - Google Patents
Dispositivo para ablación de venas Download PDFInfo
- Publication number
- ES2848392T3 ES2848392T3 ES09718042T ES09718042T ES2848392T3 ES 2848392 T3 ES2848392 T3 ES 2848392T3 ES 09718042 T ES09718042 T ES 09718042T ES 09718042 T ES09718042 T ES 09718042T ES 2848392 T3 ES2848392 T3 ES 2848392T3
- Authority
- ES
- Spain
- Prior art keywords
- intravascular irritation
- vein
- intravascular
- irritation element
- irritating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000003462 vein Anatomy 0.000 title claims abstract description 151
- 238000002679 ablation Methods 0.000 title description 11
- 230000007794 irritation Effects 0.000 claims abstract description 124
- 239000000126 substance Substances 0.000 claims description 29
- 238000000605 extraction Methods 0.000 claims description 19
- 239000003229 sclerosing agent Substances 0.000 claims description 19
- 239000008280 blood Substances 0.000 claims description 17
- 210000004369 blood Anatomy 0.000 claims description 17
- 239000002085 irritant Substances 0.000 claims description 14
- 231100000021 irritant Toxicity 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 6
- 239000012781 shape memory material Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 description 28
- 238000011282 treatment Methods 0.000 description 22
- 230000006378 damage Effects 0.000 description 11
- 206010046996 Varicose vein Diseases 0.000 description 9
- 239000000463 material Substances 0.000 description 8
- 210000003752 saphenous vein Anatomy 0.000 description 7
- 230000007246 mechanism Effects 0.000 description 6
- 238000007790 scraping Methods 0.000 description 6
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 6
- 208000027185 varicose disease Diseases 0.000 description 6
- 230000008014 freezing Effects 0.000 description 4
- 238000007710 freezing Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 230000005855 radiation Effects 0.000 description 4
- 230000001680 brushing effect Effects 0.000 description 3
- 210000004013 groin Anatomy 0.000 description 3
- 238000006748 scratching Methods 0.000 description 3
- 230000002393 scratching effect Effects 0.000 description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
- 206010053567 Coagulopathies Diseases 0.000 description 2
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- 210000003423 ankle Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000035602 clotting Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 229920002674 hyaluronan Polymers 0.000 description 2
- 229960003160 hyaluronic acid Drugs 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000007632 sclerotherapy Methods 0.000 description 2
- 229960000776 sodium tetradecyl sulfate Drugs 0.000 description 2
- UPUIQOIQVMNQAP-UHFFFAOYSA-M sodium;tetradecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O UPUIQOIQVMNQAP-UHFFFAOYSA-M 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 201000002282 venous insufficiency Diseases 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 description 1
- 108010006654 Bleomycin Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 241001427559 Collembola Species 0.000 description 1
- 229920001363 Polidocanol Polymers 0.000 description 1
- 206010040829 Skin discolouration Diseases 0.000 description 1
- 206010062696 Spider vein Diseases 0.000 description 1
- 108010023197 Streptokinase Proteins 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229960001561 bleomycin Drugs 0.000 description 1
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 208000031066 hyperpigmentation of the skin Diseases 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002608 intravascular ultrasound Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229940020573 plavix Drugs 0.000 description 1
- ONJQDTZCDSESIW-UHFFFAOYSA-N polidocanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ONJQDTZCDSESIW-UHFFFAOYSA-N 0.000 description 1
- 229960002226 polidocanol Drugs 0.000 description 1
- 210000003513 popliteal vein Anatomy 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 229960005202 streptokinase Drugs 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000013151 thrombectomy Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 201000004822 varicocele Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000002073 venous valve Anatomy 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00008—Vein tendon strippers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
- A61B17/12186—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00778—Operations on blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B2017/320004—Surgical cutting instruments abrasive
- A61B2017/320012—Brushes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B2017/320741—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions for stripping the intima or the internal plaque from a blood vessel, e.g. for endarterectomy
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3297808P | 2008-03-02 | 2008-03-02 | |
| PCT/IL2009/000241 WO2009109967A1 (en) | 2008-03-02 | 2009-03-02 | Method and device for vein ablation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2848392T3 true ES2848392T3 (es) | 2021-08-09 |
Family
ID=40638126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09718042T Active ES2848392T3 (es) | 2008-03-02 | 2009-03-02 | Dispositivo para ablación de venas |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10159472B2 (enExample) |
| EP (1) | EP2257224B1 (enExample) |
| JP (1) | JP5527744B2 (enExample) |
| ES (1) | ES2848392T3 (enExample) |
| PL (1) | PL2257224T3 (enExample) |
| WO (1) | WO2009109967A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10765479B2 (en) | 2003-09-30 | 2020-09-08 | Biolitec Unternehmensbeteiligungs Ii Ag | Method for treatment of varicocele |
| PL2257224T3 (pl) | 2008-03-02 | 2021-05-04 | V.V.T. Med Ltd. | Urządzenie do ablacji żył |
| US9585667B2 (en) * | 2010-11-15 | 2017-03-07 | Vascular Insights Llc | Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein |
| US20120109191A1 (en) * | 2011-12-13 | 2012-05-03 | Vascular Insights Llc | Adhesive-based varicose vein treatment |
| EP3054856B1 (en) | 2013-10-13 | 2020-12-09 | V.V.T. Med Ltd. | Device for synchronized injection and aspiration |
| EP3054857B1 (en) | 2013-10-13 | 2020-09-09 | V.V.T. Med Ltd. | Vein ablation device |
| ES2831975T3 (es) | 2013-10-13 | 2021-06-09 | Vvt Medical Ltd | Dispositivo y método de formación de espuma |
| US20160030023A1 (en) * | 2014-07-31 | 2016-02-04 | Terumo Kabushiki Kaisha | Method for treating varicose veins and intraluminal device used in such method |
| US20160030068A1 (en) * | 2014-07-31 | 2016-02-04 | Terumo Kabushiki Kaisha | Method for treating varicose veins and intraluminal device used in such method |
| US20160030719A1 (en) * | 2014-07-31 | 2016-02-04 | Terumo Kabushiki Kaisha | Method for treating varicose veins and intraluminal device used in such method |
| PL228142B1 (pl) * | 2014-10-17 | 2018-02-28 | Balton Społka Z Ograniczoną Odpowiedzialnością | Kateter zawierajacy element tnacy |
| GB201511595D0 (en) | 2014-12-23 | 2015-08-19 | Whiteley Mark | Medical device for treating a vein |
| EP3135206B1 (de) * | 2015-08-31 | 2020-01-15 | Gefässpraxis Dr. Erpen AG | Vorrichtung zur behandlung der varikose |
| KR20190007447A (ko) * | 2016-05-13 | 2019-01-22 | 스위스 브이엑스 베넨쎄라피 운트 포르스청 게엠베하 | 혈관의 일시적 폐색을 위한 비-이식형 장치 및 이의 사용법 |
| US10580131B2 (en) | 2017-02-23 | 2020-03-03 | Zebra Medical Vision Ltd. | Convolutional neural network for segmentation of medical anatomical images |
| US11690645B2 (en) | 2017-05-03 | 2023-07-04 | Medtronic Vascular, Inc. | Tissue-removing catheter |
| US11051842B2 (en) | 2017-05-03 | 2021-07-06 | Medtronic Vascular, Inc. | Tissue-removing catheter with guidewire isolation liner |
| IE87658B1 (en) | 2018-05-18 | 2025-09-24 | Nat Univ Ireland Galway | A device for denuding a body lumen |
| CN118697424A (zh) | 2018-11-16 | 2024-09-27 | 美敦力瓦斯科尔勒公司 | 组织去除导管 |
| US11819236B2 (en) | 2019-05-17 | 2023-11-21 | Medtronic Vascular, Inc. | Tissue-removing catheter |
| CN111167000A (zh) * | 2019-12-31 | 2020-05-19 | 李雷 | 脉管封闭装置 |
| CN111228640A (zh) * | 2020-01-10 | 2020-06-05 | 李雷 | 脉管封闭装置 |
| IT202000025918A1 (it) * | 2020-10-30 | 2022-04-30 | I Vasc Srl | Dispositivo vascolare intraluminale, particolarmente per scleroterapia, e metodo |
| US11696793B2 (en) * | 2021-03-19 | 2023-07-11 | Crossfire Medical Inc | Vascular ablation |
| CN114748135A (zh) * | 2022-03-25 | 2022-07-15 | 复旦大学附属中山医院 | 一种用于动脉内膜碎屑清除的双头花生米状装置 |
| US20250339167A1 (en) * | 2022-04-07 | 2025-11-06 | Clearstream Technologies Limited | Venous ablation device |
| US20240149020A1 (en) | 2022-11-04 | 2024-05-09 | Controlled Delivery Systems, Inc. | Catheters for the aspiration controlled delivery of closure agents |
| AU2023371657A1 (en) | 2022-11-04 | 2025-05-15 | Solvein Inc. | Catheters and related methods for aspiration and controlled delivery of closure agents |
| WO2024240328A1 (en) * | 2023-05-22 | 2024-11-28 | Clearstream Technologies Limited | Medical device for insertion into and treatment of a vein |
| WO2025073343A1 (en) * | 2023-10-02 | 2025-04-10 | Clearstream Technologies Limited | Venous ablation system |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5108419A (en) * | 1990-08-16 | 1992-04-28 | Evi Corporation | Endovascular filter and method for use thereof |
| US5370653A (en) * | 1993-07-22 | 1994-12-06 | Micro Therapeutics, Inc. | Thrombectomy method and apparatus |
| US6022336A (en) * | 1996-05-20 | 2000-02-08 | Percusurge, Inc. | Catheter system for emboli containment |
| US5730734A (en) * | 1996-11-14 | 1998-03-24 | Scimed Life Systems, Inc. | Catheter systems with interchangeable parts |
| US6394996B1 (en) * | 1997-01-07 | 2002-05-28 | C. R. Bard, Inc. | System for aspirating and irrigating tract wounds |
| US6168579B1 (en) * | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
| US6402745B1 (en) | 2000-02-23 | 2002-06-11 | Peter J. Wilk | Intravenous whip electrode for vein ablation |
| US20010031981A1 (en) * | 2000-03-31 | 2001-10-18 | Evans Michael A. | Method and device for locating guidewire and treating chronic total occlusions |
| US6755813B2 (en) * | 2001-11-20 | 2004-06-29 | Cleveland Clinic Foundation | Apparatus and method for performing thrombolysis |
| US7862575B2 (en) | 2003-05-21 | 2011-01-04 | Yale University | Vascular ablation apparatus and method |
| US7326206B2 (en) | 2004-01-16 | 2008-02-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Conforming-electrode catheter and method for ablation |
| DE102004040868A1 (de) * | 2004-08-23 | 2006-03-09 | Miloslavski, Elina | Vorrichtung zur Entfernung von Thromben |
| GB0512073D0 (en) | 2005-06-14 | 2005-07-20 | Vallabhaneni Srinivasa R | Device for use in treatment of varicose veins |
| PL2257224T3 (pl) | 2008-03-02 | 2021-05-04 | V.V.T. Med Ltd. | Urządzenie do ablacji żył |
-
2009
- 2009-03-02 PL PL09718042T patent/PL2257224T3/pl unknown
- 2009-03-02 WO PCT/IL2009/000241 patent/WO2009109967A1/en not_active Ceased
- 2009-03-02 EP EP09718042.6A patent/EP2257224B1/en active Active
- 2009-03-02 JP JP2010549253A patent/JP5527744B2/ja active Active
- 2009-03-02 ES ES09718042T patent/ES2848392T3/es active Active
- 2009-03-02 US US12/920,335 patent/US10159472B2/en active Active
-
2018
- 2018-12-23 US US16/231,523 patent/US11006935B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2257224A1 (en) | 2010-12-08 |
| US11006935B2 (en) | 2021-05-18 |
| US20190125322A1 (en) | 2019-05-02 |
| JP2011512983A (ja) | 2011-04-28 |
| US10159472B2 (en) | 2018-12-25 |
| WO2009109967A1 (en) | 2009-09-11 |
| EP2257224B1 (en) | 2020-11-04 |
| US20110046543A1 (en) | 2011-02-24 |
| PL2257224T3 (pl) | 2021-05-04 |
| JP5527744B2 (ja) | 2014-06-25 |
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