ES2831699T3 - Un carbonato de calcio morfo para el tratamiento de la mala absorción de calcio y los trastornos metabólicos óseos - Google Patents
Un carbonato de calcio morfo para el tratamiento de la mala absorción de calcio y los trastornos metabólicos óseos Download PDFInfo
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- ES2831699T3 ES2831699T3 ES12857932T ES12857932T ES2831699T3 ES 2831699 T3 ES2831699 T3 ES 2831699T3 ES 12857932 T ES12857932 T ES 12857932T ES 12857932 T ES12857932 T ES 12857932T ES 2831699 T3 ES2831699 T3 ES 2831699T3
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- 229940089617 risedronate Drugs 0.000 description 1
- 231100000279 safety data Toxicity 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000000849 selective androgen receptor modulator Substances 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 229940083542 sodium Drugs 0.000 description 1
- 229940045902 sodium stearyl fumarate Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229960004274 stearic acid Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- OGBMKVWORPGQRR-UMXFMPSGSA-N teriparatide Chemical compound C([C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CNC=N1 OGBMKVWORPGQRR-UMXFMPSGSA-N 0.000 description 1
- 229960005460 teriparatide Drugs 0.000 description 1
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- 230000035922 thirst Effects 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 229940056345 tums Drugs 0.000 description 1
- UONOETXJSWQNOL-UHFFFAOYSA-N tungsten carbide Chemical compound [W+]#[C-] UONOETXJSWQNOL-UHFFFAOYSA-N 0.000 description 1
- 229940045136 urea Drugs 0.000 description 1
- 230000036325 urinary excretion Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569805P | 2011-12-13 | 2011-12-13 | |
| US201261680721P | 2012-08-08 | 2012-08-08 | |
| PCT/IL2012/050521 WO2013088440A1 (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2831699T3 true ES2831699T3 (es) | 2021-06-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12857932T Active ES2831699T3 (es) | 2011-12-13 | 2012-12-13 | Un carbonato de calcio morfo para el tratamiento de la mala absorción de calcio y los trastornos metabólicos óseos |
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| Country | Link |
|---|---|
| US (2) | US10064890B2 (enExample) |
| EP (1) | EP2790710B1 (enExample) |
| JP (3) | JP2015500333A (enExample) |
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| CA (2) | CA3056570C (enExample) |
| DK (1) | DK2790710T3 (enExample) |
| ES (1) | ES2831699T3 (enExample) |
| IL (2) | IL233107B (enExample) |
| WO (1) | WO2013088440A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014213643A1 (en) * | 2013-02-11 | 2015-08-06 | Amorphical Ltd. | Amorphous calcium carbonate for accelerated bone growth |
| RU2694962C2 (ru) * | 2014-07-31 | 2019-07-18 | Аморфикал Лтд. | Капсулированные композиции аморфного карбоната кальция |
| US12121538B2 (en) | 2015-06-04 | 2024-10-22 | Amorphical Ltd. | Compositions of amorphous calcium carbonate for inhalation, sublingual or buccal administration |
| CN107921061A (zh) * | 2015-06-04 | 2018-04-17 | 艾玛菲克有限公司 | 用聚磷酸/聚磷酸酯/聚磷酸盐或双膦酸/双膦酸酯/双膦酸盐稳定的无定形碳酸钙 |
| JP2017032550A (ja) * | 2015-07-30 | 2017-02-09 | 大塚製薬株式会社 | 胃粘膜萎縮の有無を判定する方法 |
| KR20180109940A (ko) | 2016-01-18 | 2018-10-08 | 아모피컬 리미티드 | 세포 배양 배지용 보충물로서의 안정화된 무정형 탄산칼슘 |
| CA3011667C (en) * | 2016-01-18 | 2024-09-17 | Amorphical Ltd. | Stabilized amorphous calcium carbonate for the treatment of neurological or muscular diseases or conditions and infertility |
| US20230365935A1 (en) * | 2016-01-18 | 2023-11-16 | Amorphical Ltd. | Stabilized amorphous calcium carbonate as a supplement for cell culture media |
| JP6872680B2 (ja) * | 2016-03-22 | 2021-05-19 | 国立大学法人 宮崎大学 | カルシウム吸収促進剤 |
| JP7152785B2 (ja) * | 2016-10-25 | 2022-10-13 | アモーフィカル リミテッド． | 白血病治療のための非晶質炭酸カルシウム |
| CN110123836A (zh) * | 2019-05-20 | 2019-08-16 | 昆明朗盛生物科技有限公司 | 钙锌维生素d泛酸片的应用 |
| BR112022000281A2 (pt) | 2019-07-23 | 2022-02-22 | Amorphical Ltd | Carbonato de cálcio amorfo para aprimorar o desempenho atlético |
| EP4117685A4 (en) * | 2020-03-11 | 2024-03-20 | Amorphical Ltd. | AMORPHOUS CALCIUM CARBONATE FOR THE TREATMENT OF ACIDOSIS |
| WO2021226064A1 (en) * | 2020-05-04 | 2021-11-11 | University Of Louisville Research Foundation, Inc. | Artificial intelligence-based systems and methods for dosing of pharmacologic agents |
| US20230372554A1 (en) * | 2020-09-15 | 2023-11-23 | Oncoinvent As | Size controlled radiolabelled particles |
| JP7573310B2 (ja) * | 2022-02-28 | 2024-10-25 | 一般社団法人 Unical | ヒトによる経口摂取のためのカルシウム組成物 |
| JP2025535570A (ja) * | 2022-11-08 | 2025-10-24 | アモールフィカル リミテッド | 二酸化炭素の固定による非晶質炭酸カルシウムを調製するための方法 |
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| ATE82120T1 (de) * | 1987-08-28 | 1992-11-15 | Norwich Eaton Pharma | Kalziumzusaetze. |
| GB2217988B (en) * | 1988-04-11 | 1992-04-01 | Gould Leonard W | Regimen for increasing bone density in humans |
| AU1366697A (en) | 1995-12-26 | 1997-07-28 | Holomed Aps | A method and system for generating an x-ray image |
| JPH10236957A (ja) | 1997-02-24 | 1998-09-08 | Bankaku Souhonpo:Kk | 骨粗鬆症の改善剤 |
| SE9702401D0 (sv) * | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| JP2003292453A (ja) * | 2002-04-02 | 2003-10-15 | Asahi Kasei Corp | 骨疾患治療用医薬複合剤 |
| US7267832B2 (en) * | 2004-02-18 | 2007-09-11 | Kraft Foods Holdings, Inc. | Amorphous water-soluble calcium citrate salts and method of making and using same |
| AU2005247198B2 (en) * | 2004-05-26 | 2011-09-22 | Ben-Gurion University Of The Negev Research And Development Authority | Orally-administrable compositions comprising stable amorphous calcium carbonate |
| US20070041506A1 (en) | 2005-08-22 | 2007-02-22 | Michelle Bottino | Digital sensor holder |
| GB0522045D0 (en) * | 2005-10-28 | 2005-12-07 | Novartis Ag | Pharmaceutical compositions |
| IL178495A (en) | 2006-10-05 | 2014-12-31 | Univ Ben Gurion | Use of cancerous gastric components or artificial calcium containing carbonate, chitin and polypeptide preparations to treat calcium metabolism-related or calcium-signaling conditions |
| ES2393041T3 (es) * | 2007-10-22 | 2012-12-18 | Amorphical Ltd. | Carbonato de calcio amorfo estable que comprende aminoácidos fosforilados |
| WO2009087553A1 (en) | 2008-01-02 | 2009-07-16 | Aurobindo Pharma Limited | Kits for administering bisphosphonates |
| CN101314031A (zh) | 2008-07-14 | 2008-12-03 | 王冰 | 一种改善骨营养的制剂 |
| WO2010045558A1 (en) * | 2008-10-17 | 2010-04-22 | Fresenius Medical Care Holdings, Inc. | Method of determining a phosphorus binder dosage for a dialysis patient |
| CN102085356B (zh) * | 2010-12-28 | 2013-02-27 | 北京同仁堂健康药业股份有限公司 | 一种用于增加骨密度的组合物及其制备方法 |
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- 2012-12-13 WO PCT/IL2012/050521 patent/WO2013088440A1/en not_active Ceased
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- 2012-12-13 CA CA2859122A patent/CA2859122C/en active Active
- 2012-12-13 US US14/364,992 patent/US10064890B2/en active Active
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- 2012-12-13 JP JP2014546729A patent/JP2015500333A/ja active Pending
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2014
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2017
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2018
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Also Published As
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| EP2790710B1 (en) | 2020-08-26 |
| JP2018138591A (ja) | 2018-09-06 |
| CA3056570C (en) | 2022-04-19 |
| EP2790710A1 (en) | 2014-10-22 |
| IL274755A (en) | 2020-07-30 |
| WO2013088440A1 (en) | 2013-06-20 |
| CA2859122A1 (en) | 2013-06-20 |
| WO2013088440A8 (en) | 2013-08-01 |
| AU2012354056B2 (en) | 2017-10-05 |
| AU2020200704A1 (en) | 2020-02-20 |
| AU2017279824A1 (en) | 2018-01-25 |
| CN109568338A (zh) | 2019-04-05 |
| DK2790710T3 (da) | 2020-11-30 |
| JP2015500333A (ja) | 2015-01-05 |
| CN104114179A (zh) | 2014-10-22 |
| US20150056306A1 (en) | 2015-02-26 |
| IL274755B (en) | 2021-04-29 |
| IL233107B (en) | 2020-06-30 |
| US10064890B2 (en) | 2018-09-04 |
| US10688124B2 (en) | 2020-06-23 |
| CA2859122C (en) | 2019-11-05 |
| EP2790710A4 (en) | 2015-11-11 |
| US20190022133A1 (en) | 2019-01-24 |
| AU2012354056A1 (en) | 2014-07-10 |
| JP2019214631A (ja) | 2019-12-19 |
| AU2012354056A8 (en) | 2017-10-12 |
| IL233107A0 (en) | 2014-07-31 |
| CA3056570A1 (en) | 2013-06-20 |
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