IL233107B - Amorphous calcium carbonate for the treatment of poor calcium absorption and diseases with metabolism - Google Patents

Amorphous calcium carbonate for the treatment of poor calcium absorption and diseases with metabolism

Info

Publication number
IL233107B
IL233107B IL233107A IL23310714A IL233107B IL 233107 B IL233107 B IL 233107B IL 233107 A IL233107 A IL 233107A IL 23310714 A IL23310714 A IL 23310714A IL 233107 B IL233107 B IL 233107B
Authority
IL
Israel
Prior art keywords
treatment
bone disorders
malabsorption
metabolic bone
calcium
Prior art date
Application number
IL233107A
Other languages
English (en)
Hebrew (he)
Other versions
IL233107A0 (en
Inventor
Amir Sagi
Assaf Shechter
Galit Shaltiel-Gold
Michal Daniely
Meiron Oren
Original Assignee
Amorphical Ltd
Amir Sagi
Assaf Shechter
Shaltiel Gold Galit
Michal Daniely
Meiron Oren
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amorphical Ltd, Amir Sagi, Assaf Shechter, Shaltiel Gold Galit, Michal Daniely, Meiron Oren filed Critical Amorphical Ltd
Publication of IL233107A0 publication Critical patent/IL233107A0/en
Publication of IL233107B publication Critical patent/IL233107B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/612Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL233107A 2011-12-13 2014-06-12 Amorphous calcium carbonate for the treatment of poor calcium absorption and diseases with metabolism IL233107B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161569805P 2011-12-13 2011-12-13
US201261680721P 2012-08-08 2012-08-08
PCT/IL2012/050521 WO2013088440A1 (en) 2011-12-13 2012-12-13 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders

Publications (2)

Publication Number Publication Date
IL233107A0 IL233107A0 (en) 2014-07-31
IL233107B true IL233107B (en) 2020-06-30

Family

ID=48611949

Family Applications (2)

Application Number Title Priority Date Filing Date
IL233107A IL233107B (en) 2011-12-13 2014-06-12 Amorphous calcium carbonate for the treatment of poor calcium absorption and diseases with metabolism
IL274755A IL274755B (en) 2011-12-13 2020-05-18 Amorphous calcium carbonate for the treatment of poor calcium absorption and metabolic bone diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL274755A IL274755B (en) 2011-12-13 2020-05-18 Amorphous calcium carbonate for the treatment of poor calcium absorption and metabolic bone diseases

Country Status (10)

Country Link
US (2) US10064890B2 (enExample)
EP (1) EP2790710B1 (enExample)
JP (3) JP2015500333A (enExample)
CN (2) CN109568338A (enExample)
AU (3) AU2012354056B2 (enExample)
CA (2) CA2859122C (enExample)
DK (1) DK2790710T3 (enExample)
ES (1) ES2831699T3 (enExample)
IL (2) IL233107B (enExample)
WO (1) WO2013088440A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105007925A (zh) * 2013-02-11 2015-10-28 艾玛菲克有限公司 用于加速骨生长的无定形碳酸钙
AU2015294867B2 (en) * 2014-07-31 2019-07-11 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
US12121538B2 (en) 2015-06-04 2024-10-22 Amorphical Ltd. Compositions of amorphous calcium carbonate for inhalation, sublingual or buccal administration
CA2988060C (en) * 2015-06-04 2023-09-05 Amorphical Ltd. Amorphous calcium carbonate stabilized with polyphosphates or bisphosphonates
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
US20230365935A1 (en) * 2016-01-18 2023-11-16 Amorphical Ltd. Stabilized amorphous calcium carbonate as a supplement for cell culture media
JP6873389B2 (ja) 2016-01-18 2021-05-19 アモーフィカル リミテッド. 神経学的、筋肉、および不妊の疾患または症状の治療のための安定化無定形炭酸カルシウム
AU2017210259B2 (en) 2016-01-18 2022-11-03 Amorphical Ltd. Stabilized amorphous calcium carbonate as a supplement for cell culture media
JP6872680B2 (ja) * 2016-03-22 2021-05-19 国立大学法人 宮崎大学 カルシウム吸収促進剤
WO2018078616A1 (en) * 2016-10-25 2018-05-03 Amorphical Ltd Amorphous calcium carbonate for treating a leukemia
CN110123836A (zh) * 2019-05-20 2019-08-16 昆明朗盛生物科技有限公司 钙锌维生素d泛酸片的应用
KR20220038056A (ko) 2019-07-23 2022-03-25 아모피컬 리미티드 운동 수행능력을 개선시키기 위한 비정질 탄산칼슘
AU2021235449A1 (en) * 2020-03-11 2022-10-06 Amorphical Ltd. Amorphous calcium carbonate for treatment of acidosis
US20230223125A1 (en) * 2020-05-04 2023-07-13 University Of Louisville Research Foundation, Inc. Artificial intelligence-based systems and methods for dosing of pharmacologic agents
CN116367867A (zh) * 2020-09-15 2023-06-30 昂科因凡特公司 尺寸可控的放射性标记粒子
JP7573310B2 (ja) * 2022-02-28 2024-10-25 一般社団法人 Unical ヒトによる経口摂取のためのカルシウム組成物
WO2024100658A1 (en) * 2022-11-08 2024-05-16 Amorphical Ltd. Methods for preparing amorphous calcium carbonate by fixation of carbon dioxide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87452A (en) * 1987-08-28 1992-07-15 Norwich Eaton Pharma Calcium citrate malate and calcium supplements containing it
GB2217988B (en) * 1988-04-11 1992-04-01 Gould Leonard W Regimen for increasing bone density in humans
AU1366697A (en) 1995-12-26 1997-07-28 Holomed Aps A method and system for generating an x-ray image
JPH10236957A (ja) 1997-02-24 1998-09-08 Bankaku Souhonpo:Kk 骨粗鬆症の改善剤
SE9702401D0 (sv) * 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
JP2003292453A (ja) * 2002-04-02 2003-10-15 Asahi Kasei Corp 骨疾患治療用医薬複合剤
US7267832B2 (en) * 2004-02-18 2007-09-11 Kraft Foods Holdings, Inc. Amorphous water-soluble calcium citrate salts and method of making and using same
PL1758599T3 (pl) 2004-05-26 2014-04-30 Ben Gurion Univ Of The Negev Research And Development Authority Kompozycja do podania doustnego zawierająca stabilny amorficzny węglan wapnia
US20070041506A1 (en) 2005-08-22 2007-02-22 Michelle Bottino Digital sensor holder
GB0522045D0 (en) 2005-10-28 2005-12-07 Novartis Ag Pharmaceutical compositions
IL178495A (en) * 2006-10-05 2014-12-31 Univ Ben Gurion Use of cancerous gastric components or artificial calcium containing carbonate, chitin and polypeptide preparations to treat calcium metabolism-related or calcium-signaling conditions
CN101969962B (zh) * 2007-10-22 2014-10-22 艾玛菲克有限公司 包含磷酸化氨基酸、合成的磷酸化肽和胃石蛋白的稳定的无定形碳酸钙
WO2009087553A1 (en) 2008-01-02 2009-07-16 Aurobindo Pharma Limited Kits for administering bisphosphonates
CN101314031A (zh) 2008-07-14 2008-12-03 王冰 一种改善骨营养的制剂
WO2010045558A1 (en) * 2008-10-17 2010-04-22 Fresenius Medical Care Holdings, Inc. Method of determining a phosphorus binder dosage for a dialysis patient
CN102085356B (zh) * 2010-12-28 2013-02-27 北京同仁堂健康药业股份有限公司 一种用于增加骨密度的组合物及其制备方法

Also Published As

Publication number Publication date
US10688124B2 (en) 2020-06-23
CA2859122C (en) 2019-11-05
JP2015500333A (ja) 2015-01-05
IL233107A0 (en) 2014-07-31
DK2790710T3 (da) 2020-11-30
AU2012354056A1 (en) 2014-07-10
AU2012354056A8 (en) 2017-10-12
CA3056570A1 (en) 2013-06-20
US20190022133A1 (en) 2019-01-24
JP2018138591A (ja) 2018-09-06
EP2790710B1 (en) 2020-08-26
ES2831699T3 (es) 2021-06-09
WO2013088440A8 (en) 2013-08-01
EP2790710A4 (en) 2015-11-11
WO2013088440A1 (en) 2013-06-20
IL274755A (en) 2020-07-30
CN109568338A (zh) 2019-04-05
CA2859122A1 (en) 2013-06-20
CA3056570C (en) 2022-04-19
US10064890B2 (en) 2018-09-04
AU2020200704A1 (en) 2020-02-20
AU2012354056B2 (en) 2017-10-05
US20150056306A1 (en) 2015-02-26
EP2790710A1 (en) 2014-10-22
IL274755B (en) 2021-04-29
JP2019214631A (ja) 2019-12-19
AU2017279824A1 (en) 2018-01-25
CN104114179A (zh) 2014-10-22

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FF Patent granted