AU2012354056B2 - Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders - Google Patents

Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders Download PDF

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Publication number
AU2012354056B2
AU2012354056B2 AU2012354056A AU2012354056A AU2012354056B2 AU 2012354056 B2 AU2012354056 B2 AU 2012354056B2 AU 2012354056 A AU2012354056 A AU 2012354056A AU 2012354056 A AU2012354056 A AU 2012354056A AU 2012354056 B2 AU2012354056 B2 AU 2012354056B2
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AU
Australia
Prior art keywords
calcium
acc
subjects
bone
stabilizer
Prior art date
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AU2012354056A
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English (en)
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AU2012354056A8 (en
AU2012354056A1 (en
Inventor
Michal Daniely
Oren MEIRON
Amir Sagi
Galit SHALTIEL-GOLD
Assaf Shechter
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Amorphical Ltd
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Amorphical Ltd
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Publication date
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Publication of AU2012354056A1 publication Critical patent/AU2012354056A1/en
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Publication of AU2012354056B2 publication Critical patent/AU2012354056B2/en
Publication of AU2012354056A8 publication Critical patent/AU2012354056A8/en
Priority to AU2017279824A priority Critical patent/AU2017279824A1/en
Priority to AU2020200704A priority patent/AU2020200704A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU2012354056A 2011-12-13 2012-12-13 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders Active AU2012354056B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2017279824A AU2017279824A1 (en) 2011-12-13 2017-12-28 Amorphous Calcium Carbonate For the Treatment of Calcium Malabsorption and Metabolic Bone Disorders
AU2020200704A AU2020200704A1 (en) 2011-12-13 2020-01-31 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161569805P 2011-12-13 2011-12-13
US61/569,805 2011-12-13
US201261680721P 2012-08-08 2012-08-08
US61/680,721 2012-08-08
PCT/IL2012/050521 WO2013088440A1 (en) 2011-12-13 2012-12-13 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017279824A Division AU2017279824A1 (en) 2011-12-13 2017-12-28 Amorphous Calcium Carbonate For the Treatment of Calcium Malabsorption and Metabolic Bone Disorders

Publications (3)

Publication Number Publication Date
AU2012354056A1 AU2012354056A1 (en) 2014-07-10
AU2012354056B2 true AU2012354056B2 (en) 2017-10-05
AU2012354056A8 AU2012354056A8 (en) 2017-10-12

Family

ID=48611949

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2012354056A Active AU2012354056B2 (en) 2011-12-13 2012-12-13 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders
AU2017279824A Abandoned AU2017279824A1 (en) 2011-12-13 2017-12-28 Amorphous Calcium Carbonate For the Treatment of Calcium Malabsorption and Metabolic Bone Disorders
AU2020200704A Abandoned AU2020200704A1 (en) 2011-12-13 2020-01-31 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2017279824A Abandoned AU2017279824A1 (en) 2011-12-13 2017-12-28 Amorphous Calcium Carbonate For the Treatment of Calcium Malabsorption and Metabolic Bone Disorders
AU2020200704A Abandoned AU2020200704A1 (en) 2011-12-13 2020-01-31 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders

Country Status (10)

Country Link
US (2) US10064890B2 (enExample)
EP (1) EP2790710B1 (enExample)
JP (3) JP2015500333A (enExample)
CN (2) CN104114179A (enExample)
AU (3) AU2012354056B2 (enExample)
CA (2) CA3056570C (enExample)
DK (1) DK2790710T3 (enExample)
ES (1) ES2831699T3 (enExample)
IL (2) IL233107B (enExample)
WO (1) WO2013088440A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150374747A1 (en) * 2013-02-11 2015-12-31 Amorphical Ltd. Amorphous calcium carbonate for accelerated bone growth
EP3174828A4 (en) * 2014-07-31 2018-01-17 Amorphical Ltd. Non-aqueous liquid and semi-solid formulations of amorphous calcium carbonate
RU2748976C2 (ru) * 2015-06-04 2021-06-02 Аморфикал Лтд. Композиции аморфного карбоната кальция для ингаляции, подъязычного или трансбуккального введения
US12121538B2 (en) 2015-06-04 2024-10-22 Amorphical Ltd. Compositions of amorphous calcium carbonate for inhalation, sublingual or buccal administration
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
JP6873389B2 (ja) 2016-01-18 2021-05-19 アモーフィカル リミテッド． 神経学的、筋肉、および不妊の疾患または症状の治療のための安定化無定形炭酸カルシウム
CN108778295A (zh) 2016-01-18 2018-11-09 艾玛菲克有限公司 作为细胞培养基补充剂的稳定的无定形碳酸钙
US20230365935A1 (en) * 2016-01-18 2023-11-16 Amorphical Ltd. Stabilized amorphous calcium carbonate as a supplement for cell culture media
JP6872680B2 (ja) * 2016-03-22 2021-05-19 国立大学法人 宮崎大学 カルシウム吸収促進剤
US11052108B2 (en) 2016-10-25 2021-07-06 Amorphical Ltd. Amorphous calcium carbonate for treating a leukemia
CN110123836A (zh) * 2019-05-20 2019-08-16 昆明朗盛生物科技有限公司 钙锌维生素d泛酸片的应用
CA3144221A1 (en) 2019-07-23 2021-01-28 Amorphical Ltd Amorphous calcium carbonate for improving athletic performance
EP4117685A4 (en) * 2020-03-11 2024-03-20 Amorphical Ltd. AMORPHOUS CALCIUM CARBONATE FOR THE TREATMENT OF ACIDOSIS
WO2021226064A1 (en) * 2020-05-04 2021-11-11 University Of Louisville Research Foundation, Inc. Artificial intelligence-based systems and methods for dosing of pharmacologic agents
WO2022058337A1 (en) * 2020-09-15 2022-03-24 Oncoinvent As Size controlled radiolabelled particles
JP7573310B2 (ja) * 2022-02-28 2024-10-25 一般社団法人 Unical ヒトによる経口摂取のためのカルシウム組成物
EP4615802A1 (en) * 2022-11-08 2025-09-17 Amorphical Ltd. Methods for preparing amorphous calcium carbonate by fixation of carbon dioxide

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115414A2 (en) * 2004-05-26 2005-12-08 Ben-Gurion University Of The Negev Research And Development Authority Orally-administrable compositions comprising stable amorphous calcium carbonate
WO2008041236A2 (en) * 2006-10-05 2008-04-10 Ben-Gurion University Of The Negev Research And Development Authority Composition comprising crustacean gastrolith components, calcium carbonate and its use
WO2009053967A1 (en) * 2007-10-22 2009-04-30 Amorphical Ltd. Stable amorphous calcium carbonate comprising phosphorylated amino acids, synthetic phosphorylated peptides, and gastrolith proteins

Family Cites Families (13)

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IL87452A (en) 1987-08-28 1992-07-15 Norwich Eaton Pharma Calcium citrate malate and calcium supplements containing it
CA1336328C (en) 1988-04-11 1995-07-18 Walter G. Leonard Method of increasing bone density in humans
AU1366697A (en) 1995-12-26 1997-07-28 Holomed Aps A method and system for generating an x-ray image
JPH10236957A (ja) 1997-02-24 1998-09-08 Bankaku Souhonpo:Kk 骨粗鬆症の改善剤
SE9702401D0 (sv) * 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
JP2003292453A (ja) 2002-04-02 2003-10-15 Asahi Kasei Corp 骨疾患治療用医薬複合剤
US7267832B2 (en) * 2004-02-18 2007-09-11 Kraft Foods Holdings, Inc. Amorphous water-soluble calcium citrate salts and method of making and using same
US20070041506A1 (en) 2005-08-22 2007-02-22 Michelle Bottino Digital sensor holder
GB0522045D0 (en) 2005-10-28 2005-12-07 Novartis Ag Pharmaceutical compositions
WO2009087553A1 (en) * 2008-01-02 2009-07-16 Aurobindo Pharma Limited Kits for administering bisphosphonates
CN101314031A (zh) 2008-07-14 2008-12-03 王冰 一种改善骨营养的制剂
JP2012505728A (ja) * 2008-10-17 2012-03-08 フレゼニウス メディカル ケア ホールディングス インコーポレイテッド 透析患者のためのリン結合剤投与量の決定方法
CN102085356B (zh) 2010-12-28 2013-02-27 北京同仁堂健康药业股份有限公司 一种用于增加骨密度的组合物及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115414A2 (en) * 2004-05-26 2005-12-08 Ben-Gurion University Of The Negev Research And Development Authority Orally-administrable compositions comprising stable amorphous calcium carbonate
WO2008041236A2 (en) * 2006-10-05 2008-04-10 Ben-Gurion University Of The Negev Research And Development Authority Composition comprising crustacean gastrolith components, calcium carbonate and its use
WO2009053967A1 (en) * 2007-10-22 2009-04-30 Amorphical Ltd. Stable amorphous calcium carbonate comprising phosphorylated amino acids, synthetic phosphorylated peptides, and gastrolith proteins

Also Published As

Publication number Publication date
IL274755B (en) 2021-04-29
JP2015500333A (ja) 2015-01-05
CN109568338A (zh) 2019-04-05
US20190022133A1 (en) 2019-01-24
US20150056306A1 (en) 2015-02-26
AU2017279824A1 (en) 2018-01-25
ES2831699T3 (es) 2021-06-09
AU2012354056A8 (en) 2017-10-12
DK2790710T3 (da) 2020-11-30
EP2790710A1 (en) 2014-10-22
CN104114179A (zh) 2014-10-22
CA3056570A1 (en) 2013-06-20
AU2020200704A1 (en) 2020-02-20
US10688124B2 (en) 2020-06-23
WO2013088440A1 (en) 2013-06-20
CA3056570C (en) 2022-04-19
IL233107A0 (en) 2014-07-31
IL274755A (en) 2020-07-30
CA2859122C (en) 2019-11-05
WO2013088440A8 (en) 2013-08-01
EP2790710B1 (en) 2020-08-26
JP2019214631A (ja) 2019-12-19
JP2018138591A (ja) 2018-09-06
US10064890B2 (en) 2018-09-04
EP2790710A4 (en) 2015-11-11
IL233107B (en) 2020-06-30
AU2012354056A1 (en) 2014-07-10
CA2859122A1 (en) 2013-06-20

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Free format text: IN VOL 28 , NO 27 , PAGE(S) 3636 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME AMORPHICAL LTD., APPLICATION NO. 2012354056, UNDER INID (72) CORRECT THE CO-INVENTOR TO DANIELY, MICHAL

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