ES2827953T3 - Medicamento externo para neurofibroma plexiforme difuso - Google Patents

Medicamento externo para neurofibroma plexiforme difuso Download PDF

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Publication number
ES2827953T3
ES2827953T3 ES16768422T ES16768422T ES2827953T3 ES 2827953 T3 ES2827953 T3 ES 2827953T3 ES 16768422 T ES16768422 T ES 16768422T ES 16768422 T ES16768422 T ES 16768422T ES 2827953 T3 ES2827953 T3 ES 2827953T3
Authority
ES
Spain
Prior art keywords
weight
sirolimus
external
concentration
external drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16768422T
Other languages
English (en)
Spanish (es)
Inventor
Mari Kaneda
Ichiro Katayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Osaka NUC
Original Assignee
Osaka University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University NUC filed Critical Osaka University NUC
Application granted granted Critical
Publication of ES2827953T3 publication Critical patent/ES2827953T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES16768422T 2015-03-23 2016-03-09 Medicamento externo para neurofibroma plexiforme difuso Active ES2827953T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015059041A JP6541124B2 (ja) 2015-03-23 2015-03-23 びまん性神経線維腫用の外用薬
PCT/JP2016/057330 WO2016152519A1 (ja) 2015-03-23 2016-03-09 びまん性神経線維腫用の外用薬

Publications (1)

Publication Number Publication Date
ES2827953T3 true ES2827953T3 (es) 2021-05-25

Family

ID=56978382

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16768422T Active ES2827953T3 (es) 2015-03-23 2016-03-09 Medicamento externo para neurofibroma plexiforme difuso

Country Status (7)

Country Link
US (1) US10117857B2 (OSRAM)
EP (1) EP3275441B1 (OSRAM)
JP (1) JP6541124B2 (OSRAM)
CN (1) CN107708694A (OSRAM)
ES (1) ES2827953T3 (OSRAM)
HK (1) HK1250917A1 (OSRAM)
WO (1) WO2016152519A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3932487A4 (en) * 2019-02-27 2022-11-02 Osaka University EXTERNAL PREPARATION FOR THE TREATMENT OF VASCULAR ANOMALIES
WO2021075328A1 (ja) * 2019-10-16 2021-04-22 国立大学法人大阪大学 てんかん治療用又は自閉症スペクトラム障害治療用外用剤
CN113332228B (zh) * 2021-04-29 2023-03-31 杭州中美华东制药有限公司 一种西罗莫司凝胶制剂
DE102023119976A1 (de) * 2023-07-27 2025-01-30 Nobelpharma Co., Ltd. Rapamycin-haltige pharmazeutische zusammensetzung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060160837A1 (en) * 2004-12-29 2006-07-20 The Brigham And Women's Hospital, Inc. Rapamycin compounds in the treatment of neurofibromatosis type 1
CN101155577B (zh) * 2005-02-02 2015-04-22 耐克斯詹尼克斯医药有限公司 神经纤维瘤的局部治疗
CA2637255C (en) * 2006-02-02 2018-06-12 Novartis Ag 40-o-(2-hydroxyethyl)-rapamycin for treating tuberous sclerosis disorders
WO2009023877A2 (en) * 2007-08-16 2009-02-19 Macusight, Inc. Formulations for treatment of ocular diseases or conditions
US20130317053A1 (en) 2011-01-31 2013-11-28 Osaka University Externally-used drug for treating skin disorder and method for producing same

Also Published As

Publication number Publication date
WO2016152519A1 (ja) 2016-09-29
JP6541124B2 (ja) 2019-07-10
HK1250917A1 (zh) 2019-01-18
US10117857B2 (en) 2018-11-06
US20180110759A1 (en) 2018-04-26
EP3275441A4 (en) 2019-01-16
JP2016175884A (ja) 2016-10-06
EP3275441B1 (en) 2020-08-12
EP3275441A1 (en) 2018-01-31
CN107708694A (zh) 2018-02-16

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