ES2774321T3 - Trastornos neurodegenerativos y métodos de tratamiento y diagnóstico de los mismos - Google Patents
Trastornos neurodegenerativos y métodos de tratamiento y diagnóstico de los mismos Download PDFInfo
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- ES2774321T3 ES2774321T3 ES14861265T ES14861265T ES2774321T3 ES 2774321 T3 ES2774321 T3 ES 2774321T3 ES 14861265 T ES14861265 T ES 14861265T ES 14861265 T ES14861265 T ES 14861265T ES 2774321 T3 ES2774321 T3 ES 2774321T3
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Classifications
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A—HUMAN NECESSITIES
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- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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| US201361904365P | 2013-11-14 | 2013-11-14 | |
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| ES2774321T3 true ES2774321T3 (es) | 2020-07-20 |
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| EP1929995A1 (en) | 2006-12-04 | 2008-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anaplerotic therapy of Huntington disease and other polyglutamine diseases |
| CN104955450A (zh) | 2012-12-13 | 2015-09-30 | 达拉斯贝勒研究院 | 用于治疗葡萄糖转运体1缺乏症的三庚酸甘油酯 |
| EP3689343A1 (en) | 2013-11-14 | 2020-08-05 | The University of Queensland | Neurodegenerative disorders and methods of treatment and diagnosis thereof using anaplerotic agents |
| US12109182B2 (en) | 2016-04-19 | 2024-10-08 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate and related compounds in humans |
| WO2017208217A2 (en) * | 2016-06-01 | 2017-12-07 | Aspi Ip Holder Llc | C5 ketone compositions, and related methods, for therapeutic and performance supplementation |
| TWI749016B (zh) * | 2016-06-08 | 2021-12-11 | 董宇紅 | 具有奇數碳的脂類化合物及其作為醫藥組合物或者營養補充劑的用途 |
| BR112020004023A2 (pt) * | 2017-09-12 | 2020-09-08 | Sunregen Healthcare Ag | uso de um composto e composição farmacêutica ou suplemento nutricional |
| US12090129B2 (en) | 2017-11-22 | 2024-09-17 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US11944598B2 (en) | 2017-12-19 | 2024-04-02 | Axcess Global Sciences, Llc | Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer |
| US12329734B2 (en) | 2017-12-19 | 2025-06-17 | Axcess Global Sciences, Llc | Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow |
| US12472200B2 (en) | 2019-05-15 | 2025-11-18 | Axcess Global Sciences, Llc | Autobiotic compositions and method for promoting healthy gut microbiome |
| US11969430B1 (en) | 2023-03-10 | 2024-04-30 | Axcess Global Sciences, Llc | Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance |
| US12167993B2 (en) | 2019-06-21 | 2024-12-17 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
| US12186297B2 (en) | 2020-08-26 | 2025-01-07 | Axcess Global Sciences, Llc | Compositions and methods for increasing lean-to-fat mass ratio |
| CN113917034A (zh) * | 2021-10-19 | 2022-01-11 | 北京豪思生物科技有限公司 | 用于评估阿尔茨海默症的生物标记组合及其应用和试剂盒 |
| EP4651868A2 (en) * | 2023-01-20 | 2025-11-26 | Keto Innovations, LLC | C5 ketones for inducing weight loss and improving cognitive function |
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| DE3032300A1 (de) | 1980-08-27 | 1982-04-01 | Alfred Ing. Wien Lohninger | Mittel zur parenteralen ernaehrung |
| GB2104079B (en) | 1981-08-14 | 1985-08-21 | London Polytech | New aminoacid isomers, their production and their medicinal use |
| US4753963A (en) | 1985-09-26 | 1988-06-28 | The Procter & Gamble Company | Nutritional fat suitable for enteral and parenteral products |
| JP3486778B2 (ja) | 1993-04-02 | 2004-01-13 | 三菱ウェルファーマ株式会社 | アルツハイマー病予防治療剤 |
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| WO2001032168A1 (en) | 1999-11-03 | 2001-05-10 | Juvenon, Inc. | Method of treating benign forgetfulness |
| US20020006959A1 (en) | 2000-05-01 | 2002-01-17 | Henderson Samuel T. | Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| WO2004077938A2 (en) | 2003-03-06 | 2004-09-16 | Accera Inc. | Novel chemical entities and methods for their use in treatment of metabolic disorders |
| US8399515B2 (en) | 2003-05-20 | 2013-03-19 | Baylor Research Institute | Five and fifteen carbon fatty acids for treating metabolic disorders and as nutritional supplements |
| CA2573054C (en) | 2004-07-02 | 2012-10-09 | Baylor Research Institute | Glycogen or polysaccharide storage disease treatment method |
| WO2006037069A1 (en) | 2004-09-28 | 2006-04-06 | Allergan, Inc. | Compositions comprising nb-dnj, ne-dnj or d-glucaro-delta-lactam and their uses for the treatment of pain and other neurological conditions |
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| AU2008282130B2 (en) | 2007-07-31 | 2014-08-21 | Cerecin Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
| WO2009124250A1 (en) * | 2008-04-03 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Compositions and methods for detecting tricarboxylic acid (tca) metabolic flux |
| EP2519234B1 (en) | 2009-12-30 | 2017-06-28 | Baylor Research Institute | Anaplerotic therapy for alzheimer's disease |
| US20110301238A1 (en) * | 2010-06-02 | 2011-12-08 | Borges Karin | Seizure related disorders and therapeutic methods thereof |
| WO2011159634A1 (en) | 2010-06-14 | 2011-12-22 | Baylor Research Institute | Triheptanoin diet for adult polyglucosan body disease (apbd) treatment |
| US9872850B2 (en) * | 2010-12-23 | 2018-01-23 | Amazentis Sa | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders |
| EP2599482A1 (en) * | 2011-11-30 | 2013-06-05 | Lunamed AG | Low dose therapeutic use of glyceryl tri-(4-phenylbutyrate) |
| CN104955450A (zh) | 2012-12-13 | 2015-09-30 | 达拉斯贝勒研究院 | 用于治疗葡萄糖转运体1缺乏症的三庚酸甘油酯 |
| EP3689343A1 (en) | 2013-11-14 | 2020-08-05 | The University of Queensland | Neurodegenerative disorders and methods of treatment and diagnosis thereof using anaplerotic agents |
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| AU2014348457A1 (en) | 2016-05-26 |
| US9833430B2 (en) | 2017-12-05 |
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| EP3068492B1 (en) | 2020-01-08 |
| JP6588903B2 (ja) | 2019-10-09 |
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| US20160263071A1 (en) | 2016-09-15 |
| CA2929601A1 (en) | 2015-05-21 |
| US20180207121A1 (en) | 2018-07-26 |
| EP3689343A1 (en) | 2020-08-05 |
| WO2015073803A1 (en) | 2015-05-21 |
| AU2014348457B2 (en) | 2019-04-18 |
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