ES2770585T3 - Métodos y composiciones para el tratamiento de la diverticulosis - Google Patents
Métodos y composiciones para el tratamiento de la diverticulosis Download PDFInfo
- Publication number
- ES2770585T3 ES2770585T3 ES12860587T ES12860587T ES2770585T3 ES 2770585 T3 ES2770585 T3 ES 2770585T3 ES 12860587 T ES12860587 T ES 12860587T ES 12860587 T ES12860587 T ES 12860587T ES 2770585 T3 ES2770585 T3 ES 2770585T3
- Authority
- ES
- Spain
- Prior art keywords
- glutamine
- diverticulosis
- salt
- use according
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010013554 Diverticulum Diseases 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 10
- 239000000203 mixture Substances 0.000 title claims description 31
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims abstract description 36
- 229930182816 L-glutamine Natural products 0.000 claims abstract description 35
- 150000003839 salts Chemical class 0.000 claims abstract description 16
- 230000037396 body weight Effects 0.000 claims abstract description 10
- 150000008540 L-glutamines Chemical class 0.000 claims abstract description 5
- 239000000835 fiber Substances 0.000 claims description 18
- 239000013589 supplement Substances 0.000 claims description 8
- 206010013530 Diverticula Diseases 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 235000003421 Plantago ovata Nutrition 0.000 claims description 3
- 239000009223 Psyllium Substances 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 229920000609 methyl cellulose Polymers 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 229940070687 psyllium Drugs 0.000 claims description 3
- 229920001353 Dextrin Polymers 0.000 claims description 2
- 239000007910 chewable tablet Substances 0.000 claims description 2
- 229940068682 chewable tablet Drugs 0.000 claims description 2
- 239000001923 methylcellulose Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 229940075430 wheat dextrin Drugs 0.000 claims description 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims 1
- 241001499733 Plantago asiatica Species 0.000 claims 1
- 239000007900 aqueous suspension Substances 0.000 claims 1
- 229960002900 methylcellulose Drugs 0.000 claims 1
- -1 olefin salt Chemical class 0.000 description 12
- 210000001072 colon Anatomy 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
- 238000002052 colonoscopy Methods 0.000 description 3
- 244000134552 Plantago ovata Species 0.000 description 2
- 229940125782 compound 2 Drugs 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 208000007784 diverticulitis Diseases 0.000 description 2
- 239000003623 enhancer Substances 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 235000021071 low fiber diet Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 239000004381 Choline salt Substances 0.000 description 1
- 244000303965 Cyamopsis psoralioides Species 0.000 description 1
- 208000012258 Diverticular disease Diseases 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 206010017943 Gastrointestinal conditions Diseases 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 159000000021 acetate salts Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
- 229940029830 benefiber Drugs 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229960002023 chloroprocaine Drugs 0.000 description 1
- 235000019417 choline salt Nutrition 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 229940081970 citrucel Drugs 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- YKGMKSIHIVVYKY-UHFFFAOYSA-N dabrafenib mesylate Chemical compound CS(O)(=O)=O.S1C(C(C)(C)C)=NC(C=2C(=C(NS(=O)(=O)C=3C(=CC=CC=3F)F)C=CC=2)F)=C1C1=CC=NC(N)=N1 YKGMKSIHIVVYKY-UHFFFAOYSA-N 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000021004 dietary regimen Nutrition 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 235000009569 green tea Nutrition 0.000 description 1
- 235000021192 high fiber diet Nutrition 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 229960003194 meglumine Drugs 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229940042003 metamucil Drugs 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N monoethanolamine hydrochloride Natural products NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 150000003891 oxalate salts Chemical class 0.000 description 1
- AICOOMRHRUFYCM-ZRRPKQBOSA-N oxazine, 1 Chemical compound C([C@@H]1[C@H](C(C[C@]2(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@]21C)=O)CC1=CC2)C[C@H]1[C@@]1(C)[C@H]2N=C(C(C)C)OC1 AICOOMRHRUFYCM-ZRRPKQBOSA-N 0.000 description 1
- 229940124641 pain reliever Drugs 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000019371 penicillin G benzathine Nutrition 0.000 description 1
- 229940023488 pill Drugs 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 230000036186 satiety Effects 0.000 description 1
- 235000019627 satiety Nutrition 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229960000281 trometamol Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A23L33/24—Cellulose or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/721—Dextrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161630831P | 2011-12-19 | 2011-12-19 | |
| PCT/US2012/000576 WO2013095681A1 (en) | 2011-12-19 | 2012-12-14 | Methods and compositions for the treatment of diverticulosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2770585T3 true ES2770585T3 (es) | 2020-07-02 |
Family
ID=48669319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12860587T Active ES2770585T3 (es) | 2011-12-19 | 2012-12-14 | Métodos y composiciones para el tratamiento de la diverticulosis |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9616041B2 (enExample) |
| EP (2) | EP3603631B1 (enExample) |
| JP (1) | JP6060176B2 (enExample) |
| KR (4) | KR20180039187A (enExample) |
| CN (1) | CN104114165B (enExample) |
| AU (1) | AU2012355956B2 (enExample) |
| BR (1) | BR112014014765A8 (enExample) |
| DK (1) | DK2793875T3 (enExample) |
| ES (1) | ES2770585T3 (enExample) |
| IN (1) | IN2014KN01255A (enExample) |
| MX (1) | MX351688B (enExample) |
| RU (2) | RU2662917C2 (enExample) |
| WO (1) | WO2013095681A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3603631B1 (en) * | 2011-12-19 | 2023-11-29 | Emmaus Medical, Inc. | Methods and compositions for the treatment of diverticulosis |
| CU20200106A7 (es) | 2018-06-20 | 2021-08-06 | Axcella Health Inc | Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias |
| EP3790545A4 (en) * | 2019-07-17 | 2021-07-28 | Emmaus Medical, Inc. | METHODS AND COMPOSITIONS FOR TREATMENT OF SICKLE CLEANEMIA AND THALASSEMIA |
| US20230053227A1 (en) * | 2021-07-27 | 2023-02-16 | G&S Laboratories, Inc. | Dietary fiber compositions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0738146B1 (en) * | 1994-01-11 | 2003-05-02 | N.V. Nutricia | Method of treating disorders of the animal or human body by administering amino acids |
| JP2000060487A (ja) * | 1998-08-27 | 2000-02-29 | Kao Corp | 便秘改善剤 |
| US7030092B1 (en) | 2001-08-24 | 2006-04-18 | Small Giant L.L.C. | Ultra-high fiber supplement and method of reducing weight cardiovascular risks and ingested toxins. |
| US20040005304A1 (en) * | 2002-07-08 | 2004-01-08 | Mak Wood, Inc. | Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions |
| US7988989B2 (en) * | 2003-05-09 | 2011-08-02 | Freedom Health, Llc | Nutritional product for enhancing growth and/or strengthening the immune system of equine foals |
| US20050058671A1 (en) * | 2003-05-09 | 2005-03-17 | Bedding Peter M.J. | Dietary supplement and method for treating digestive system-related disorders |
| US8512789B2 (en) * | 2005-11-23 | 2013-08-20 | The Coca-Cola Company | High-potency sweetener composition with dietary fiber and compositions sweetened therewith |
| US20080003265A1 (en) | 2006-06-28 | 2008-01-03 | John Francis Casey | Protein and fiber containing dietary supplement |
| PL2561766T3 (pl) * | 2006-11-07 | 2018-06-29 | The Procter And Gamble Company | Kompozycje zawierające błonnik oraz sposoby ich wytwarzania i stosowania |
| RU2454730C1 (ru) * | 2011-03-15 | 2012-06-27 | Александр Михайлович Пузиков | Способ лечения дивертикулеза в эксперименте |
| EP3603631B1 (en) * | 2011-12-19 | 2023-11-29 | Emmaus Medical, Inc. | Methods and compositions for the treatment of diverticulosis |
-
2012
- 2012-12-14 EP EP19199336.9A patent/EP3603631B1/en active Active
- 2012-12-14 RU RU2014123433A patent/RU2662917C2/ru active
- 2012-12-14 KR KR1020187009799A patent/KR20180039187A/ko not_active Ceased
- 2012-12-14 RU RU2018126834A patent/RU2733396C2/ru active
- 2012-12-14 MX MX2014007382A patent/MX351688B/es active IP Right Grant
- 2012-12-14 CN CN201280062802.4A patent/CN104114165B/zh active Active
- 2012-12-14 US US13/694,592 patent/US9616041B2/en active Active
- 2012-12-14 WO PCT/US2012/000576 patent/WO2013095681A1/en not_active Ceased
- 2012-12-14 ES ES12860587T patent/ES2770585T3/es active Active
- 2012-12-14 EP EP12860587.0A patent/EP2793875B1/en active Active
- 2012-12-14 KR KR1020177008405A patent/KR101848722B1/ko active Active
- 2012-12-14 AU AU2012355956A patent/AU2012355956B2/en active Active
- 2012-12-14 BR BR112014014765A patent/BR112014014765A8/pt not_active Application Discontinuation
- 2012-12-14 KR KR1020177020002A patent/KR20170087531A/ko not_active Ceased
- 2012-12-14 KR KR1020147016785A patent/KR20140103281A/ko not_active Ceased
- 2012-12-14 DK DK12860587.0T patent/DK2793875T3/da active
- 2012-12-14 JP JP2014547181A patent/JP6060176B2/ja active Active
-
2014
- 2014-06-10 IN IN1255/KOLNP/2014A patent/IN2014KN01255A/en unknown
-
2017
- 2017-02-10 US US15/530,630 patent/US10258586B2/en active Active
-
2019
- 2019-02-11 US US16/501,039 patent/US11304918B2/en active Active
-
2022
- 2022-03-09 US US17/803,158 patent/US20220202758A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7629432B2 (ja) | グルタチオンレベルを改善するためのｎ－アセチルシステイン及びグリシンの補給の効果 | |
| US20200140371A1 (en) | S-enantiomers of beta-hydroxybutyrate and butanediol and methods for using same | |
| US20220202758A1 (en) | Methods and compositions for the treatment of diverticulosis | |
| ES2864136T3 (es) | Composición farmacéutica para la prevención de obesidad inducida por la dieta | |
| ES3041002T3 (en) | Methods for treating hyperphenylalaninemia | |
| ES2385935T3 (es) | Reducción de mareos, un efecto secundario asociado con la terapia de pirfenidona. | |
| CN108495624A (zh) | 包含β-羟基-β甲基丁酸酯的药物或营养组合 | |
| ES2814951T3 (es) | Compuestos y sus efectos sobre el control del apetito y la sensibilidad a la insulina | |
| US20110076339A1 (en) | Colon Cleansing Method and Kit | |
| Kamm | chronic active disease and maintaining remission in Crohn's disease | |
| JPWO2006098524A1 (ja) | ストレスによる腸疾患の予防・治療剤 | |
| JP2021536494A (ja) | マグネシウム含有製剤及びその使用 | |
| RU2613765C1 (ru) | Способ лечения спиноцеребеллярной атаксии | |
| AU2016374453A1 (en) | Compositions comprising 3'-O-glucuronide epicatechin and methods of making and using such compositions | |
| WO2013076339A1 (es) | Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia | |
| CN102655862A (zh) | 用于降低血液中的尿酸值的组合物 | |
| Kozel et al. | Chronic Feeding Intolerance: Management in Geriatric Palliative Care | |
| Liza | Impact of Different Supplement Drugs on the Dissolution Profile of Zantac and Xantid | |
| Meglio | Celebrating LGMD Awareness Day: Advances and Future Directions | |
| JPWO2016199798A1 (ja) | 運動誘発性の消化管障害の改善剤 | |
| HK1108563B (zh) | 富含亮氨酸的营养组合物 | |
| HK1108563A1 (en) | Leucine-enriched nutritional compositions |