ES2768651T3 - Composición farmacéutica sólida - Google Patents

Composición farmacéutica sólida Download PDF

Info

Publication number
ES2768651T3
ES2768651T3 ES14787908T ES14787908T ES2768651T3 ES 2768651 T3 ES2768651 T3 ES 2768651T3 ES 14787908 T ES14787908 T ES 14787908T ES 14787908 T ES14787908 T ES 14787908T ES 2768651 T3 ES2768651 T3 ES 2768651T3
Authority
ES
Spain
Prior art keywords
tio
mpos
ico
tic
ica
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14787908T
Other languages
English (en)
Spanish (es)
Inventor
Hiroshi Uchida
Masataka Hanada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2768651T3 publication Critical patent/ES2768651T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20Mixing gases with liquids
    • B01F23/23Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/235Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids for making foam

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES14787908T 2013-04-25 2014-04-24 Composición farmacéutica sólida Active ES2768651T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013092171 2013-04-25
PCT/JP2014/002308 WO2014174846A1 (ja) 2013-04-25 2014-04-24 固形医薬組成物

Publications (1)

Publication Number Publication Date
ES2768651T3 true ES2768651T3 (es) 2020-06-23

Family

ID=51791434

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14787908T Active ES2768651T3 (es) 2013-04-25 2014-04-24 Composición farmacéutica sólida

Country Status (7)

Country Link
US (1) US9603804B2 (enExample)
EP (1) EP2990038B1 (enExample)
JP (2) JP5651812B1 (enExample)
CN (1) CN105338982B (enExample)
CA (1) CA2910112C (enExample)
ES (1) ES2768651T3 (enExample)
WO (1) WO2014174846A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014174847A1 (ja) 2013-04-25 2014-10-30 杏林製薬株式会社 固形医薬組成物
WO2016063542A1 (ja) * 2014-10-23 2016-04-28 杏林製薬株式会社 固形医薬組成物
US20170246160A1 (en) * 2014-10-23 2017-08-31 Kyorin Pharmaceutical Co., Ltd. Solid pharmaceutical composition
WO2016195014A1 (ja) * 2015-06-02 2016-12-08 杏林製薬株式会社 水性液剤
JP6031217B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
US10406149B2 (en) 2015-06-02 2019-09-10 Kyorin Pharmaceutical Co., Ltd. Aqueous liquid formulation
JP6675396B2 (ja) * 2015-06-02 2020-04-01 杏林製薬株式会社 水性液剤
JP6031216B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
JP2021519334A (ja) 2018-03-26 2021-08-10 クリア クリーク バイオ, インコーポレイテッド ジヒドロオロト酸デヒドロゲナーゼを阻害するための組成物および方法
US20210300873A1 (en) 2020-03-20 2021-09-30 Clear Creek Bio, Inc. Stable polymorphic compositions of brequinar sodium and methods of use and manufacture thereof
JP2023518419A (ja) * 2020-03-20 2023-05-01 クリア クリーク バイオ, インコーポレイテッド ブレキナルナトリウムの安定した多形性組成物ならびにその使用および製造方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524001D0 (en) 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
ZA87279B (en) 1986-01-17 1987-09-30 Chugai Pharmaceutical Co Ltd Method for production of stable nicorandil preparation
KR940000232B1 (ko) 1986-01-17 1994-01-12 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 제제의 안정화 방법
JP2512302B2 (ja) 1986-03-19 1996-07-03 中外製薬株式会社 ニコランジル安定化製剤の製造方法
KR910700043A (ko) 1988-12-28 1991-03-13 우에하라 아끼라 타정시에 있어서 응력분산 방법
JP2682353B2 (ja) 1991-11-20 1997-11-26 武田薬品工業株式会社 経口用医薬組成物およびその製造法
TW284688B (enExample) 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
JP2006111639A (ja) 1993-10-21 2006-04-27 Takeda Chem Ind Ltd 医薬用錠剤
JPH08175996A (ja) 1994-12-22 1996-07-09 Taiyo Yakuhin Kogyo Kk ニコランジル安定化固形製剤の製法
JP3119801B2 (ja) 1995-09-28 2000-12-25 武田薬品工業株式会社 ビタミン含有組成物の安定化方法
JPH10245335A (ja) 1997-02-28 1998-09-14 Dainippon Pharmaceut Co Ltd 圧力に不安定な薬物の打錠方法及びそれに用いられる湿潤顆粒
ATE232728T1 (de) 1998-03-03 2003-03-15 Dae Woong Pharma Feuchtigkeitsstabile cefuroxim axetil enthaltende pharmazeutische zusammenstellungen
AT413647B (de) 1998-11-26 2006-04-15 Sandoz Ag Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten
DE10048510A1 (de) 2000-09-29 2002-05-16 Fresenius Kabi De Gmbh Lagerstabile Infusionslösung des Ciprofloxacins mit verringertem Säuregehalt
ES2248521T3 (es) 2001-02-27 2006-03-16 Ranbaxy Laboratories, Ltd. Composicion farmaceutica oral de cefpodoxima proxetilo.
US7219132B2 (en) 2001-03-30 2007-05-15 Space Systems/Loral Dynamic resource allocation architecture for differentiated services over broadband communication networks
BR0308643A (pt) 2002-03-18 2005-02-09 Kyorin Seiyaku Kk Composto do derivado do ácido piridobenzoxazina carboxìlico e agente antibacteriano contendo o mesmo
ATE382338T1 (de) 2003-03-19 2008-01-15 Jordanian Pharmaceutical Mfg Nicht-hygroskopische pharmazeutische zusammensetzungen die nicht hydratisierte quinolon-carbonsäure enthalten
JP4639149B2 (ja) 2003-09-10 2011-02-23 杏林製薬株式会社 7−(4−置換−3−シクロプロピルアミノメチル−1−ピロリジニル)キノロンカルボン酸誘導体
EP1764102A4 (en) 2004-07-02 2010-08-25 Daiichi Seiyaku Co MEDICINAL COMPOSITION CONTAINING QUINOLONE
ES2322175T3 (es) 2004-09-17 2009-06-17 EISAI R&D MANAGEMENT CO., LTD. Composicion medicinal con estabilidad mejorada y gelificacion reducida.
EP1825866A4 (en) 2004-12-03 2008-03-12 Takeda Pharmaceutical SOLID PREPARATION
AR052559A1 (es) 2005-01-21 2007-03-21 Astex Therapeutics Ltd Derivados de pirazol para inhibir cdk's y gsk's
EP1843754B1 (en) 2005-01-26 2011-08-03 LEK Pharmaceuticals d.d. New pharmaceutical composition containing candesartan cilexetil as lipophilic crystalline substance
JP2006298811A (ja) 2005-04-20 2006-11-02 Taiyo Yakuhin Kogyo Kk ゲル化抑制製剤の設計
SA112330992B1 (ar) * 2011-11-10 2015-09-13 كيورين فارماسوتيكال كو.، ليمتد صورة متبلرة من 7-{(s4، s3)-3-[(سيكلو بروبيل أمينو) ميثيل]-4-فلورو بيروليدين-1-يل}-6-فلورو-1-(2-فلورو إيثيل)- 8-ميثوكسي-4-أوكسو-1، 4-داي هيدرو كينولين-3- حمض كربوكسيلي
JP6062422B2 (ja) * 2012-03-29 2017-01-18 杏林製薬株式会社 カプセル製剤
JP6050322B2 (ja) * 2012-03-29 2016-12-21 杏林製薬株式会社 カプセル製剤
WO2014174847A1 (ja) 2013-04-25 2014-10-30 杏林製薬株式会社 固形医薬組成物

Also Published As

Publication number Publication date
JP6391436B2 (ja) 2018-09-19
WO2014174846A1 (ja) 2014-10-30
EP2990038A4 (en) 2016-11-16
EP2990038B1 (en) 2019-11-20
CN105338982A (zh) 2016-02-17
US9603804B2 (en) 2017-03-28
CA2910112A1 (en) 2014-10-30
JPWO2014174846A1 (ja) 2017-02-23
CN105338982B (zh) 2017-10-10
JP2015078201A (ja) 2015-04-23
EP2990038A1 (en) 2016-03-02
CA2910112C (en) 2021-02-16
US20160067185A1 (en) 2016-03-10
JP5651812B1 (ja) 2015-01-14

Similar Documents

Publication Publication Date Title
ES2768651T3 (es) Composición farmacéutica sólida
US9329191B2 (en) Reaction-based fluorescent probe for selective detection of carbon monoxide using metal-mediated carbonylation
US9815764B2 (en) Homochiral metal-organic framework with enantiopure pillar[5]arene active domains
Momme et al. Platinum-group elements in the Icelandic rift system: melting processes and mantle sources beneath Iceland
Yang et al. Diastereoselective synthesis of O symmetric heterometallic cubic cages
Chiocchio et al. Monoamines in the carotid body cells of the cat
CN104072390B (zh) 一种艾司西酞普兰化合物及其制备方法
Evans et al. Complete stereocontrol in the synthesis of macrocyclic lanthanide complexes: direct formation of enantiopure systems for circularly polarised luminescence applications
Saliba et al. Stimulating effect of both 4’‐O‐methylnorbelladine feeding and temporary immersion conditions on galanthamine and lycorine production by Leucojum aestivum L. bulblets
Meijers et al. Climate stability in central Anatolia during the Messinian Salinity Crisis
Sundaresan et al. Alpha-and beta-adrenergic receptors in proximal tubules of rat kidney
JPS6054345A (ja) エナンチオマ−を薄層クロマトグラフイ−分離する方法
Abreu et al. Characterization of the variation in the imidazole alkaloid profile of Pilocarpus microphyllus in different seasons and parts of the plant by electrospray ionization mass spectrometry fingerprinting and identification of novel alkaloids by tandem mass spectrometry
Mallette et al. The isotopic fractionation of carbon, nitrogen, hydrogen, and oxygen during illicit production of cocaine base in South America
Németh et al. Synthesis and pKa determination of new enantiopure dimethyl‐substituted acridino‐crown ethers containing a carboxyl group: Useful candidates for enantiomeric recognition studies
CN107525877B (zh) 一种采用液相色谱法分离测定依匹哌唑及其杂质的方法
US10828324B2 (en) Production of water-soluble hydrolyzed clinoptilolite fragments
Bailar Jr et al. The Stereochemistry of Complex Inorganic Compounds. VII. 1 The Mechanism of the Walden Inversion in Some Reactions Leading to the Formation of the Carbonato-diethylenediamine Cobaltic Ion
AU720219B2 (en) New dosage form of hydroxocobalamin and its use in cyanide poisoning
Antoine Lanfranchi et al. Enantiomeric differentiation of atropine/hyoscyamine by 13C NMR spectroscopy and its application to Datura stramonium extract
Martin et al. Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality
Vyas et al. Reversed‐phase‐HPLC enantioseparation and control of enantiomeric purity of duloxetine using a new chiral reagent and recovery of enantiomers
Górecki et al. Circularly Polarized Luminescence From Spontaneous Symmetry Breaking in a Bimetallic Eu–Al Complex
Strauss THE PHYSIOLOGY OF POLLINATION INDUCED PHENOMENA IN THE ORCHIDACEAE.
CN102399169B (zh) 一种用于手性羧酸对映体分析和拆分的化合物及其制备方法