ES2749651T3 - Método basado en microARN para la detección temprana de cáncer de próstata en muestras de orina - Google Patents

Método basado en microARN para la detección temprana de cáncer de próstata en muestras de orina Download PDF

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ES2749651T3
ES2749651T3 ES16706303T ES16706303T ES2749651T3 ES 2749651 T3 ES2749651 T3 ES 2749651T3 ES 16706303 T ES16706303 T ES 16706303T ES 16706303 T ES16706303 T ES 16706303T ES 2749651 T3 ES2749651 T3 ES 2749651T3
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hsa
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Rønfeldt Thomsen
Jacob Fredsøe
Dalsgaard Sørensen
Lars Kongsbak
Peter Mouritzen
Torben Ørntoft
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Qiagen GmbH
Aarhus Universitet
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Aarhus Universitet
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES16706303T 2015-02-11 2016-02-05 Método basado en microARN para la detección temprana de cáncer de próstata en muestras de orina Active ES2749651T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201500079 2015-02-11
DKPA201500825 2015-12-21
PCT/DK2016/050032 WO2016127998A1 (en) 2015-02-11 2016-02-05 A microrna-based method for early detection of prostate cancer in urine samples

Publications (1)

Publication Number Publication Date
ES2749651T3 true ES2749651T3 (es) 2020-03-23

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ES16706303T Active ES2749651T3 (es) 2015-02-11 2016-02-05 Método basado en microARN para la detección temprana de cáncer de próstata en muestras de orina

Country Status (6)

Country Link
US (1) US10400288B2 (enExample)
EP (1) EP3256602B1 (enExample)
JP (1) JP2018504915A (enExample)
CA (1) CA2976577C (enExample)
ES (1) ES2749651T3 (enExample)
WO (1) WO2016127998A1 (enExample)

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WO2016134727A1 (en) 2015-02-27 2016-09-01 Exiqon A/S A microrna-based method for assessing the prognosis of a prostate cancer patient
WO2018049506A1 (en) * 2016-09-14 2018-03-22 Ontario Institute For Cancer Research (Oicr) Mirna prostate cancer marker
CN106834470A (zh) * 2017-02-17 2017-06-13 张灏 miRNA在制备癌症诊断试剂盒中的用途
WO2018159750A1 (ja) * 2017-03-02 2018-09-07 第一三共株式会社 オピオイド薬の治療有効性を予測するためのｍｉｃｒｏＲＮＡバイオマーカー
CN107488734B (zh) * 2017-10-10 2019-11-05 广州医科大学附属第二医院 miR-19a-3p在制备前列腺癌骨转移诊断试剂和治疗药物中的应用
CN107663541A (zh) * 2017-10-31 2018-02-06 温州医科大学 一种用于诊断原发性肝癌的特异性生物标志物及其筛选方法与应用
US20210147944A1 (en) * 2018-04-10 2021-05-20 Unity Health Toronto Methods for monitoring and treating prostate cancer
WO2019220759A1 (ja) * 2018-05-17 2019-11-21 Ｓｔｅｍｃｅｌｌ株式会社 がんの分析方法、がんの分析システム、プログラムおよびコンピュータ読み取り可能な記録媒体
CN108424962B (zh) * 2018-05-25 2021-08-03 中国人民解放军陆军军医大学 系膜增生性肾小球肾炎的miRNA检测标志物及其诊断试剂盒
CN109112109A (zh) * 2018-07-27 2019-01-01 浙江大学 一种骨髓间充质干细胞外泌体的改造方法
EP3699300A1 (en) * 2019-02-22 2020-08-26 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Seminal mirnas as non-invasive biomarkers for the diagnosis and/or prognosis of prostate cancer
JP2022524382A (ja) 2019-03-15 2022-05-02 エムアイアール サイエンティフィック，エルエルシー 前立腺がんを予測するための方法およびその使用
EP3719144A1 (en) * 2019-04-05 2020-10-07 Fundación para la Investigación Biomédica del Hospital Universitario de la Paz (FIBHULP) Mir-151a-3p as an universal endogenous control for exosome cargo normalization
JP2020195314A (ja) * 2019-05-31 2020-12-10 医薬資源研究所株式会社 疾患・体質の分析方法、疾患・体質の分析システム、プログラムおよびコンピュータ読み取り可能な記録媒体
JP7660898B2 (ja) * 2019-09-09 2025-04-14 Ｃｒａｉｆ株式会社 マイクロｒｎａを含む体液抽出物
CN111118165B (zh) * 2020-03-04 2023-04-07 朱伟 一种与前列腺癌辅助诊断相关的血清miRNA标志物及其应用
CN112094910B (zh) * 2020-09-25 2023-03-24 无锡市中医医院 一种用于前列腺癌患病风险评估的miRNA标志物
CN112795657A (zh) * 2021-03-22 2021-05-14 中国农业大学 miRNA在制备诊断或辅助诊断哺乳动物前列腺癌症产品中的应用
EP4317454A4 (en) * 2021-03-29 2025-02-19 Toray Industries, Inc. Method for detecting microrna in biological sample, composition of hydrochloride of neutral amino acid, and container
KR102550113B1 (ko) * 2021-05-28 2023-07-03 주식회사 시스바이오젠 전립선암 진단용 바이오마커 및 이의 용도
CN114045344B (zh) * 2021-12-09 2024-12-17 觅瑞（杭州）生物科技有限公司 前列腺癌诊断用尿液miRNA标志物、诊断试剂及试剂盒
ES2995178A1 (es) * 2023-07-31 2025-02-07 Servicio Andaluz De Salud Biomarcadores y método de diagnóstico de la diabetes monogénica en adultos jóvenes portadores de alelos HNF1A deletéreos

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CA2762986C (en) 2009-05-22 2018-03-06 Asuragen, Inc. Mirna biomarkers of prostate disease
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EP2341145A1 (en) * 2009-12-30 2011-07-06 febit holding GmbH miRNA fingerprint in the diagnosis of diseases
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EP2771487A1 (en) * 2011-10-27 2014-09-03 Asuragen, INC. Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors
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CA2834187A1 (en) * 2013-04-15 2014-10-15 Norgen Biotek Corporation Use of micrornas for screening and diagnosis of prostate cancer and benign prostatic hyperplasia
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KR102761162B1 (ko) * 2014-06-12 2025-02-03 국립연구개발법인 고쿠리츠간켄큐센터 전립선암 검출 키트 또는 디바이스 및 검출 방법
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Also Published As

Publication number Publication date
EP3256602B1 (en) 2019-09-04
US20180030542A1 (en) 2018-02-01
US10400288B2 (en) 2019-09-03
JP2018504915A (ja) 2018-02-22
EP3256602A1 (en) 2017-12-20
CA2976577A1 (en) 2016-08-18
WO2016127998A1 (en) 2016-08-18
CA2976577C (en) 2024-11-19

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