ES2719615T3 - Estructura de colector hidráulico compacto para fluidos sensibles a cizalladura - Google Patents
Estructura de colector hidráulico compacto para fluidos sensibles a cizalladura Download PDFInfo
- Publication number
- ES2719615T3 ES2719615T3 ES13765553T ES13765553T ES2719615T3 ES 2719615 T3 ES2719615 T3 ES 2719615T3 ES 13765553 T ES13765553 T ES 13765553T ES 13765553 T ES13765553 T ES 13765553T ES 2719615 T3 ES2719615 T3 ES 2719615T3
- Authority
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- Spain
- Prior art keywords
- channel
- channels
- fluid
- microfluidic device
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000012530 fluid Substances 0.000 title claims abstract description 84
- 239000008280 blood Substances 0.000 claims abstract description 66
- 210000004369 blood Anatomy 0.000 claims abstract description 66
- 239000012528 membrane Substances 0.000 claims abstract description 14
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 230000000295 complement effect Effects 0.000 claims abstract description 3
- 239000000758 substrate Substances 0.000 claims description 50
- 239000010410 layer Substances 0.000 description 42
- 239000000706 filtrate Substances 0.000 description 16
- 238000000034 method Methods 0.000 description 5
- 229920000089 Cyclic olefin copolymer Polymers 0.000 description 2
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- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
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- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
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- 230000001154 acute effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229920000229 biodegradable polyester Polymers 0.000 description 1
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- 230000017531 blood circulation Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 229910002090 carbon oxide Inorganic materials 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
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- 238000009792 diffusion process Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000002615 hemofiltration Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
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- 238000005459 micromachining Methods 0.000 description 1
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- 239000002071 nanotube Substances 0.000 description 1
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- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229920003213 poly(N-isopropyl acrylamide) Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- -1 polydimethylsiloxane Polymers 0.000 description 1
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- 239000000047 product Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229940116351 sebacate Drugs 0.000 description 1
- CXMXRPHRNRROMY-UHFFFAOYSA-L sebacate(2-) Chemical compound [O-]C(=O)CCCCCCCCC([O-])=O CXMXRPHRNRROMY-UHFFFAOYSA-L 0.000 description 1
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- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- XLOMVQKBTHCTTD-UHFFFAOYSA-N zinc oxide Inorganic materials [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1631—Constructional aspects thereof having non-tubular membranes, e.g. sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/005—Microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/082—Flat membrane modules comprising a stack of flat membranes
- B01D63/084—Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes
- B01D63/085—Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes specially adapted for two fluids in mass exchange flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/088—Microfluidic devices comprising semi-permeable flat membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D1/00—Pipe-line systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/08—Flow guidance means within the module or the apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/10—Specific supply elements
- B01D2313/105—Supply manifolds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2319/00—Membrane assemblies within one housing
- B01D2319/04—Elements in parallel
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/794—With means for separating solid material from the fluid
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Cardiology (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- External Artificial Organs (AREA)
- Water Supply & Treatment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/604,256 US9421315B2 (en) | 2012-09-05 | 2012-09-05 | Compact hydraulic manifold structure for shear sensitive fluids |
| PCT/US2013/057842 WO2014039441A1 (en) | 2012-09-05 | 2013-09-03 | Compact hydraulic manifold structure for shear sensitive fluids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2719615T3 true ES2719615T3 (es) | 2019-07-11 |
Family
ID=49223860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13765553T Active ES2719615T3 (es) | 2012-09-05 | 2013-09-03 | Estructura de colector hidráulico compacto para fluidos sensibles a cizalladura |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9421315B2 (https=) |
| EP (1) | EP2892585B1 (https=) |
| JP (1) | JP6614974B2 (https=) |
| ES (1) | ES2719615T3 (https=) |
| WO (1) | WO2014039441A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10702647B2 (en) | 2015-03-10 | 2020-07-07 | Viatar LLC | Systems, methods, and devices for removing circulating tumor cells from blood |
| US10876088B2 (en) | 2016-02-04 | 2020-12-29 | Massachusetts Institute Of Technology | Modular organ microphysiological system with integrated pumping, leveling, and sensing |
| CA3026485A1 (en) | 2016-06-06 | 2017-12-14 | The Charles Stark Draper Laboratory, Inc. | Systems and methods for cell transduction |
| JP6919215B2 (ja) * | 2017-02-17 | 2021-08-18 | ソニーグループ株式会社 | マイクロチップ及び微小粒子分取装置 |
| US12065635B2 (en) | 2018-03-19 | 2024-08-20 | Massachusetts Institute Of Technology | Organ-on-chip platforms with reduced fluid volume |
| AU2019305092A1 (en) * | 2018-07-19 | 2021-03-11 | Platelet Biogenesis, Inc. | Stacked recirculating bioreactor |
| CA3107096A1 (en) * | 2018-08-03 | 2020-02-06 | Yoram Palti | Distributed fluid-flow systems with equalized flow rate |
| EP3646903A1 (en) * | 2018-10-29 | 2020-05-06 | Centre National De La Recherche Scientifique | Microfluidic gas exchange devices and methods for making them |
| EP4404990A1 (en) * | 2021-09-20 | 2024-07-31 | Jeffrey T. Borenstein | Respiratory assist and fluid removal device for treatment of respiratory distress syndrome |
| US12303630B2 (en) | 2022-07-25 | 2025-05-20 | William M. Gosney | Apparatus utilizing electric field for processing of blood to neutralize pathogen cells therein |
| US12544497B2 (en) | 2022-07-25 | 2026-02-10 | Blood Image Technology Llc | Method of operation utilizing electric field for processing of blood to neutralize pathogen cells therein |
| US12467844B2 (en) | 2022-07-25 | 2025-11-11 | William M. Gosney | Method of operation utilizing venting for processing of blood to remove pathogen cells therein |
| US20240024557A1 (en) * | 2022-07-25 | 2024-01-25 | William M. Gosney | Cassette apparatus for processing of blood to neutralize pathogen cells therein |
| US12508355B2 (en) | 2022-07-25 | 2025-12-30 | Blood Image Technology Llc | Apparatus utilizing electric energy for processing of blood to neutralize pathogen cells therein |
| US12514969B2 (en) | 2022-07-25 | 2026-01-06 | William M. Gosney | Method of operation for processing of blood to neutralize pathogen cells therein |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2734224A (en) | 1956-02-14 | winstead | ||
| US3074559A (en) * | 1958-03-17 | 1963-01-22 | Savino Martino Francisco | Dialyzer chamber with capillary system |
| DE6801138U (de) | 1968-10-04 | 1969-03-20 | J Dr Med Hoeltzenbein | Dialysator |
| US3695445A (en) * | 1969-04-24 | 1972-10-03 | Becton Dickinson Co | Pleated membrane transfer device |
| US3585131A (en) * | 1969-04-24 | 1971-06-15 | Becton Dickinson Co | Pleated memberane exchange device |
| JPS521195Y2 (https=) * | 1971-10-07 | 1977-01-12 | ||
| US4038191A (en) * | 1975-10-14 | 1977-07-26 | Davis Harold R | Manifold for ultra filtration machine |
| US4110220A (en) * | 1976-10-18 | 1978-08-29 | Lavender Ardis R | Mass transfer device |
| US4980068A (en) * | 1983-08-15 | 1990-12-25 | Lavender Ardis R | System, apparatus and method for continuously fractionating blood in situ |
| US4980054A (en) * | 1983-08-15 | 1990-12-25 | Lavender Ardis R | System and method for mass transfer between fluids |
| US6601613B2 (en) * | 1998-10-13 | 2003-08-05 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
| US7316780B1 (en) * | 1999-01-29 | 2008-01-08 | Pall Corporation | Range separation devices and processes |
| US7759113B2 (en) | 1999-04-30 | 2010-07-20 | The General Hospital Corporation | Fabrication of tissue lamina using microfabricated two-dimensional molds |
| DE19961257C2 (de) | 1999-12-18 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Mikrovermischer |
| US7776021B2 (en) * | 2000-04-28 | 2010-08-17 | The Charles Stark Draper Laboratory | Micromachined bilayer unit for filtration of small molecules |
| AU2002239810A1 (en) | 2001-01-02 | 2002-07-16 | The Charles Stark Draper Laboratory, Inc. | Tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology |
| CA2472945A1 (en) * | 2002-02-13 | 2003-08-21 | Nanostream, Inc. | Microfluidic separation column devices and fabrication methods |
| US8147562B2 (en) | 2002-09-23 | 2012-04-03 | The General Hospital Corporation | Three dimensional construct for the design and fabrication of physiological fluidic networks |
| US8828226B2 (en) * | 2003-03-01 | 2014-09-09 | The Trustees Of Boston University | System for assessing the efficacy of stored red blood cells using microvascular networks |
| US20050020557A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors |
| EP1547676A1 (en) * | 2003-12-24 | 2005-06-29 | Corning Incorporated | Porous membrane microstructure devices and methods of manufacture |
| KR20070083967A (ko) | 2004-10-06 | 2007-08-24 | 더 스테이트 오브 오레곤 액팅 바이 앤드 쓰루 더 스테이트 보드 오브 하이어 에쥬케이션 온 비해프 오브 오레곤 스테이트 유니버시티 | Ｍｅｃｓ 투석기 |
| JP5368305B2 (ja) | 2006-08-24 | 2013-12-18 | フレゼニウス メディカル ケア ホールディングス インコーポレーテッド | 患者の血液から液体を除去するためのデバイス |
| WO2008127732A2 (en) | 2007-04-12 | 2008-10-23 | The General Hospital Corporation | Biomimetic vascular network and devices using the same |
| EP2200931B1 (en) | 2007-09-19 | 2017-06-07 | The Charles Stark Draper Laboratory, Inc. | Microfluidic structures with circular cross-section |
| US8188416B2 (en) * | 2008-01-14 | 2012-05-29 | The Charles Stark Draper Laboratory, Inc. | Engineered phantoms for perfusion imaging applications |
| CA3060930C (en) | 2008-06-06 | 2022-03-22 | Bionanomatrix, Inc. | Integrated analysis devices and related fabrication methods and analysis techniques |
| US20100125235A1 (en) * | 2008-06-16 | 2010-05-20 | Triaxis Medical Devices, Inc. | Blood Treatment Apparatus Having Branched Flow Distribution |
| US8801922B2 (en) * | 2009-06-24 | 2014-08-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Dialysis system |
| JP5879267B2 (ja) * | 2009-10-29 | 2016-03-08 | ザ・チャールズ・スターク・ドレイパ・ラボラトリー・インコーポレイテッド | 血液透析用マイクロ流体装置 |
| JP2013534461A (ja) | 2010-05-26 | 2013-09-05 | ザ チャールズ スターク ドレイパー ラボラトリー インク | 微細加工された人工肺補助装置ならびにその使用および製造の方法 |
-
2012
- 2012-09-05 US US13/604,256 patent/US9421315B2/en active Active
-
2013
- 2013-09-03 ES ES13765553T patent/ES2719615T3/es active Active
- 2013-09-03 JP JP2015531144A patent/JP6614974B2/ja active Active
- 2013-09-03 EP EP13765553.6A patent/EP2892585B1/en active Active
- 2013-09-03 WO PCT/US2013/057842 patent/WO2014039441A1/en not_active Ceased
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2016
- 2016-04-08 US US15/094,623 patent/US10071193B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2892585A1 (en) | 2015-07-15 |
| EP2892585B1 (en) | 2019-01-09 |
| JP6614974B2 (ja) | 2019-12-04 |
| US20140061115A1 (en) | 2014-03-06 |
| US9421315B2 (en) | 2016-08-23 |
| JP2015529155A (ja) | 2015-10-05 |
| US20160220961A1 (en) | 2016-08-04 |
| WO2014039441A1 (en) | 2014-03-13 |
| US10071193B2 (en) | 2018-09-11 |
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