ES2691094T3 - Nuevos copolímeros basados en poli(etilenimina) para el enlace y liberación de material genético, particularmente de ADN/ARN, así como método para su fabricación y uso - Google Patents
Nuevos copolímeros basados en poli(etilenimina) para el enlace y liberación de material genético, particularmente de ADN/ARN, así como método para su fabricación y uso Download PDFInfo
- Publication number
- ES2691094T3 ES2691094T3 ES14803038.0T ES14803038T ES2691094T3 ES 2691094 T3 ES2691094 T3 ES 2691094T3 ES 14803038 T ES14803038 T ES 14803038T ES 2691094 T3 ES2691094 T3 ES 2691094T3
- Authority
- ES
- Spain
- Prior art keywords
- ethyleneimine
- poly
- release
- genetic material
- units
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
- C08G73/0213—Preparatory process
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0233—Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102013016750.7A DE102013016750B4 (de) | 2013-10-02 | 2013-10-02 | Neue Poly(ethylenimin) basierte Copolymere zur Anbindung und Freisetzung von genetischem Material, insbesondere von DNA/RNA, sowie Verfahren zu deren Herstellung und Verwendung |
| DE102013016750 | 2013-10-02 | ||
| PCT/DE2014/000500 WO2015048940A1 (de) | 2013-10-02 | 2014-10-02 | Neue poly(ethylenimin) basierte copolymere zur anbindung und freisetzung von genetischem material, insbesondere von dna/rna, sowie verfahren zu deren herstellung und verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2691094T3 true ES2691094T3 (es) | 2018-11-23 |
Family
ID=51986963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14803038.0T Active ES2691094T3 (es) | 2013-10-02 | 2014-10-02 | Nuevos copolímeros basados en poli(etilenimina) para el enlace y liberación de material genético, particularmente de ADN/ARN, así como método para su fabricación y uso |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10131747B2 (enExample) |
| EP (1) | EP3052545B1 (enExample) |
| JP (1) | JP6431533B2 (enExample) |
| CN (1) | CN105683256B (enExample) |
| CA (1) | CA2926154C (enExample) |
| DE (1) | DE102013016750B4 (enExample) |
| DK (1) | DK3052545T3 (enExample) |
| ES (1) | ES2691094T3 (enExample) |
| HU (1) | HUE040402T2 (enExample) |
| WO (1) | WO2015048940A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101892955B1 (ko) | 2017-01-25 | 2018-08-29 | 국방과학연구소 | 치환된 Poly[2-(3-butenyl)-2-oxazoline] 및 Nylon-6,6를 포함하는 섬유 및 그 제조방법 |
| JP2023548450A (ja) * | 2020-10-19 | 2023-11-17 | ウニヴェルズィテート ゲント | 架橋可能なアリルアミドポリマー |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3251778A (en) | 1960-08-04 | 1966-05-17 | Petrolite Corp | Process of preventing scale |
| DE19726186A1 (de) * | 1997-06-20 | 1998-12-24 | Boehringer Ingelheim Int | Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen |
| DE10029028A1 (de) * | 2000-06-13 | 2001-12-20 | Basf Ag | Verwendung von acylierten Polyaminen zur Modifizierung von Oberflächen |
| DE20122328U1 (de) * | 2001-12-07 | 2006-02-09 | Sandler Ag | Neue modifizierte Poly-2-oxazoline |
| JP4368183B2 (ja) * | 2003-11-06 | 2009-11-18 | 財団法人川村理化学研究所 | ポリイオン会合体およびポリイオン会合体からなる生体物質キャリアー |
| US20050238825A1 (en) * | 2004-04-26 | 2005-10-27 | Isp Investments Inc. | Crosslinked polymeric composition |
| DE102005039154A1 (de) * | 2005-08-17 | 2007-03-01 | GÖPFERICH, Achim, Prof. Dr. | Bioabbaubare Polymere für den Transport von Nukleinsäuren in Zellen |
| US20070231392A1 (en) | 2006-01-23 | 2007-10-04 | Ernst Wagner | CHEMICALLY MODIFIED POLYCATION POLYMER FOR siRNA DELIVERY |
| EP2247645B1 (en) | 2008-02-13 | 2017-12-06 | Hyperbranch Medical Technology, Inc. | Crosslinked polyalkyleneimine hydrogels with tunable degradation rates |
| EP2310440A4 (en) * | 2008-07-10 | 2013-06-05 | Serina Therapeutics Inc | POLYOXAZOLINES WITH INTERNAL END GROUPS, POLYOXAZOLINES MANUFACTURED FROM PROTECTED INITIAL GROUPS AND CORRESPONDING COMPOUNDS |
| CN101768276B (zh) * | 2008-12-26 | 2011-11-30 | 中国科学技术大学 | 聚乙二醇单甲醚-聚己内酯-聚乙烯亚胺三嵌段共聚物及其应用 |
| KR20130139749A (ko) | 2010-06-25 | 2013-12-23 | 도레이 카부시키가이샤 | 수용성 중합체 및 수용성 나노입자 복합체 |
| BR112013017140B1 (pt) * | 2011-01-04 | 2019-12-17 | Bender Analytical Holding Bv | polímeros reticulados e implantes provenientes de polioxazolina eletrofilicamente ativada |
| CA2828797C (en) * | 2011-03-11 | 2020-03-10 | Gore Enterprise Holdings, Inc. | Single point attachment of heparin to hyperbranched polymers and coatings thereof |
| AT511386B1 (de) | 2011-05-03 | 2013-03-15 | Ke Kelit Kunststoffwerk Gmbh | Kontaktbiozid |
| US9416228B2 (en) * | 2012-03-16 | 2016-08-16 | Bender Analytical Holding B.V. | Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline |
-
2013
- 2013-10-02 DE DE102013016750.7A patent/DE102013016750B4/de active Active
-
2014
- 2014-10-02 DK DK14803038.0T patent/DK3052545T3/en active
- 2014-10-02 EP EP14803038.0A patent/EP3052545B1/de active Active
- 2014-10-02 CA CA2926154A patent/CA2926154C/en active Active
- 2014-10-02 US US15/026,882 patent/US10131747B2/en active Active
- 2014-10-02 CN CN201480059919.6A patent/CN105683256B/zh active Active
- 2014-10-02 JP JP2016519856A patent/JP6431533B2/ja active Active
- 2014-10-02 HU HUE14803038A patent/HUE040402T2/hu unknown
- 2014-10-02 WO PCT/DE2014/000500 patent/WO2015048940A1/de not_active Ceased
- 2014-10-02 ES ES14803038.0T patent/ES2691094T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10131747B2 (en) | 2018-11-20 |
| CA2926154A1 (en) | 2015-04-09 |
| HUE040402T2 (hu) | 2019-03-28 |
| JP6431533B2 (ja) | 2018-11-28 |
| WO2015048940A1 (de) | 2015-04-09 |
| CA2926154C (en) | 2022-08-30 |
| JP2016533409A (ja) | 2016-10-27 |
| US20170166697A1 (en) | 2017-06-15 |
| DE102013016750B4 (de) | 2026-07-30 |
| CN105683256B (zh) | 2018-02-23 |
| DK3052545T3 (en) | 2018-10-29 |
| EP3052545B1 (de) | 2018-07-25 |
| EP3052545A1 (de) | 2016-08-10 |
| DE102013016750A1 (de) | 2015-04-02 |
| CN105683256A (zh) | 2016-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Malik et al. | Cross-linked β-cyclodextrin and carboxymethyl cellulose hydrogels for controlled drug delivery of acyclovir | |
| Li et al. | Self-assembly and applications of poly (glycidyl methacrylate) s and their derivatives | |
| Zurick et al. | Recent biomedical advances with polyampholyte polymers | |
| Yang et al. | pH-sensitive interpenetrating network hydrogels based on chitosan derivatives and alginate for oral drug delivery | |
| Chivers et al. | Spatially-resolved soft materials for controlled release–hybrid hydrogels combining a robust photo-activated polymer gel with an interactive supramolecular gel | |
| Zhao et al. | In situ cross-linking of stimuli-responsive hemicellulose microgels during spray drying | |
| Roth et al. | UCST-driven self-assembly and crosslinking of diblock copolymer micelles | |
| Guaresti et al. | Light-driven assembly of biocompatible fluorescent chitosan hydrogels with self-healing ability | |
| Englert et al. | Linear poly (ethylene imine)-based hydrogels for effective binding and release of DNA | |
| Yu et al. | Biodegradable inorganic–organic POSS–PEG hybrid hydrogels as scaffolds for tissue engineering | |
| Chantasirichot et al. | Amphiphilic triblock phospholipid copolymers bearing phenylboronic acid groups for spontaneous formation of hydrogels with tunable mechanical properties | |
| Singh et al. | Ultrasmall sulfur‐dots‐mediated facile photopolymerization for the production of smart injectable ink for 3D printing applications | |
| WO2021035030A1 (en) | Surface functionalized substrates and methods of making the same | |
| Panic et al. | Methacrylic acid based polymer networks with a high content of unfunctionalized nanosilica: particle distribution, swelling, and rheological properties | |
| Zhang et al. | Saltwater‐induced rapid gelation of photoredox‐responsive mucomimetic hydrogels | |
| Liu et al. | A novel pH‐sensitive hydrogels for potential colon‐specific drug delivery: Characterization and in vitro release studies | |
| Chen et al. | Reductant-triggered rapid self-gelation and biological functionalization of hydrogels | |
| Shi et al. | Polyelectrolyte complex beads composed of water‐soluble chitosan/alginate: Characterization and their protein release behavior | |
| Barz et al. | Synthesis, characterization and preliminary biological evaluation of P (HPMA)‐b‐P (LLA) copolymers: a new type of functional biocompatible block copolymer | |
| Gurgel et al. | A Comprehensive Review on Core‐Shell Polymeric Particles for Enzyme Immobilization | |
| DK3052545T3 (en) | New poly (ethyleneimine) -based copolymers for binding to and releasing genetic material, especially DNA / RNA, and methods for their preparation and use | |
| Huang et al. | Micelles with a Loose Core Self‐Assembled from Coil‐g‐Rod Graft Copolymers Displaying High Drug Loading Capacity | |
| Wong et al. | Grafted copolymerized chitosan and its applications as a green biopolymer | |
| Nam et al. | Synthesis and characterization of a multi‐sensitive crosslinked injectable hydrogel based on pluronic | |
| McClellan et al. | RAFT polymerization for the synthesis of tertiary amine‐based diblock copolymer nucleic acid delivery vehicles |