ES2674239T8 - Medios para células madre pluripotentes carentes de alimentadores que contienen suero humano - Google Patents
Medios para células madre pluripotentes carentes de alimentadores que contienen suero humanoInfo
- Publication number
- ES2674239T8 ES2674239T8 ES08840374T ES08840374T ES2674239T8 ES 2674239 T8 ES2674239 T8 ES 2674239T8 ES 08840374 T ES08840374 T ES 08840374T ES 08840374 T ES08840374 T ES 08840374T ES 2674239 T8 ES2674239 T8 ES 2674239T8
- Authority
- ES
- Spain
- Prior art keywords
- stem cells
- human serum
- pluripotent stem
- containing human
- cells lacking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
- C12N5/068—Stem cells; Progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/98—Xeno-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US875057 | 1978-02-06 | ||
| US11/875,057 US8623650B2 (en) | 2007-10-19 | 2007-10-19 | Methods and compositions for feeder-free pluripotent stem cell media containing human serum |
| PCT/US2008/080516 WO2009052505A1 (en) | 2007-10-19 | 2008-10-20 | Feeder-free pluripotent stem cell media containing human serum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2674239T3 ES2674239T3 (es) | 2018-06-28 |
| ES2674239T8 true ES2674239T8 (es) | 2019-01-16 |
Family
ID=40563869
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18171601T Active ES2971288T3 (es) | 2007-10-19 | 2008-10-20 | Sistema de cultivo sin alimentador |
| ES08840374.6T Active ES2674239T3 (es) | 2007-10-19 | 2008-10-20 | Medios para células madre pluripotentes carentes de alimentadores que contienen suero humano |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18171601T Active ES2971288T3 (es) | 2007-10-19 | 2008-10-20 | Sistema de cultivo sin alimentador |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US8623650B2 (es) |
| EP (3) | EP2215214B1 (es) |
| CN (2) | CN101903515B (es) |
| AU (1) | AU2008311798B2 (es) |
| CA (1) | CA2703116C (es) |
| DK (1) | DK3375867T3 (es) |
| ES (2) | ES2971288T3 (es) |
| IL (5) | IL283597B2 (es) |
| PL (1) | PL2215214T3 (es) |
| WO (1) | WO2009052505A1 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7432104B2 (en) * | 2001-08-06 | 2008-10-07 | Bresgen Inc. | Methods for the culture of human embryonic stem cells on human feeder cells |
| CA2576872C (en) | 2004-08-13 | 2013-11-12 | University Of Georgia Research Foundation, Inc. | Compositions and methods for self-renewal and differentiation in human embryonic stem cells |
| EP2420565B1 (en) | 2006-02-23 | 2017-08-30 | ViaCyte, Inc. | Compositions and methods useful for culturing differentiable cells |
| US8623650B2 (en) | 2007-10-19 | 2014-01-07 | Viacyte, Inc. | Methods and compositions for feeder-free pluripotent stem cell media containing human serum |
| US8338170B2 (en) | 2008-04-21 | 2012-12-25 | Viacyte, Inc. | Methods for purifying endoderm and pancreatic endoderm cells derived from human embryonic stem cells |
| US20090298178A1 (en) * | 2008-06-03 | 2009-12-03 | D Amour Kevin Allen | Growth factors for production of definitive endoderm |
| US8008075B2 (en) | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
| US8895300B2 (en) | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| ES2932850T3 (es) | 2008-11-14 | 2023-01-27 | Viacyte Inc | Encapsulación de células pancreáticas derivadas de células madre pluripotentes humanas |
| US9109245B2 (en) | 2009-04-22 | 2015-08-18 | Viacyte, Inc. | Cell compositions derived from dedifferentiated reprogrammed cells |
| EP4166652A1 (en) | 2009-11-12 | 2023-04-19 | Technion Research & Development Foundation Ltd. | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
| WO2012115619A1 (en) | 2011-02-21 | 2012-08-30 | Viacyte, Inc. | Loading system for an encapsulation device |
| JOP20200043A1 (ar) | 2011-05-10 | 2017-06-16 | Amgen Inc | طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول |
| AU2013248265B2 (en) * | 2012-11-08 | 2018-11-01 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| CN116212115A (zh) | 2013-03-07 | 2023-06-06 | 韦尔赛特公司 | 三维大容量细胞包封装置组件 |
| USD720469S1 (en) | 2013-03-07 | 2014-12-30 | Viacyte, Inc. | Cell encapsulation device |
| US8859286B2 (en) | 2013-03-14 | 2014-10-14 | Viacyte, Inc. | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells |
| KR102232650B1 (ko) | 2013-06-11 | 2021-03-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
| US11051900B2 (en) | 2014-04-16 | 2021-07-06 | Viacyte, Inc. | Tools and instruments for use with implantable encapsulation devices |
| CN107614678B (zh) | 2014-12-18 | 2021-04-30 | 哈佛学院校长同事会 | 干细胞来源的β细胞的产生方法及其使用方法 |
| ES2985135T3 (es) | 2014-12-18 | 2024-11-04 | Harvard College | Procedimientos para generar células ß derivadas de células madre y usos de las mismas |
| WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
| CN118924958A (zh) | 2016-11-10 | 2024-11-12 | 韦尔赛特公司 | 含有pdx1胰腺内胚层细胞的细胞递送装置及其方法 |
| CN111565707A (zh) | 2017-06-14 | 2020-08-21 | 森玛治疗公司 | 用于递送治疗物的装置和方法 |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| AU2018370029B2 (en) | 2017-11-15 | 2024-11-07 | Vertex Pharmaceuticals Incorporated | Islet cell manufacturing compositions and methods of use |
| WO2020033879A1 (en) | 2018-08-10 | 2020-02-13 | Semma Therapeutics, Inc. | Stem cell derived islet differentiation |
| US12378572B2 (en) | 2018-09-07 | 2025-08-05 | Crispr Therapeutics Ag | Universal donor cells |
| CN110373375A (zh) * | 2019-03-19 | 2019-10-25 | 杭州原生生物科技有限公司 | 一种制备纤维细胞作为细胞培养基的方法和用途 |
| AU2020283056B2 (en) | 2019-05-31 | 2023-06-08 | Viacyte, Inc. | A biocompatible membrane composite |
| AU2020282355B2 (en) | 2019-05-31 | 2023-11-02 | Viacyte, Inc. | A biocompatible membrane composite |
| WO2020243666A1 (en) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
| CA3139292C (en) | 2019-05-31 | 2025-06-10 | Viacyte, Inc. | CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES |
| US20210060163A1 (en) * | 2019-09-04 | 2021-03-04 | Vcell Therapeutics, Inc. | Vaccine for treatment of cancer and method of making by stress reprogramming |
| KR20220058579A (ko) | 2019-09-05 | 2022-05-09 | 크리스퍼 테라퓨틱스 아게 | 보편적 공여자 세포 |
| US11118196B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
| WO2022144856A1 (en) | 2020-12-31 | 2022-07-07 | Crispr Therapeutics Ag | Universal donor cells |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4309418A (en) | 1980-03-25 | 1982-01-05 | Sloan-Kettering Research Institute For Cancer | Anti-tumor agent from human serum and process |
| US5453357A (en) | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| JP2001517927A (ja) | 1996-02-28 | 2001-10-09 | バンダービルト ユニバーシティ | 胚幹細胞を作製する組成物および方法 |
| US6331406B1 (en) | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| CA2307807C (en) | 1997-10-23 | 2008-09-02 | Andrea G. Bodnar | Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture |
| NZ507103A (en) | 1998-04-09 | 2002-10-25 | Bresagen Ltd | Cell differentiation/proliferation and maintenance factor and uses thereof |
| JP2002529070A (ja) | 1998-11-09 | 2002-09-10 | モナシュ・ユニヴァーシティ | 胚性幹細胞 |
| GB2396623B (en) * | 2001-09-28 | 2006-04-05 | Es Cell Int Pte Ltd | Methods of derivation and propagation of undifferentiated human embryonic stem (hes) cells on feeder-free matrices and human feeder layers |
| HUE028026T2 (en) * | 2002-12-16 | 2016-11-28 | Technion Res & Dev Foundation | Breeding system free of native cells, free of foreign matter for human embryonic stem cells |
| US8647873B2 (en) | 2004-04-27 | 2014-02-11 | Viacyte, Inc. | PDX1 expressing endoderm |
| US7625753B2 (en) | 2003-12-23 | 2009-12-01 | Cythera, Inc. | Expansion of definitive endoderm cells |
| WO2005065354A2 (en) | 2003-12-31 | 2005-07-21 | The Burnham Institute | Defined media for pluripotent stem cell culture |
| CN101048495A (zh) * | 2004-04-27 | 2007-10-03 | 赛瑟拉公司 | 表达pdx1的内胚层 |
| CN101023163A (zh) * | 2004-07-09 | 2007-08-22 | 赛瑟拉公司 | 鉴定用于分化定型内胚层的因子的方法 |
| US8597947B2 (en) * | 2004-12-29 | 2013-12-03 | Hadasit Medical Research Services & Development Limited | Undifferentiated stem cell culture systems |
| US20070122392A1 (en) | 2005-06-22 | 2007-05-31 | Sharon Gerecht-Nir | Propagation of undifferentiated embryonic stem cells in hyaluronic acid hydrogel |
| EP2420565B1 (en) * | 2006-02-23 | 2017-08-30 | ViaCyte, Inc. | Compositions and methods useful for culturing differentiable cells |
| US7964402B2 (en) * | 2006-05-25 | 2011-06-21 | Sanford-Burnham Medical Research Institute | Methods for culture and production of single cell populations of human embryonic stem cells |
| DK2634242T3 (en) * | 2006-07-14 | 2017-05-22 | Patheon Holdings I B V | IMPROVED PROCEDURE FOR CULTURING CELLS |
| US8623650B2 (en) | 2007-10-19 | 2014-01-07 | Viacyte, Inc. | Methods and compositions for feeder-free pluripotent stem cell media containing human serum |
-
2007
- 2007-10-19 US US11/875,057 patent/US8623650B2/en active Active
-
2008
- 2008-10-20 IL IL283597A patent/IL283597B2/en unknown
- 2008-10-20 CA CA2703116A patent/CA2703116C/en active Active
- 2008-10-20 ES ES18171601T patent/ES2971288T3/es active Active
- 2008-10-20 EP EP08840374.6A patent/EP2215214B1/en active Active
- 2008-10-20 CN CN200880121734.8A patent/CN101903515B/zh active Active
- 2008-10-20 EP EP18171601.0A patent/EP3375867B1/en active Active
- 2008-10-20 IL IL297378A patent/IL297378B2/en unknown
- 2008-10-20 AU AU2008311798A patent/AU2008311798B2/en active Active
- 2008-10-20 ES ES08840374.6T patent/ES2674239T3/es active Active
- 2008-10-20 PL PL08840374T patent/PL2215214T3/pl unknown
- 2008-10-20 CN CN201410640785.9A patent/CN104498432B/zh active Active
- 2008-10-20 WO PCT/US2008/080516 patent/WO2009052505A1/en not_active Ceased
- 2008-10-20 EP EP24152287.9A patent/EP4368701A3/en active Pending
- 2008-10-20 DK DK18171601.0T patent/DK3375867T3/da active
-
2010
- 2010-04-15 IL IL205115A patent/IL205115A/en active IP Right Grant
- 2010-08-15 US US12/856,662 patent/US8334138B2/en active Active
-
2013
- 2013-12-10 US US14/102,451 patent/US9267110B2/en active Active
-
2015
- 2015-04-21 IL IL238395A patent/IL238395B/en active IP Right Grant
-
2016
- 2016-02-22 US US15/050,069 patent/US10246680B2/en active Active
-
2019
- 2019-04-01 US US16/372,358 patent/US10808223B2/en active Active
- 2019-06-16 IL IL267371A patent/IL267371B/en active IP Right Grant
-
2020
- 2020-10-19 US US17/074,481 patent/US11920154B2/en active Active
-
2023
- 2023-09-26 US US18/373,014 patent/US20240218324A1/en active Pending
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