ES2669208T3 - Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma - Google Patents

Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma Download PDF

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ES2669208T3
ES2669208T3 ES15700613.1T ES15700613T ES2669208T3 ES 2669208 T3 ES2669208 T3 ES 2669208T3 ES 15700613 T ES15700613 T ES 15700613T ES 2669208 T3 ES2669208 T3 ES 2669208T3
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substituted
cr2er2f
alkyl
hydrogen
independently
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Jingwu Duan
T.G. Murali Dhar
Bin Jiang
Zhonghui Lu
Hai-Yun Xiao
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Bristol Myers Squibb Co
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Immunology (AREA)
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  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES15700613.1T 2014-01-06 2015-01-05 Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma Active ES2669208T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461923896P 2014-01-06 2014-01-06
US201461923896P 2014-01-06
PCT/US2015/010089 WO2015103509A1 (en) 2014-01-06 2015-01-05 Pyrrolidinyl sulfone derivatives and their use as ror gamma modulators

Publications (1)

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ES2669208T3 true ES2669208T3 (es) 2018-05-24

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US (2) US20160326108A1 (en:Method)
EP (1) EP3092229B1 (en:Method)
JP (1) JP6530764B2 (en:Method)
CN (1) CN106061971B (en:Method)
AR (1) AR099029A1 (en:Method)
CA (1) CA2936116A1 (en:Method)
EA (1) EA030849B1 (en:Method)
ES (1) ES2669208T3 (en:Method)
MX (1) MX369347B (en:Method)
TW (1) TW201609634A (en:Method)
WO (1) WO2015103509A1 (en:Method)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015035278A1 (en) 2013-09-09 2015-03-12 Bristol-Myers Squibb Company RORγ MODULATORS
EP3046906B1 (en) 2013-09-20 2017-08-16 Bristol-Myers Squibb Company Ror gamma modulators
EP3092221B1 (en) 2014-01-06 2018-10-17 Bristol-Myers Squibb Company Heterocyclic sulfones as ror-gamma modulators
US9771320B2 (en) 2014-01-06 2017-09-26 Bristol-Myers Squibb Company Carbocyclic sulfone RORγ modulators
EP3092215B1 (en) * 2014-01-06 2018-10-17 Bristol-Myers Squibb Company Cyclohexyl sulfone ror gamma modulators
EP3212642B1 (en) 2014-10-30 2019-10-30 Janssen Pharmaceutica NV Amide substituted thiazoles as modulators of rorgammat
TWI667230B (zh) 2014-10-30 2019-08-01 比利時商健生藥品公司 用作ＲＯＲγｔ調節劑之三氟甲基醇
LT3212641T (lt) 2014-10-30 2019-02-11 Janssen Pharmaceutica Nv Tiazolai, kaip roryt moduliatoriai
KR102114536B1 (ko) 2015-05-07 2020-05-22 브리스톨-마이어스 스큅 컴퍼니 RORγ 조정제로서의 트리시클릭 술폰
US10610520B2 (en) 2016-03-31 2020-04-07 Takeda Pharmaceutical Company Limited Heterocyclic compound
TW201803869A (zh) 2016-04-27 2018-02-01 健生藥品公司 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑
KR20190057388A (ko) * 2016-10-10 2019-05-28 브리스톨-마이어스 스큅 컴퍼니 Ror 감마 조정제로서의 트리시클릭 술폰
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