ES2669208T3 - Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma - Google Patents

Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma Download PDF

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Publication number
ES2669208T3
ES2669208T3 ES15700613.1T ES15700613T ES2669208T3 ES 2669208 T3 ES2669208 T3 ES 2669208T3 ES 15700613 T ES15700613 T ES 15700613T ES 2669208 T3 ES2669208 T3 ES 2669208T3
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substituted
cr2er2f
alkyl
hydrogen
independently
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Spanish (es)
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Jingwu Duan
T.G. Murali Dhar
Bin Jiang
Zhonghui Lu
Hai-Yun Xiao
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
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    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Organic Chemistry (AREA)
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  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES15700613.1T 2014-01-06 2015-01-05 Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma Active ES2669208T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461923896P 2014-01-06 2014-01-06
US201461923896P 2014-01-06
PCT/US2015/010089 WO2015103509A1 (en) 2014-01-06 2015-01-05 Pyrrolidinyl sulfone derivatives and their use as ror gamma modulators

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EP (1) EP3092229B1 (US20070167479A1-20070719-C00034.png)
JP (1) JP6530764B2 (US20070167479A1-20070719-C00034.png)
CN (1) CN106061971B (US20070167479A1-20070719-C00034.png)
AR (1) AR099029A1 (US20070167479A1-20070719-C00034.png)
CA (1) CA2936116A1 (US20070167479A1-20070719-C00034.png)
EA (1) EA030849B1 (US20070167479A1-20070719-C00034.png)
ES (1) ES2669208T3 (US20070167479A1-20070719-C00034.png)
MX (1) MX369347B (US20070167479A1-20070719-C00034.png)
TW (1) TW201609634A (US20070167479A1-20070719-C00034.png)
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Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
JP6407285B2 (ja) 2013-09-09 2018-10-17 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ ＲＯＲγ調節因子
WO2015042212A1 (en) 2013-09-20 2015-03-26 Bristol-Myers Squibb Company RORγ MODULATORS
WO2015103508A1 (en) 2014-01-06 2015-07-09 Bristol-Myers Squibb Company CARBOCYCLIC SULFONE RORγ MODULATORS
WO2015103510A1 (en) 2014-01-06 2015-07-09 Bristol-Myers Squibb Company Heterocyclic sulfone as ror-gamma modulators
US9708253B2 (en) 2014-01-06 2017-07-18 Bristol-Myers Squibb Company Cyclohexyl sulfone RORγ modulators
JOP20200117A1 (ar) 2014-10-30 2017-06-16 Janssen Pharmaceutica Nv كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ROR?t
PT3212641T (pt) 2014-10-30 2019-02-11 Janssen Pharmaceutica Nv Tiazoles como moduladores de rorãt
MA40865B1 (fr) 2014-10-30 2019-11-29 Janssen Pharmaceutica Nv Thiazoles à substitution amide utilisés comme modulateurs de rorgammat
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