ES2662649T3 - Producto de fuente de hierro en forma de cápsulas y procedimiento para su preparación - Google Patents
Producto de fuente de hierro en forma de cápsulas y procedimiento para su preparación Download PDFInfo
- Publication number
- ES2662649T3 ES2662649T3 ES09783831.2T ES09783831T ES2662649T3 ES 2662649 T3 ES2662649 T3 ES 2662649T3 ES 09783831 T ES09783831 T ES 09783831T ES 2662649 T3 ES2662649 T3 ES 2662649T3
- Authority
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- Spain
- Prior art keywords
- iron
- capsules
- alginate
- salt
- food product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title claims abstract description 487
- 229910052742 iron Inorganic materials 0.000 title claims abstract description 242
- 239000002775 capsule Substances 0.000 title claims abstract description 227
- 238000000034 method Methods 0.000 title claims description 20
- 238000002360 preparation method Methods 0.000 title description 13
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims abstract description 58
- 235000010443 alginic acid Nutrition 0.000 claims abstract description 45
- 229920000615 alginic acid Polymers 0.000 claims abstract description 45
- 229940072056 alginate Drugs 0.000 claims abstract description 35
- 235000014106 fortified food Nutrition 0.000 claims abstract description 23
- 239000007787 solid Substances 0.000 claims abstract description 23
- 235000010410 calcium alginate Nutrition 0.000 claims abstract description 11
- 239000000648 calcium alginate Substances 0.000 claims abstract description 11
- 229960002681 calcium alginate Drugs 0.000 claims abstract description 11
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 81
- 235000013305 food Nutrition 0.000 claims description 68
- 235000013618 yogurt Nutrition 0.000 claims description 43
- 150000002505 iron Chemical class 0.000 claims description 41
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical group CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 34
- 235000010413 sodium alginate Nutrition 0.000 claims description 34
- 239000000661 sodium alginate Substances 0.000 claims description 34
- 229940005550 sodium alginate Drugs 0.000 claims description 34
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- 239000008267 milk Substances 0.000 claims description 29
- WXOMTJVVIMOXJL-BOBFKVMVSA-A O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)OS(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS(=O)(=O)O[Al](O)O)O[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]2OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]1OS(=O)(=O)O[Al](O)O Chemical compound O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)OS(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS(=O)(=O)O[Al](O)O)O[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]2OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]1OS(=O)(=O)O[Al](O)O WXOMTJVVIMOXJL-BOBFKVMVSA-A 0.000 claims description 23
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 35
- JARKCYVAAOWBJS-UHFFFAOYSA-N hexanal Chemical compound CCCCCC=O JARKCYVAAOWBJS-UHFFFAOYSA-N 0.000 description 34
- 238000003860 storage Methods 0.000 description 31
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 23
- 241001465754 Metazoa Species 0.000 description 22
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 21
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 21
- 239000002245 particle Substances 0.000 description 21
- 239000002609 medium Substances 0.000 description 17
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- 235000003891 ferrous sulphate Nutrition 0.000 description 12
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- 150000001768 cations Chemical class 0.000 description 10
- -1 iron cation Chemical class 0.000 description 10
- 239000010410 layer Substances 0.000 description 10
- 229960001126 alginic acid Drugs 0.000 description 9
- 239000000783 alginic acid Substances 0.000 description 9
- 150000004781 alginic acids Chemical class 0.000 description 9
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- 159000000014 iron salts Chemical class 0.000 description 7
- 239000013589 supplement Substances 0.000 description 7
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 6
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 6
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- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 5
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- MDXRFOWKIZPNTA-UHFFFAOYSA-L butanedioate;iron(2+) Chemical compound [Fe+2].[O-]C(=O)CCC([O-])=O MDXRFOWKIZPNTA-UHFFFAOYSA-L 0.000 description 4
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- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 3
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- FRHBOQMZUOWXQL-UHFFFAOYSA-L ammonium ferric citrate Chemical compound [NH4+].[Fe+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FRHBOQMZUOWXQL-UHFFFAOYSA-L 0.000 description 3
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Classifications
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1322—Inorganic compounds; Minerals, including organic salts thereof, oligo-elements; Amino-acids, peptides, protein-hydrolysates or derivatives; Nucleic acids or derivatives; Yeast extract or autolysate; Vitamins; Antibiotics; Bacteriocins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
- A23L33/165—Complexes or chelates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K33/24—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Dairy Products (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08166052 | 2008-10-08 | ||
| EP08166052A EP2174657A1 (en) | 2008-10-08 | 2008-10-08 | Iron source product in the form of capsules and process for their prepartion |
| US11426108P | 2008-11-13 | 2008-11-13 | |
| US114261P | 2008-11-13 | ||
| PCT/EP2009/063059 WO2010040789A1 (en) | 2008-10-08 | 2009-10-07 | Iron source product in the form of capsules and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2662649T3 true ES2662649T3 (es) | 2018-04-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09783831.2T Active ES2662649T3 (es) | 2008-10-08 | 2009-10-07 | Producto de fuente de hierro en forma de cápsulas y procedimiento para su preparación |
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|---|---|
| US (1) | US20110195147A1 (enExample) |
| EP (2) | EP2174657A1 (enExample) |
| JP (1) | JP5757528B2 (enExample) |
| KR (1) | KR20110075008A (enExample) |
| CN (1) | CN102176903B (enExample) |
| AR (1) | AR073415A1 (enExample) |
| BR (1) | BRPI0920228B1 (enExample) |
| CA (1) | CA2737401C (enExample) |
| CL (1) | CL2011000616A1 (enExample) |
| CO (1) | CO6361909A2 (enExample) |
| CY (1) | CY1119915T1 (enExample) |
| DK (1) | DK2349228T3 (enExample) |
| EC (1) | ECSP11010939A (enExample) |
| ES (1) | ES2662649T3 (enExample) |
| HR (1) | HRP20180144T1 (enExample) |
| HU (1) | HUE038130T2 (enExample) |
| LT (1) | LT2349228T (enExample) |
| MX (1) | MX2011003750A (enExample) |
| NO (1) | NO2349228T3 (enExample) |
| PE (1) | PE20110389A1 (enExample) |
| PL (1) | PL2349228T3 (enExample) |
| PT (1) | PT2349228T (enExample) |
| RU (1) | RU2491059C2 (enExample) |
| SI (1) | SI2349228T1 (enExample) |
| SM (1) | SMT201800132T1 (enExample) |
| UA (1) | UA104436C2 (enExample) |
| WO (1) | WO2010040789A1 (enExample) |
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| CN102589963B (zh) * | 2011-12-22 | 2013-11-27 | 攀钢集团攀枝花钢铁研究院有限公司 | 一种钛精矿、钛渣或碳化钛渣的消解方法和检测方法 |
| CN102940037B (zh) * | 2012-05-23 | 2014-06-04 | 四川农业大学 | 制备共沉淀氢氧化铁酸奶的方法 |
| ES2729839T3 (es) | 2012-06-01 | 2019-11-06 | Dsm Ip Assets Bv | Suplementación con minerales de bebidas |
| CN105377059A (zh) * | 2013-07-05 | 2016-03-02 | 雀巢产品技术援助有限公司 | 乳铁蛋白-骨桥蛋白-铁络合物 |
| RU2548777C2 (ru) * | 2013-07-09 | 2015-04-20 | Александр Александрович Кролевец | Способ получения частиц инкапсулированных жирорастворимой полимерной оболочкой солей металлов, обладающих супрамолекулярными свойствами |
| EP3086654A1 (en) * | 2013-12-27 | 2016-11-02 | Nestec S.A. | Composition comprising ferric saccharate and high concentrations of microencapsulated lc-pufa with a reduced off taste |
| US10863753B2 (en) | 2015-10-01 | 2020-12-15 | The Governing Council Of The University Of Toronto | Iron-fortified tea preparations and methods of making same |
| RU2623593C1 (ru) * | 2016-02-10 | 2017-06-28 | Александр Александрович Кролевец | Способ получения мармелада с повышенным содержанием железа |
| WO2020172623A1 (en) | 2019-02-21 | 2020-08-27 | Ingenuity Foods, Inc. | Compositions comprising choline and omega-3 fatty acid to nutritionally enhance food products |
| IT201900025393A1 (it) | 2019-12-23 | 2021-06-23 | Pharma Line S R L | Formulazione microincapsulata comprendente ferro e cistina, sue composizioni e loro uso per il trattamento di anemia o una deficienza di ferro |
| CN111493257A (zh) * | 2020-04-27 | 2020-08-07 | 郑州瑞普生物工程有限公司 | 一种蛋白固体饮料及其制备方法 |
| US11776118B2 (en) * | 2020-12-02 | 2023-10-03 | International Business Machines Corporation | Recognition of partially digested medications |
| GB2617580B (en) * | 2022-04-12 | 2024-05-22 | Foster & Freeman Ltd | Latent fingermark validation strips |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3228231A1 (de) * | 1982-07-28 | 1984-02-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Arzneimittel, calciummischsalze von polymeren, anionischen carbonsaeuren und/oder schwefelsaeureestern, verfahren zu ihrer herstellung und ihre verwendung |
| JPH03285654A (ja) * | 1990-03-30 | 1991-12-16 | Snow Brand Milk Prod Co Ltd | 機能性物質を高濃度に内包したカプセル体及びその製造法 |
| US20030190355A1 (en) * | 2002-04-05 | 2003-10-09 | Hermelin Marc S. | Modified release minerals |
| GB0310673D0 (en) * | 2003-05-09 | 2003-06-11 | Givaudan Sa | Alginate matrix particles |
| BR0305871B1 (pt) | 2003-11-24 | 2014-10-21 | Inst Pesquisas Tech | Produto à base de sulfato ferroso para fortificação de alimentos desidratados e método de preparação |
| RU2287302C2 (ru) * | 2004-05-13 | 2006-11-20 | Федеральное Государственное образовательное учреждение Высшего профессионального образования Вологодская государственная молочнохозяйственная академия им. Н.В. Верещагина | Способ обогащения минеральными веществами пищевого продукта |
| EP1743530B1 (en) * | 2005-07-15 | 2011-08-31 | Unilever N.V. | Iron fortified food product and additive |
| BRPI0716157A2 (pt) * | 2006-09-05 | 2013-09-17 | Ct Brasileiro De Pesquisa Fisica Cbpf | processo para produÇço microcÁpsulas dotadas de propriedades magnÉticas, produto obtido e mÉtodo para a liberaÇço controlada de substÂncias ativas |
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