ES2658155T3 - Procedimientos y formulaciones ectoparasiticidas - Google Patents
Procedimientos y formulaciones ectoparasiticidas Download PDFInfo
- Publication number
- ES2658155T3 ES2658155T3 ES10727315.3T ES10727315T ES2658155T3 ES 2658155 T3 ES2658155 T3 ES 2658155T3 ES 10727315 T ES10727315 T ES 10727315T ES 2658155 T3 ES2658155 T3 ES 2658155T3
- Authority
- ES
- Spain
- Prior art keywords
- spinetoram
- administration
- formulations
- pharmaceutically acceptable
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title description 24
- 238000009472 formulation Methods 0.000 title description 22
- 238000000034 method Methods 0.000 title description 10
- 230000001984 ectoparasiticidal effect Effects 0.000 title description 3
- 239000005929 Spinetoram Substances 0.000 claims abstract description 47
- GOENIMGKWNZVDA-OAMCMWGQSA-N Spinetoram Chemical compound CO[C@@H]1[C@H](OCC)[C@@H](OC)[C@H](C)O[C@H]1OC1C[C@H]2[C@@H]3C=C4C(=O)[C@H](C)[C@@H](O[C@@H]5O[C@H](C)[C@H](CC5)N(C)C)CCC[C@H](CC)OC(=O)CC4[C@@H]3CC[C@@H]2C1 GOENIMGKWNZVDA-OAMCMWGQSA-N 0.000 claims abstract description 47
- 150000003839 salts Chemical class 0.000 claims abstract description 22
- 241000282326 Felis catus Species 0.000 claims abstract description 18
- 208000006004 Flea Infestations Diseases 0.000 claims abstract description 6
- 238000011200 topical administration Methods 0.000 claims abstract description 3
- 241000258924 Ctenocephalides felis Species 0.000 claims description 14
- 239000007921 spray Substances 0.000 claims description 4
- 238000007654 immersion Methods 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 238000005507 spraying Methods 0.000 claims description 2
- 238000009736 wetting Methods 0.000 claims description 2
- 230000037396 body weight Effects 0.000 claims 1
- 238000011282 treatment Methods 0.000 description 22
- 241001465754 Metazoa Species 0.000 description 15
- 241000258242 Siphonaptera Species 0.000 description 13
- 206010061217 Infestation Diseases 0.000 description 11
- 239000000243 solution Substances 0.000 description 10
- 230000000699 topical effect Effects 0.000 description 10
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 9
- 244000078703 ectoparasite Species 0.000 description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- 239000002917 insecticide Substances 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 5
- WGYZMNBUZFHYRX-UHFFFAOYSA-N 1-(1-methoxypropan-2-yloxy)propan-2-ol Chemical compound COCC(C)OCC(C)O WGYZMNBUZFHYRX-UHFFFAOYSA-N 0.000 description 4
- JFLRKDZMHNBDQS-UCQUSYKYSA-N CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C Chemical compound CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C JFLRKDZMHNBDQS-UCQUSYKYSA-N 0.000 description 4
- 239000005930 Spinosad Substances 0.000 description 4
- 241000607479 Yersinia pestis Species 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 210000004209 hair Anatomy 0.000 description 4
- 239000000575 pesticide Substances 0.000 description 4
- 229940014213 spinosad Drugs 0.000 description 4
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 3
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 3
- 239000005899 Fipronil Substances 0.000 description 3
- 241000282412 Homo Species 0.000 description 3
- 235000019445 benzyl alcohol Nutrition 0.000 description 3
- 229960004217 benzyl alcohol Drugs 0.000 description 3
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 3
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- -1 conditioners Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 229940013764 fipronil Drugs 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 241000238876 Acari Species 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 241000255925 Diptera Species 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 2
- 239000005906 Imidacloprid Substances 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000011929 di(propylene glycol) methyl ether Substances 0.000 description 2
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940056881 imidacloprid Drugs 0.000 description 2
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000003359 percent control normalization Methods 0.000 description 2
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 2
- 229960000490 permethrin Drugs 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 229930185156 spinosyn Natural products 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- COVZYZSDYWQREU-UHFFFAOYSA-N Busulfan Chemical compound CS(=O)(=O)OCCCCOS(C)(=O)=O COVZYZSDYWQREU-UHFFFAOYSA-N 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N EtOH Substances CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010016675 Filariasis lymphatic Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 208000037263 Lymphatic filariasis Diseases 0.000 description 1
- 241000243985 Onchocerca volvulus Species 0.000 description 1
- 241001674048 Phthiraptera Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000011461 current therapy Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000013057 ectoparasiticide Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 208000005239 filarial elephantiasis Diseases 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 201000001371 inclusion conjunctivitis Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 208000003177 ocular onchocerciasis Diseases 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- VGGSULWDCMWZPO-ODEMIOGVSA-N spinosin Chemical class O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=2C(=O)C=C(OC=2C=C1OC)C=1C=CC(O)=CC=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VGGSULWDCMWZPO-ODEMIOGVSA-N 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940100613 topical solution Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 206010044325 trachoma Diseases 0.000 description 1
- 201000002311 trypanosomiasis Diseases 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N45/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring
- A01N45/02—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring having three carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21850209P | 2009-06-19 | 2009-06-19 | |
| US218502P | 2009-06-19 | ||
| US26225609P | 2009-11-18 | 2009-11-18 | |
| US262256P | 2009-11-18 | ||
| PCT/US2010/038768 WO2010148053A1 (en) | 2009-06-19 | 2010-06-16 | Ectoparasiticidal methods and formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2658155T3 true ES2658155T3 (es) | 2018-03-08 |
Family
ID=42657965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10727315.3T Active ES2658155T3 (es) | 2009-06-19 | 2010-06-16 | Procedimientos y formulaciones ectoparasiticidas |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8871727B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2442646B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5738853B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN104115831A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010260102B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2764401C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2658155T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL216441A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011014028A (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ596645A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2442646T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2442646T (cg-RX-API-DMAC7.html) |
| TW (1) | TWI510189B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010148053A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI510189B (zh) * | 2009-06-19 | 2015-12-01 | Lilly Co Eli | 殺外寄生蟲之方法及調配物 |
| BR112015009794A2 (pt) * | 2012-11-14 | 2017-07-11 | Lilly Co Eli | métodos e formulações ectoparasiticidas |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU711185B2 (en) * | 1995-06-14 | 1999-10-07 | Dow Agrosciences Llc | Synthetic modification to spinosyn compounds |
| US6001981A (en) | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
| ID29130A (id) | 1998-07-02 | 2001-08-02 | Lilly Co Eli | Formulasi pengendali kutu pada manusia |
| MXPA02001505A (es) | 1999-08-12 | 2002-07-02 | Lilly Co Eli | Tratamiento oral de animales de compania con spinosyns actoparasiticida. |
| US6933318B1 (en) | 1999-08-12 | 2005-08-23 | Eli Lilly And Company | Topical organic ectoparasiticidal formulations |
| CA2380643A1 (en) * | 1999-08-12 | 2001-02-22 | Eli Lilly And Company | Topical organic ectoparasiticidal formulations |
| US6927210B1 (en) | 1999-08-12 | 2005-08-09 | Eli Lilly And Company | Ectoparasiticidal aqueous suspension formulations of spinosyns |
| AU6606400A (en) | 1999-08-12 | 2001-03-13 | Eli Lilly And Company | Topical treatment for insect pests in companion animals |
| JP4666861B2 (ja) | 1999-09-13 | 2011-04-06 | ダウ・アグロサイエンス・エル・エル・シー | 有害生物防除性マクロライド |
| US6727228B2 (en) | 2001-04-25 | 2004-04-27 | Johnson & Johnson Consumer Companies, Inc. | Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs |
| BR0104024C1 (pt) * | 2001-09-13 | 2003-11-04 | Albrecht Equip Ind Ltda | Equipamento e processo para beneficiamento de tecidos em geral |
| EP2347654B1 (en) * | 2001-09-17 | 2019-02-27 | Elanco US Inc. | Formulation for controlling lice or ticks in catlle |
| DE102004025321A1 (de) * | 2004-05-19 | 2005-12-08 | Alstom Technology Ltd | Strömungsmaschinenschaufel |
| TW200740369A (en) * | 2005-11-01 | 2007-11-01 | Dow Agrosciences Llc | Pesticidally active compositions having enhanced activity |
| EP1849363A1 (en) * | 2006-03-09 | 2007-10-31 | Cheminova A/S | Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin |
| BRPI0710403A2 (pt) * | 2006-04-20 | 2011-08-09 | Du Pont | composto composição, composição de controle, de pulverização, de isca, dispositivo de armadilha, métodos de controle, métodos de proteção, semente tratada, composição de proteção |
| CN101917851B (zh) * | 2006-05-25 | 2014-02-12 | 美国陶氏益农公司 | 刺糖菌素熏蒸剂 |
| WO2007144786A2 (en) * | 2006-05-26 | 2007-12-21 | Entarco Sa | The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same |
| CN101535330B (zh) * | 2006-11-03 | 2012-06-27 | 陶氏益农公司 | 选择性还原多杀菌素因子et-j和et-l制备多虫菌素 |
| MX2009007482A (es) * | 2007-02-09 | 2009-08-13 | Pfizer Ltd | Agentes antiparasitarios. |
| JP5315818B2 (ja) * | 2007-07-12 | 2013-10-16 | 住友化学株式会社 | 有害生物防除組成物 |
| EP2033518A1 (en) | 2007-09-06 | 2009-03-11 | Cheminova A/S | Pesticidal compositions |
| JP2009132670A (ja) * | 2007-11-09 | 2009-06-18 | Sumitomo Chemical Co Ltd | 有害生物防除組成物 |
| JP2012500824A (ja) | 2008-08-28 | 2012-01-12 | ビーエーエスエフ ソシエタス・ヨーロピア | シアノスルホキシミン化合物とスピネトラムとを含む殺有害生物剤混合物 |
| ES2645751T3 (es) | 2008-09-12 | 2017-12-07 | Dow Agrosciences Llc | Composiciones plaguicidas estabilizadas |
| UA108200C2 (uk) * | 2009-05-08 | 2015-04-10 | Лікарські форми та способи застосування ектопаразитоцидів | |
| TWI510189B (zh) * | 2009-06-19 | 2015-12-01 | Lilly Co Eli | 殺外寄生蟲之方法及調配物 |
-
2010
- 2010-06-10 TW TW099118946A patent/TWI510189B/zh active
- 2010-06-16 CN CN201410269641.7A patent/CN104115831A/zh active Pending
- 2010-06-16 EP EP10727315.3A patent/EP2442646B1/en active Active
- 2010-06-16 WO PCT/US2010/038768 patent/WO2010148053A1/en not_active Ceased
- 2010-06-16 JP JP2012516226A patent/JP5738853B2/ja active Active
- 2010-06-16 PL PL10727315T patent/PL2442646T3/pl unknown
- 2010-06-16 NZ NZ596645A patent/NZ596645A/xx unknown
- 2010-06-16 PT PT107273153T patent/PT2442646T/pt unknown
- 2010-06-16 NZ NZ614975A patent/NZ614975A/en unknown
- 2010-06-16 CN CN201080026479.6A patent/CN102802414B/zh active Active
- 2010-06-16 CA CA2764401A patent/CA2764401C/en active Active
- 2010-06-16 US US12/816,400 patent/US8871727B2/en active Active
- 2010-06-16 ES ES10727315.3T patent/ES2658155T3/es active Active
- 2010-06-16 MX MX2011014028A patent/MX2011014028A/es active IP Right Grant
- 2010-06-16 AU AU2010260102A patent/AU2010260102B2/en active Active
-
2011
- 2011-11-17 IL IL216441A patent/IL216441A0/en unknown
-
2014
- 2014-10-28 US US14/525,939 patent/US20150045313A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5738853B2 (ja) | 2015-06-24 |
| CA2764401A1 (en) | 2010-12-23 |
| EP2442646B1 (en) | 2018-01-10 |
| PT2442646T (pt) | 2018-03-26 |
| EP2442646A1 (en) | 2012-04-25 |
| NZ614975A (en) | 2014-12-24 |
| JP2012530709A (ja) | 2012-12-06 |
| CA2764401C (en) | 2014-02-18 |
| AU2010260102B2 (en) | 2013-09-26 |
| PL2442646T3 (pl) | 2018-06-29 |
| WO2010148053A1 (en) | 2010-12-23 |
| TW201102000A (en) | 2011-01-16 |
| US8871727B2 (en) | 2014-10-28 |
| AU2010260102A1 (en) | 2011-12-08 |
| MX2011014028A (es) | 2012-02-21 |
| US20150045313A1 (en) | 2015-02-12 |
| CN104115831A (zh) | 2014-10-29 |
| NZ596645A (en) | 2013-09-27 |
| IL216441A0 (en) | 2012-02-29 |
| CN102802414A (zh) | 2012-11-28 |
| CN102802414B (zh) | 2014-07-23 |
| TWI510189B (zh) | 2015-12-01 |
| US20100324129A1 (en) | 2010-12-23 |
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