ES2650742T3 - Combinación farmacéutica que comprende un agente de silenciamiento de CIP2A para usar en el tratamiento de un trastorno hiperproliferativo, preferiblemente uno con la función p53 deteriorada - Google Patents

Combinación farmacéutica que comprende un agente de silenciamiento de CIP2A para usar en el tratamiento de un trastorno hiperproliferativo, preferiblemente uno con la función p53 deteriorada Download PDF

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ES2650742T3
ES2650742T3 ES12762321.3T ES12762321T ES2650742T3 ES 2650742 T3 ES2650742 T3 ES 2650742T3 ES 12762321 T ES12762321 T ES 12762321T ES 2650742 T3 ES2650742 T3 ES 2650742T3
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cip2a
cancer
group
sirna
cells
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Spanish (es)
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Jukka Westermarck
Anna Cvrljevic
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University of Turku
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University of Turku
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K33/243—Platinum; Compounds thereof
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    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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ES12762321.3T 2011-09-06 2012-09-06 Combinación farmacéutica que comprende un agente de silenciamiento de CIP2A para usar en el tratamiento de un trastorno hiperproliferativo, preferiblemente uno con la función p53 deteriorada Active ES2650742T3 (es)

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US201161531337P 2011-09-06 2011-09-06
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US201161531337P 2011-09-06
PCT/FI2012/050862 WO2013034806A1 (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function

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