ES2628334T3 - Proteína de pared celular CwpV (CD0514) como marcador de diagnóstico para el ribotipo 027 del Clostridium difficile - Google Patents

Proteína de pared celular CwpV (CD0514) como marcador de diagnóstico para el ribotipo 027 del Clostridium difficile Download PDF

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Publication number
ES2628334T3
ES2628334T3 ES13787811.2T ES13787811T ES2628334T3 ES 2628334 T3 ES2628334 T3 ES 2628334T3 ES 13787811 T ES13787811 T ES 13787811T ES 2628334 T3 ES2628334 T3 ES 2628334T3
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ES
Spain
Prior art keywords
cwpv
ribotype
difficile
patient
strains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13787811.2T
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English (en)
Spanish (es)
Inventor
Manli Y. DAVIS
Krista A. WILLIAMS
Jocelyn N. BROWNING
David M. Lyerly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Techlab Inc
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Techlab Inc
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Publication date
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Publication of ES2628334T3 publication Critical patent/ES2628334T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES13787811.2T 2012-05-11 2013-05-09 Proteína de pared celular CwpV (CD0514) como marcador de diagnóstico para el ribotipo 027 del Clostridium difficile Active ES2628334T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261645964P 2012-05-11 2012-05-11
US201261645964P 2012-05-11
US201313889670 2013-05-08
US13/889,670 US9133527B2 (en) 2012-05-11 2013-05-08 Cell wall protein CwpV (CD0514) as a diagnostic marker for Clostridium difficile ribotype 027
PCT/US2013/040399 WO2013170065A1 (en) 2012-05-11 2013-05-09 Cell wall protein cwpv (cd0514) as a diagnostic marker for clostridium difficile ribotype 027

Publications (1)

Publication Number Publication Date
ES2628334T3 true ES2628334T3 (es) 2017-08-02

Family

ID=49548891

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13787811.2T Active ES2628334T3 (es) 2012-05-11 2013-05-09 Proteína de pared celular CwpV (CD0514) como marcador de diagnóstico para el ribotipo 027 del Clostridium difficile

Country Status (8)

Country Link
US (1) US9133527B2 (enExample)
EP (1) EP2847590B1 (enExample)
JP (1) JP6165238B2 (enExample)
AU (1) AU2013259381B2 (enExample)
CA (1) CA2872482C (enExample)
ES (1) ES2628334T3 (enExample)
NZ (1) NZ702383A (enExample)
WO (1) WO2013170065A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI126289B (en) * 2014-12-19 2016-09-15 Mobidiag Ltd Method for detecting the presence of a hypervirulent strain of Clostridium difficile
CN106814189B (zh) * 2016-12-20 2018-10-26 成都金思唯生物技术有限公司 一种检测艰难梭菌的试剂盒及其用途
US20190211377A1 (en) * 2016-12-22 2019-07-11 Roche Molecular Systems, Inc. Cobra probes to detect a marker for epidemic ribotypes of clostridium difficile

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965375A (en) * 1997-04-04 1999-10-12 Biosite Diagnostics Diagnostic tests and kits for Clostridium difficile
ES2564169T3 (es) * 2004-11-24 2016-03-18 Techlab, Inc. Dispositivo y método para la detección de analitos
CA2714720A1 (en) * 2008-02-28 2009-09-03 3M Innovative Properties Company Antibodies to clostridium difficile spores and uses thereof
ATE478967T1 (de) * 2008-09-16 2010-09-15 Oesterreichische Agentur Fuer Pcr-ribotyping
US20120028819A1 (en) * 2009-04-07 2012-02-02 Koninklijke Philips Electronics N.V. Method for the detection and characterization of a toxinogenic clostridium difficile strain
US8889363B2 (en) 2009-07-27 2014-11-18 Biodics Method for the detection and identification of a variant C. difficile strain in a sample
JP5591332B2 (ja) * 2009-07-27 2014-09-17 バイオディクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 試料中における変異したｃ．ディフィシル菌株を検出および同定するための方法
US20120276060A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
US8790880B2 (en) 2011-09-26 2014-07-29 Techlab, Inc. Cysteine protease Cwp84 (CD2787) as a diagnostic marker for Clostridium difficile

Also Published As

Publication number Publication date
US9133527B2 (en) 2015-09-15
EP2847590B1 (en) 2017-04-05
CA2872482A1 (en) 2013-11-14
CA2872482C (en) 2017-10-31
WO2013170065A1 (en) 2013-11-14
JP6165238B2 (ja) 2017-07-19
NZ702383A (en) 2016-12-23
JP2015517658A (ja) 2015-06-22
US20130302813A1 (en) 2013-11-14
EP2847590A1 (en) 2015-03-18
AU2013259381A1 (en) 2014-12-04
AU2013259381B2 (en) 2018-08-16
EP2847590A4 (en) 2015-11-25

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