JP6165238B2 - クロストリジウム・ディフィシル（Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅ）・リボタイプ０２７の診断マーカーとしての細胞壁タンパク質ＣｗｐＶ（ＣＤ０５１４） - Google Patents

クロストリジウム・ディフィシル（Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅ）・リボタイプ０２７の診断マーカーとしての細胞壁タンパク質ＣｗｐＶ（ＣＤ０５１４） Download PDF

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JP6165238B2
JP6165238B2 JP2015511712A JP2015511712A JP6165238B2 JP 6165238 B2 JP6165238 B2 JP 6165238B2 JP 2015511712 A JP2015511712 A JP 2015511712A JP 2015511712 A JP2015511712 A JP 2015511712A JP 6165238 B2 JP6165238 B2 JP 6165238B2
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cwpv
difficile
ribotype
immunoassay
antibody
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JP2015517658A5 (enExample
JP2015517658A (ja
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デイビス，マンリ・ワイ
ウィリアムズ，クリスタ・エイ
ブラウニング，ジョスリン・エヌ
リヤリー，デヴィッド・エム
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テックラブ，インコーポレーテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2015511712A 2012-05-11 2013-05-09 クロストリジウム・ディフィシル（Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅ）・リボタイプ０２７の診断マーカーとしての細胞壁タンパク質ＣｗｐＶ（ＣＤ０５１４） Active JP6165238B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261645964P 2012-05-11 2012-05-11
US61/645,964 2012-05-11
US13/889,670 US9133527B2 (en) 2012-05-11 2013-05-08 Cell wall protein CwpV (CD0514) as a diagnostic marker for Clostridium difficile ribotype 027
US13/889,670 2013-05-08
PCT/US2013/040399 WO2013170065A1 (en) 2012-05-11 2013-05-09 Cell wall protein cwpv (cd0514) as a diagnostic marker for clostridium difficile ribotype 027

Publications (3)

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JP2015517658A JP2015517658A (ja) 2015-06-22
JP2015517658A5 JP2015517658A5 (enExample) 2015-09-24
JP6165238B2 true JP6165238B2 (ja) 2017-07-19

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JP2015511712A Active JP6165238B2 (ja) 2012-05-11 2013-05-09 クロストリジウム・ディフィシル（Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅ）・リボタイプ０２７の診断マーカーとしての細胞壁タンパク質ＣｗｐＶ（ＣＤ０５１４）

Country Status (8)

Country Link
US (1) US9133527B2 (enExample)
EP (1) EP2847590B1 (enExample)
JP (1) JP6165238B2 (enExample)
AU (1) AU2013259381B2 (enExample)
CA (1) CA2872482C (enExample)
ES (1) ES2628334T3 (enExample)
NZ (1) NZ702383A (enExample)
WO (1) WO2013170065A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI126289B (en) * 2014-12-19 2016-09-15 Mobidiag Ltd Method for detecting the presence of a hypervirulent strain of Clostridium difficile
CN106814189B (zh) * 2016-12-20 2018-10-26 成都金思唯生物技术有限公司 一种检测艰难梭菌的试剂盒及其用途
US20190211377A1 (en) * 2016-12-22 2019-07-11 Roche Molecular Systems, Inc. Cobra probes to detect a marker for epidemic ribotypes of clostridium difficile

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965375A (en) * 1997-04-04 1999-10-12 Biosite Diagnostics Diagnostic tests and kits for Clostridium difficile
ES2564169T3 (es) * 2004-11-24 2016-03-18 Techlab, Inc. Dispositivo y método para la detección de analitos
CA2714720A1 (en) * 2008-02-28 2009-09-03 3M Innovative Properties Company Antibodies to clostridium difficile spores and uses thereof
ATE478967T1 (de) * 2008-09-16 2010-09-15 Oesterreichische Agentur Fuer Pcr-ribotyping
US20120028819A1 (en) * 2009-04-07 2012-02-02 Koninklijke Philips Electronics N.V. Method for the detection and characterization of a toxinogenic clostridium difficile strain
US8889363B2 (en) 2009-07-27 2014-11-18 Biodics Method for the detection and identification of a variant C. difficile strain in a sample
JP5591332B2 (ja) * 2009-07-27 2014-09-17 バイオディクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 試料中における変異したｃ．ディフィシル菌株を検出および同定するための方法
US20120276060A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
US8790880B2 (en) 2011-09-26 2014-07-29 Techlab, Inc. Cysteine protease Cwp84 (CD2787) as a diagnostic marker for Clostridium difficile

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Publication number Publication date
US9133527B2 (en) 2015-09-15
EP2847590B1 (en) 2017-04-05
CA2872482A1 (en) 2013-11-14
CA2872482C (en) 2017-10-31
WO2013170065A1 (en) 2013-11-14
NZ702383A (en) 2016-12-23
JP2015517658A (ja) 2015-06-22
US20130302813A1 (en) 2013-11-14
EP2847590A1 (en) 2015-03-18
AU2013259381A1 (en) 2014-12-04
AU2013259381B2 (en) 2018-08-16
ES2628334T3 (es) 2017-08-02
EP2847590A4 (en) 2015-11-25

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