ES2599635T3 - Inmunoanálisis para la cuantificación de un antígeno inestable seleccionado de BNP y proBNP - Google Patents

Inmunoanálisis para la cuantificación de un antígeno inestable seleccionado de BNP y proBNP Download PDF

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Publication number
ES2599635T3
ES2599635T3 ES08736833.8T ES08736833T ES2599635T3 ES 2599635 T3 ES2599635 T3 ES 2599635T3 ES 08736833 T ES08736833 T ES 08736833T ES 2599635 T3 ES2599635 T3 ES 2599635T3
Authority
ES
Spain
Prior art keywords
bnp
probnp
order
antibody
immunocomplex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08736833.8T
Other languages
English (en)
Spanish (es)
Inventor
Natalia N. Tamm
Alexey G. Katrukha
Vladimir L. Filatov
Olga V. Kolosova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hytest Ltd
Original Assignee
Hytest Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hytest Ltd filed Critical Hytest Ltd
Application granted granted Critical
Publication of ES2599635T3 publication Critical patent/ES2599635T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES08736833.8T 2007-04-13 2008-04-14 Inmunoanálisis para la cuantificación de un antígeno inestable seleccionado de BNP y proBNP Active ES2599635T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US91160307P 2007-04-13 2007-04-13
US911603P 2007-04-13
FI20075251A FI20075251A0 (fi) 2007-04-13 2007-04-13 Immunomääritys epästabiilien antigeenien määrittämiseksi
FI20075251 2007-04-13
PCT/FI2008/050184 WO2008125733A1 (en) 2007-04-13 2008-04-14 Immunoassay for quantification of an unstable antigen selected from bnp and probnp

Publications (1)

Publication Number Publication Date
ES2599635T3 true ES2599635T3 (es) 2017-02-02

Family

ID=38009904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08736833.8T Active ES2599635T3 (es) 2007-04-13 2008-04-14 Inmunoanálisis para la cuantificación de un antígeno inestable seleccionado de BNP y proBNP

Country Status (9)

Country Link
US (3) US9034591B2 (https=)
EP (1) EP2135087B1 (https=)
JP (1) JP5686593B2 (https=)
CN (1) CN101842707B (https=)
CA (1) CA2683911C (https=)
DK (1) DK2135087T3 (https=)
ES (1) ES2599635T3 (https=)
FI (1) FI20075251A0 (https=)
WO (1) WO2008125733A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2919611B1 (fr) 2007-08-03 2009-10-23 Bio Rad Pasteur Sa Nouvel epitope du bnp (1-32) et anticorps diriges contre cet epitope
US8778699B2 (en) 2010-08-04 2014-07-15 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
JP2012140331A (ja) * 2010-12-28 2012-07-26 Tosoh Corp タグペプチド
EP2712423A4 (en) 2011-02-25 2015-06-10 Wellstat Diagnostics Llc Assays for detecting enzymatic activity
AU2012262154B2 (en) 2011-05-31 2016-08-04 Idexx Laboratories, Inc. Detection of degradation products of feline NT-proBNP
EP2759551B1 (en) * 2011-09-21 2019-05-22 Fujirebio Inc. Antibodies binding to an affinity complex comprising 25oh vitamin d2 or d3 and an antibody thereto
CN102608335A (zh) * 2012-04-19 2012-07-25 协和生物制药（天津）有限公司 NT-proBNP时间分辨荧光免疫分析试剂盒的制备方法
JP7664226B2 (ja) 2019-08-13 2025-04-17 ゲンティアン アクティーゼルスカブ Ｎｔ－プロｂｎｐの定量のための高感度粒子増感アッセイ
CN113956355B (zh) * 2021-07-26 2023-06-23 无锡傲锐东源生物科技有限公司 抗人脑利钠肽(bnp)兔单克隆抗体及其应用
IL311792A (en) 2021-10-01 2024-05-01 Gentian As A new method for determining the concentration of N-terminal prohormone BNP (NT-PROBNP) in a sample

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
CN1161609C (zh) * 1997-09-11 2004-08-11 盐野义制药株式会社 哺乳类γ－BNP衍生物特异的免疫测定方法及其试剂盒
US20030219734A1 (en) 2001-04-13 2003-11-27 Biosite Incorporated Polypeptides related to natriuretic peptides and methods of their identification and use
CA2430889A1 (en) * 2002-06-19 2003-12-19 Bayer Corporation Stabilization of brain natriuretic peptide (bnp) in blood samples, methods and compositions related thereto
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
KR100771999B1 (ko) * 2004-05-20 2007-10-31 김상돈 그레이팅
US7731965B2 (en) * 2005-02-17 2010-06-08 Abbott Lab Human ring specific BNP antibodies
CA2629438C (en) 2005-11-09 2014-02-25 Abbott Laboratories Human bnp immunospecific antibodies
WO2007138163A2 (en) * 2006-05-26 2007-12-06 Hytest Ltd. Antibodies and standard for nt-probnp and probnp immunoassays
US20080064045A1 (en) 2006-09-07 2008-03-13 Huaiqin Wu Biomarker fragments for the detection of human BNP

Also Published As

Publication number Publication date
CN101842707B (zh) 2016-11-09
FI20075251A0 (fi) 2007-04-13
EP2135087A4 (en) 2011-06-22
US20130071949A1 (en) 2013-03-21
US9034592B2 (en) 2015-05-19
US9034591B2 (en) 2015-05-19
EP2135087A1 (en) 2009-12-23
CA2683911A1 (en) 2008-10-23
DK2135087T3 (en) 2016-11-14
US20150219675A1 (en) 2015-08-06
WO2008125733A1 (en) 2008-10-23
EP2135087B1 (en) 2016-09-14
JP5686593B2 (ja) 2015-03-18
CN101842707A (zh) 2010-09-22
US9145459B2 (en) 2015-09-29
WO2008125733A8 (en) 2009-07-30
JP2010523994A (ja) 2010-07-15
CA2683911C (en) 2017-01-10
US20100203560A1 (en) 2010-08-12

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