ES2566907T3 - Revestimiento que comprende un terpolímero que comprende caprolactona y glicolida - Google Patents

Revestimiento que comprende un terpolímero que comprende caprolactona y glicolida Download PDF

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Publication number
ES2566907T3
ES2566907T3 ES10718390.7T ES10718390T ES2566907T3 ES 2566907 T3 ES2566907 T3 ES 2566907T3 ES 10718390 T ES10718390 T ES 10718390T ES 2566907 T3 ES2566907 T3 ES 2566907T3
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ES
Spain
Prior art keywords
glycolide
amorphous
molar
poly
caprolactone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10718390.7T
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English (en)
Inventor
Florencia Lim
Michael Ngo
Syed Faiyaz Ahmed Hossainy
Mikael Trollsas
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Abbott Cardiovascular Systems Inc
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Abbott Cardiovascular Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Abbott Cardiovascular Systems Inc filed Critical Abbott Cardiovascular Systems Inc
Application granted granted Critical
Publication of ES2566907T3 publication Critical patent/ES2566907T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation

Abstract

Un dispositivo implantable, que comprende un revestimiento que comprende una capa de reservorio que comprende un terpolímero que comprende caprolactona, glicolida y un tercer monómero, teniendo el terpolímero una composición molar en la que la caprolactona supone un 20 % o superior y la glicolida supone un 10 % o superior, en el que el revestimiento tiene un grosor de 5 micras o menos y una velocidad de degradación o absorción tal que, en un periodo de 6 meses después del despliegue del dispositivo implantable, el revestimiento tiene una pérdida de masa de 80 % o más, en el que el revestimiento comprende además una capa de imprimación que comprende un polímero amorfo biodegradable, en el que el polímero amorfo se selecciona del grupo consistente en poli(D,L-lactida) (PDLLA) amorfa, poli(Llactida- co-D,L-lactida) (PLLA-DLLA) amorfa con un contenido de D,L-Iactida de 30 % molar o superior, poli(D,Llactida- co-glicolida) (PDLLA-GA) amorfa con un contenido glicolida de 10 % a 50 % molar, poli(L-lactida-coglicolida) (PLLA-GA) amorfa con un contenido de L-Iactida de 70 % molar o inferior, poli(glicolida-co caprolactona) (PGA-CL) amorfa con un contenido de glicolida de 70 % molar o inferior, poli(D,L-lactida-cocaprolactona) (PDLLA-CL) amorfa con un contenido de caprolactona de 70 % molar o inferior y poli(L-lactida-cocaprolactona) (PLLA-CL) amorfa con un contenido de L-lactida inferior a 70 % molar, pero superior a 30 % molar; en el que la capa de imprimación no contiene el terpolímero que comprende caprolactona, glicolida y un tercer monómero.

Description

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Claims (1)

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ES10718390.7T 2009-05-14 2010-05-05 Revestimiento que comprende un terpolímero que comprende caprolactona y glicolida Active ES2566907T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/466,317 US8697113B2 (en) 2008-05-21 2009-05-14 Coating comprising a terpolymer comprising caprolactone and glycolide
US466317 2009-05-14
PCT/US2010/033787 WO2010132258A2 (en) 2009-05-14 2010-05-05 Coating comprising a terpolymer comprising caprolactone and glycolide

Publications (1)

Publication Number Publication Date
ES2566907T3 true ES2566907T3 (es) 2016-04-18

Family

ID=42232774

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10718390.7T Active ES2566907T3 (es) 2009-05-14 2010-05-05 Revestimiento que comprende un terpolímero que comprende caprolactona y glicolida

Country Status (6)

Country Link
US (2) US8697113B2 (es)
EP (2) EP2429602B1 (es)
JP (2) JP5804604B2 (es)
ES (1) ES2566907T3 (es)
HK (1) HK1215798A1 (es)
WO (1) WO2010132258A2 (es)

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US8661630B2 (en) 2008-05-21 2014-03-04 Abbott Cardiovascular Systems Inc. Coating comprising an amorphous primer layer and a semi-crystalline reservoir layer
US8697113B2 (en) * 2008-05-21 2014-04-15 Abbott Cardiovascular Systems Inc. Coating comprising a terpolymer comprising caprolactone and glycolide
US8697110B2 (en) * 2009-05-14 2014-04-15 Abbott Cardiovascular Systems Inc. Polymers comprising amorphous terpolymers and semicrystalline blocks
US9993441B2 (en) * 2009-12-30 2018-06-12 Surmodics, Inc. Controlled release matrix barrier structure for subcutaneous medical devices
US20150305899A1 (en) * 2014-04-24 2015-10-29 Abbott Cardiovascular Systems Inc. Branched polyhydroxyalkanoate systems for bioresorbable vascular scaffold applications
SG11201809800TA (en) 2016-05-06 2018-12-28 Saudi Arabian Oil Co Succinimide-based copolymers and use as hydrate inhibitors
JP6824562B2 (ja) 2016-05-06 2021-02-03 サウジ アラビアン オイル カンパニーＳａｕｄｉ Ａｒａｂｉａｎ Ｏｉｌ Ｃｏｍｐａｎｙ アクリルアミドベースのコポリマー、ターポリマー、および水化物阻害剤としての使用
US20170320985A1 (en) 2016-05-06 2017-11-09 Saudi Arabian Oil Company Methods for synthesizing acryloyl-based copolymers, terpolymers

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US8697113B2 (en) 2014-04-15
WO2010132258A3 (en) 2011-04-07
EP2429602B1 (en) 2016-01-06
JP2012526612A (ja) 2012-11-01
EP2429602A2 (en) 2012-03-21
HK1215798A1 (zh) 2016-09-15
US20100209476A1 (en) 2010-08-19
US20140107592A1 (en) 2014-04-17
WO2010132258A2 (en) 2010-11-18
EP2932988A1 (en) 2015-10-21
JP5804604B2 (ja) 2015-11-04

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