ES2564803T3 - Compuestos neuroprotectores bicíclicos y composiciones farmacéuticas que los contienen - Google Patents
Compuestos neuroprotectores bicíclicos y composiciones farmacéuticas que los contienen Download PDFInfo
- Publication number
- ES2564803T3 ES2564803T3 ES04782733.2T ES04782733T ES2564803T3 ES 2564803 T3 ES2564803 T3 ES 2564803T3 ES 04782733 T ES04782733 T ES 04782733T ES 2564803 T3 ES2564803 T3 ES 2564803T3
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- Prior art keywords
- substituted
- alkynyl
- alkenyl
- aryl
- heteroalkyl
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Landscapes
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
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| US49995603P | 2003-09-03 | 2003-09-03 | |
| US499956P | 2003-09-03 | ||
| PCT/US2004/028308 WO2005023815A2 (en) | 2003-09-03 | 2004-08-31 | Neuroprotective bicyclic compounds and methods for their use |
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| ES2564803T3 true ES2564803T3 (es) | 2016-03-29 |
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|---|---|
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| EP (1) | EP1664050B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4842817B2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1664050T3 (cg-RX-API-DMAC7.html) |
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| PL (1) | PL1664050T3 (cg-RX-API-DMAC7.html) |
| SI (1) | SI1664050T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005023815A2 (cg-RX-API-DMAC7.html) |
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| ES2381775T3 (es) | 2000-08-04 | 2012-05-31 | Dmi Biosciences, Inc. | Procedimiento del uso de dicetopiperazinas y composición que las contiene |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
| CN101947306B (zh) | 2003-05-15 | 2014-06-18 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
| WO2008063311A2 (en) * | 2006-10-11 | 2008-05-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| US8791117B2 (en) | 2003-09-03 | 2014-07-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| US8519127B2 (en) * | 2003-09-03 | 2013-08-27 | Mike John Bickerdike | Cyclic glycyl-2-allyl proline and its use in treatment of peripheral neuropathy |
| JP5856843B2 (ja) * | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| US9891219B2 (en) * | 2008-10-10 | 2018-02-13 | Mayo Foundation For Medical Education And Research | Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive |
| US7928233B2 (en) * | 2009-02-10 | 2011-04-19 | Hoffmann-La Roche Inc. | Spiroindolinone pyridine derivatives |
| US8507496B2 (en) | 2010-09-07 | 2013-08-13 | Dmi Acquisition Corp. | Treatment of diseases |
| KR102032400B1 (ko) | 2011-10-10 | 2019-10-15 | 앰피오 파마슈티컬스 인코퍼레이티드 | 퇴행성 관절 질환의 치료 |
| EP2765968A4 (en) | 2011-10-10 | 2015-01-21 | Ampio Pharmaceuticals Inc | IMPLANTABLE MEDICINE PRODUCTS WITH INCREASED IMMUNO TOLERANCE AND PROCESSING AND IMPLANTATION METHODS |
| SG10201605205VA (en) | 2011-10-28 | 2016-08-30 | Ampio Pharmaceuticals Inc | Treatment of rhinitis |
| CA2900335C (en) * | 2012-10-22 | 2021-10-26 | City Of Hope | Synthetic analogs of epipolythiodioxopiperazines and uses thereof |
| KR20150132508A (ko) | 2013-03-15 | 2015-11-25 | 앰피오 파마슈티컬스 인코퍼레이티드 | 줄기세포의 가동화, 회귀, 증식 및 분화를 위한 조성물 및 이의 사용 방법 |
| LT3024463T (lt) * | 2013-07-25 | 2020-07-10 | Neuren Pharmaceuticals Limited | Neuroapsauginiai bicikliniai junginiai ir jų panaudojimo būdai autizmo spektro sutrikimų ir neuroliginių vystymosi sutrikimų gydymui |
| EP4066836A1 (en) | 2014-08-18 | 2022-10-05 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| EP3310375A4 (en) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES |
| CN109562110A (zh) | 2016-05-26 | 2019-04-02 | 株式会社日本阿明诺化学 | 睡眠改善剂 |
| CN109952104B (zh) | 2016-09-15 | 2023-03-28 | 希望之城 | 二硫etp衍生物 |
| WO2019177142A1 (ja) | 2018-03-16 | 2019-09-19 | 脳科学香料株式会社 | 低酸素障害、虚血再灌流障害又は炎症の予防又は治療剤、移植用細胞保護剤、及び生体保存剤 |
| AU2019271189A1 (en) | 2018-05-15 | 2021-01-07 | Lloyd Hung Loi TRAN | Therapeutic agent composition and method of use, for treatment of mild cognitive impairment, depression, and psychological disorders |
| JP2022553060A (ja) | 2019-10-22 | 2022-12-21 | ニューレン ファーマシューティカルズ リミテッド | 二環式化合物及びピット・ホプキンス症候群の処置におけるそれらの使用方法 |
| US20240132511A1 (en) * | 2021-02-12 | 2024-04-25 | Neuren Pharmaceuticals Limited | Treatments of prader-willi syndrome |
| WO2025088052A1 (en) * | 2023-10-26 | 2025-05-01 | Rousselot Bv | Cyclic analogue of glycine-proline for use in the prevention and/or treatment of medical implant-related fibrosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH469006A (de) * | 1965-07-07 | 1969-02-28 | Sandoz Ag | Verfahren zur Herstellung neuer synthetischer Alkaloide |
| FI941826A7 (fi) * | 1993-04-21 | 1994-10-22 | Takeda Chemical Industries Ltd | Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi |
| US7202279B1 (en) * | 1998-02-11 | 2007-04-10 | Georgetown University | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders |
| WO2003039487A2 (en) * | 2001-11-09 | 2003-05-15 | Neuronz Limited | Cyclo(prolyl-glycine) and methods of use to treat neural disorders |
| CA2466701C (en) | 2001-11-13 | 2013-11-12 | Loi Tran | Neuroprotective use of cyclic prolyl glycine |
| US7232798B2 (en) * | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
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2004
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- 2004-08-31 EP EP04782733.2A patent/EP1664050B1/en not_active Expired - Lifetime
- 2004-08-31 SI SI200432303T patent/SI1664050T1/sl unknown
- 2004-08-31 JP JP2006525396A patent/JP4842817B2/ja not_active Expired - Lifetime
- 2004-08-31 DK DK04782733.2T patent/DK1664050T3/en active
- 2004-08-31 HU HUE04782733A patent/HUE028528T2/en unknown
- 2004-08-31 PL PL04782733T patent/PL1664050T3/pl unknown
- 2004-08-31 US US10/570,395 patent/US8067425B2/en not_active Expired - Lifetime
- 2004-08-31 ES ES04782733.2T patent/ES2564803T3/es not_active Expired - Lifetime
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2006
- 2006-04-07 US US11/399,974 patent/US7776876B2/en active Active
Also Published As
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| US20060258663A1 (en) | 2006-11-16 |
| SI1664050T1 (sl) | 2016-04-29 |
| WO2005023815A2 (en) | 2005-03-17 |
| PL1664050T3 (pl) | 2016-08-31 |
| US20070197511A1 (en) | 2007-08-23 |
| JP2007504235A (ja) | 2007-03-01 |
| HUE028528T2 (en) | 2016-12-28 |
| EP1664050A2 (en) | 2006-06-07 |
| US8067425B2 (en) | 2011-11-29 |
| DK1664050T3 (en) | 2016-03-07 |
| JP4842817B2 (ja) | 2011-12-21 |
| EP1664050B1 (en) | 2015-12-09 |
| WO2005023815A3 (en) | 2005-07-21 |
| US7776876B2 (en) | 2010-08-17 |
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