ES2564026T3 - Antígenos de micobacterias - Google Patents

Antígenos de micobacterias Download PDF

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Publication number
ES2564026T3
ES2564026T3 ES13182794.1T ES13182794T ES2564026T3 ES 2564026 T3 ES2564026 T3 ES 2564026T3 ES 13182794 T ES13182794 T ES 13182794T ES 2564026 T3 ES2564026 T3 ES 2564026T3
Authority
ES
Spain
Prior art keywords
seq
mycobacterial antigens
imc
mammal
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13182794.1T
Other languages
English (en)
Inventor
Hans Martin Vordermeier
Benjamin Sidders
Neil Graham Stoker
Katie Ewer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Environment Food and Rural Affairs
Original Assignee
UK Secretary of State for Environment Food and Rural Affairs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UK Secretary of State for Environment Food and Rural Affairs filed Critical UK Secretary of State for Environment Food and Rural Affairs
Application granted granted Critical
Publication of ES2564026T3 publication Critical patent/ES2564026T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un reactivo de diagnóstico de ensayo de inmunidad mediada por célula (CMI) para uso en la detección de infección por M. tuberculosis en un mamífero, que comprende uno o más péptidos consistente cada uno en una de las SEQ ID NO: 2-13, o una variante funcional que tiene al menos un 90% de identidad de secuencia con y es capaz de desencadenar una respuesta inmunitaria similar a la SEQ ID NO: 2-13.

Description

13
ES13182794.1T 2007-11-10 2008-11-06 Antígenos de micobacterias Active ES2564026T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0722105.4A GB0722105D0 (en) 2007-11-10 2007-11-10 Antigens
GB0722105 2007-11-10

Publications (1)

Publication Number Publication Date
ES2564026T3 true ES2564026T3 (es) 2016-03-17

Family

ID=38858506

Family Applications (3)

Application Number Title Priority Date Filing Date
ES14188545.9T Active ES2618336T3 (es) 2007-11-10 2008-11-06 Antígenos de micobacterias
ES08848298T Active ES2431891T3 (es) 2007-11-10 2008-11-06 Antígenos de micobacterias
ES13182794.1T Active ES2564026T3 (es) 2007-11-10 2008-11-06 Antígenos de micobacterias

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES14188545.9T Active ES2618336T3 (es) 2007-11-10 2008-11-06 Antígenos de micobacterias
ES08848298T Active ES2431891T3 (es) 2007-11-10 2008-11-06 Antígenos de micobacterias

Country Status (12)

Country Link
US (5) US8697091B2 (es)
EP (3) EP2827149B1 (es)
AU (2) AU2008324031B2 (es)
CA (1) CA2703395C (es)
DK (3) DK2827149T3 (es)
ES (3) ES2618336T3 (es)
GB (1) GB0722105D0 (es)
HR (1) HRP20131015T1 (es)
NZ (1) NZ584481A (es)
PL (1) PL2210105T3 (es)
PT (1) PT2210105E (es)
WO (1) WO2009060184A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29858A (id) * 1998-11-04 2001-10-18 Isis Innovation Uji diagnostik tuberkulosis
GB0618127D0 (en) * 2006-09-14 2006-10-25 Isis Innovation Biomarker
GB0722105D0 (en) * 2007-11-10 2007-12-19 Sec Dep For Environment Food A Antigens
GB0906215D0 (en) * 2009-04-09 2009-05-20 Lalvani Ajit Diagnostic test
GB201007075D0 (en) 2010-04-28 2010-06-09 Sec Dep For Environment Food A Diagnostic reagents
GB201012072D0 (en) 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
ITRM20100411A1 (it) * 2010-07-23 2012-01-24 Massimo Amicosante Uso di sequenze amminoacidiche da mycobacterium tuberculosis o dei loro corrispondenti acidi nucleici per la diagnosi e la prevenzione di infezione tubercolare, relativo kit diagnostico e vaccino.
CN103257236B (zh) * 2012-02-20 2015-04-15 南京市疾病预防控制中心 Hla-a24限制性结核分支杆菌特异性ctl细胞表位肽的应用
BR112015000530A2 (pt) * 2012-07-10 2018-08-28 Transgene Sa vacina de antígeno micobacteriano.
WO2018111536A1 (en) 2016-12-14 2018-06-21 Becton, Dickinson And Company Methods and compositions for obtaining a tuberculosis assessment in a subject
GB201909953D0 (en) 2019-07-11 2019-08-28 Sec Dep For Environment Food And Rural Affairs Acting Through The Animal And Plant Health Agency Diagnostic reagents
KR20230080458A (ko) 2020-10-06 2023-06-07 세페이드 결핵을 진단하고 활동성 및 잠복 결핵을 구별하는 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10034826A1 (de) 2000-07-18 2002-01-31 Bosch Gmbh Robert Baugruppe mit einem strukturierten Tärgerelement und einem mit diesem wirkverbundenen Substrat
AU2002302919A1 (en) 2001-02-22 2002-10-03 Institut Pasteur Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
WO2003027150A1 (fr) * 2001-09-26 2003-04-03 Takeda Chemical Industries, Ltd. Anticorps et son utilisation
EP1578432A4 (en) * 2002-10-03 2008-07-30 Epimmune Inc HLA BINDING PEPTIDES AND USES THEREOF
NZ560412A (en) * 2005-01-20 2009-06-26 Biomarck Pharmaceuticals Ltd Mucin hypersecretion inhibitors based on the structure of MANS and methods of use
WO2008028489A2 (en) 2006-09-05 2008-03-13 Hvidovre Hospital Ip-i0 based immunological monitoring
GB0716070D0 (en) 2007-08-17 2007-09-26 Fusion Antibodies Ltd Diagnostic method and kit
GB0722105D0 (en) * 2007-11-10 2007-12-19 Sec Dep For Environment Food A Antigens
GB0906215D0 (en) 2009-04-09 2009-05-20 Lalvani Ajit Diagnostic test

Also Published As

Publication number Publication date
GB0722105D0 (en) 2007-12-19
EP2210105B1 (en) 2013-09-04
US20100317036A1 (en) 2010-12-16
US20190170746A1 (en) 2019-06-06
EP2672268B1 (en) 2016-02-10
EP2827149A1 (en) 2015-01-21
US9618509B2 (en) 2017-04-11
US20140296091A1 (en) 2014-10-02
DK2210105T3 (da) 2013-11-04
PL2210105T3 (pl) 2014-01-31
AU2008324031B2 (en) 2013-06-27
US9285364B2 (en) 2016-03-15
AU2010100407A4 (en) 2010-05-27
AU2008324031A1 (en) 2009-05-14
US10578617B2 (en) 2020-03-03
US20170269079A1 (en) 2017-09-21
PT2210105E (pt) 2013-10-30
CA2703395C (en) 2018-09-25
ES2431891T3 (es) 2013-11-28
US20160153987A1 (en) 2016-06-02
EP2210105A1 (en) 2010-07-28
ES2618336T3 (es) 2017-06-21
NZ584481A (en) 2011-12-22
DK2827149T3 (en) 2017-02-06
HRP20131015T1 (hr) 2013-12-20
CA2703395A1 (en) 2009-05-14
WO2009060184A1 (en) 2009-05-14
EP2827149B1 (en) 2017-01-04
EP2672268A1 (en) 2013-12-11
DK2672268T3 (en) 2016-03-29
US8697091B2 (en) 2014-04-15

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