ES2555864T3 - Ensayo para la medición de anticuerpos de unión a un anticuerpo monoclonal terapéutico - Google Patents

Ensayo para la medición de anticuerpos de unión a un anticuerpo monoclonal terapéutico Download PDF

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Publication number
ES2555864T3
ES2555864T3 ES11746230.9T ES11746230T ES2555864T3 ES 2555864 T3 ES2555864 T3 ES 2555864T3 ES 11746230 T ES11746230 T ES 11746230T ES 2555864 T3 ES2555864 T3 ES 2555864T3
Authority
ES
Spain
Prior art keywords
acmt
antibody
monoclonal antibody
sample
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11746230.9T
Other languages
English (en)
Spanish (es)
Inventor
Veit Peter Grunert
Ursula Klause
Pavel Kubalec
Matthias Rothfuss
Barbara Upmeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2555864T3 publication Critical patent/ES2555864T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES11746230.9T 2010-08-19 2011-08-17 Ensayo para la medición de anticuerpos de unión a un anticuerpo monoclonal terapéutico Active ES2555864T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10173408 2010-08-19
EP10173408 2010-08-19
PCT/EP2011/064178 WO2012022774A1 (en) 2010-08-19 2011-08-17 An assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Publications (1)

Publication Number Publication Date
ES2555864T3 true ES2555864T3 (es) 2016-01-11

Family

ID=42727619

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11746230.9T Active ES2555864T3 (es) 2010-08-19 2011-08-17 Ensayo para la medición de anticuerpos de unión a un anticuerpo monoclonal terapéutico

Country Status (7)

Country Link
US (1) US9081016B2 (cg-RX-API-DMAC7.html)
EP (1) EP2606362B1 (cg-RX-API-DMAC7.html)
JP (1) JP5805190B2 (cg-RX-API-DMAC7.html)
CN (1) CN103109190B (cg-RX-API-DMAC7.html)
CA (1) CA2802278A1 (cg-RX-API-DMAC7.html)
ES (1) ES2555864T3 (cg-RX-API-DMAC7.html)
WO (1) WO2012022774A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

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CN104614535B (zh) * 2015-02-10 2017-11-28 深圳市新产业生物医学工程股份有限公司 甲状腺微粒体抗体检测试剂盒及其制备方法和应用
US11119096B2 (en) * 2016-07-08 2021-09-14 W. Health L.P. Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
CN106093413A (zh) * 2016-07-18 2016-11-09 本·沙朗 一种抗英夫利西抗体elisa检测试剂盒和检测方法
CA3075900A1 (en) * 2017-09-15 2019-03-21 Beckman Coulter, Inc. Flow based assays for therapeutics
US20190302124A1 (en) * 2018-03-27 2019-10-03 Laboratory Corporation Of America Holdings Compositions and Methods for Identifying Subjects Who May Benefit From Treatment With Therapeutic Agents
JP7570421B2 (ja) * 2020-01-02 2024-10-21 エフ． ホフマン－ラ ロシュ アーゲー Ａｄａ応答特定アッセイ
CN115552244A (zh) * 2020-05-08 2022-12-30 豪夫迈·罗氏有限公司 用于高药物耐受性测试的高离子强度解离测定
CN117590002B (zh) * 2023-11-23 2024-10-22 上海领检科技有限公司 一种TNFα抗药抗体的检测方法及检测试剂盒

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Also Published As

Publication number Publication date
CA2802278A1 (en) 2012-02-23
JP2013536419A (ja) 2013-09-19
CN103109190A (zh) 2013-05-15
JP5805190B2 (ja) 2015-11-04
CN103109190B (zh) 2015-07-22
EP2606362B1 (en) 2015-09-30
US20130157892A1 (en) 2013-06-20
US9081016B2 (en) 2015-07-14
WO2012022774A1 (en) 2012-02-23
EP2606362A1 (en) 2013-06-26
HK1180767A1 (en) 2013-10-25

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