ES2551880T3 - Un proceso para la preparación de ácido N,N'-bis(2-hidroxibencil)etilenodiamino-N,N'-diacético y sus derivados - Google Patents

Un proceso para la preparación de ácido N,N'-bis(2-hidroxibencil)etilenodiamino-N,N'-diacético y sus derivados Download PDF

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Publication number
ES2551880T3
ES2551880T3 ES07465006.0T ES07465006T ES2551880T3 ES 2551880 T3 ES2551880 T3 ES 2551880T3 ES 07465006 T ES07465006 T ES 07465006T ES 2551880 T3 ES2551880 T3 ES 2551880T3
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ES
Spain
Prior art keywords
formula
compound
ethylenediamine
reaction
alkanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07465006.0T
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English (en)
Spanish (es)
Inventor
Adam Nawrocki
Radoslaw Olszewski
Filip Stefaniak
Anika Mrozek-Niecko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PRZED PROD CONSULTINGOWE ADOB SP Z O O SP K
Przedsiebiorstwo Produkcyjno-Consultingowe Adob Sp Z Oo Sp K
Original Assignee
PRZED PROD CONSULTINGOWE ADOB SP Z O O SP K
Przedsiebiorstwo Produkcyjno-Consultingowe Adob Sp Z Oo Sp K
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Application granted granted Critical
Publication of ES2551880T3 publication Critical patent/ES2551880T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES07465006.0T 2007-09-20 2007-09-20 Un proceso para la preparación de ácido N,N'-bis(2-hidroxibencil)etilenodiamino-N,N'-diacético y sus derivados Active ES2551880T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07465006.0A EP2039679B1 (en) 2007-09-20 2007-09-20 A process for the preparation of N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid and its derivatives

Publications (1)

Publication Number Publication Date
ES2551880T3 true ES2551880T3 (es) 2015-11-24

Family

ID=39665857

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07465006.0T Active ES2551880T3 (es) 2007-09-20 2007-09-20 Un proceso para la preparación de ácido N,N'-bis(2-hidroxibencil)etilenodiamino-N,N'-diacético y sus derivados

Country Status (8)

Country Link
US (1) US8431734B2 (enExample)
EP (1) EP2039679B1 (enExample)
JP (1) JP5289447B2 (enExample)
CN (1) CN101784518B (enExample)
DK (1) DK2039679T3 (enExample)
ES (1) ES2551880T3 (enExample)
PL (1) PL2039679T3 (enExample)
WO (1) WO2009037235A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2389579T3 (es) 2009-07-17 2012-10-29 Przedsiebiorstwo Produkcyjno-Consultingowe Adob Sp. Z O.O. Sp.K. Un procedimiento para la preparación de quelatos de Fe(III) de ácido N,N'-di(2-hidroxibencil)-etilendiamino-N,N'-diacético y sus derivados
US8378134B2 (en) 2009-09-30 2013-02-19 General Electric Company Hydroxylated contrast enhancement agents
US20110077396A1 (en) * 2009-09-30 2011-03-31 General Electric Company Intermediates for hydroxylated contrast enhancement agents
ES2733466T3 (es) 2015-06-25 2019-11-29 Nouryon Chemicals Int Bv Proceso para preparar compuestos fenólicos del ácido etilendiaminodiacético
CN107709287B (zh) * 2015-06-25 2020-07-17 阿克苏诺贝尔化学品国际有限公司 制备酚乙二胺二乙酸化合物的方法
WO2017004052A2 (en) * 2015-06-29 2017-01-05 Spero Energy, Inc. Compounds and compositions for delivery of nutrients and micronutrients to plants
CN108568316B (zh) * 2018-04-27 2021-03-30 华南理工大学 一类高稳定锆基手性催化剂及制备方法与其应用
CN112390733A (zh) * 2020-10-16 2021-02-23 中国辐射防护研究院 一种新型螯合剂及其制备方法
CN112358422B (zh) * 2020-10-16 2023-06-23 中国辐射防护研究院 一种新型螯合剂nbed的制备方法
KR102888292B1 (ko) 2020-10-30 2025-11-19 주식회사 엘지화학 술포닐플루오라이드기 함유 화합물 및 이의 제조방법
EP3848349B1 (en) 2020-12-01 2023-03-15 Przedsiebiorstwo Produkcyjno-Consultingowe ADOB Sp. z o.o. A process for the preparation of salts of n,n'-disubstituted ethylenediamine-n,n'-diacetic acid derivatives and their use
WO2022235768A1 (en) 2021-05-04 2022-11-10 Sachem, Inc. Strong binding metal-chelating resins
US12331155B2 (en) 2021-05-04 2025-06-17 Sachem, Inc. Strong binding metal-chelating resins using macrocycle molecules

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US3038793A (en) * 1955-12-06 1962-06-12 Geigy Chem Corp Treating iron deficient plants with ferric chelates of ethylenediaminediacetic acids containing phenolic groups
US2967196A (en) * 1955-12-06 1961-01-03 Geigy Chem Corp Ethylenediaminediacetic acids containing phenolic groups
US3632637A (en) * 1968-02-13 1972-01-04 Arthur E Martell Hydroxyaryl-containing aminocarboxylic chelating agents
US4073804A (en) * 1976-05-04 1978-02-14 Boise Cascade Corporation Producing glycine by the reductive amination of glyoxylic acid
CH602857A5 (enExample) * 1976-12-10 1978-08-15 Ciba Geigy Ag
US4130582A (en) * 1977-04-19 1978-12-19 Ciba-Geigy Corporation Preparation of phenolic ethylenediaminepolycarboxylic acids
HUT41715A (en) * 1984-12-28 1987-05-28 Monsanto Co Process for preparing n-substituted alpha-aminoacids and derivatives thereof
FR2627772B1 (fr) * 1988-02-29 1990-08-17 Protex Manuf Prod Chimiq Nouveau procede de preparation de l'acide ethylene-diamine-n-n(prime)-bis(ortho-hydroxyphenylacetique) et de derives de celui-ci
IE980696A1 (en) * 1988-10-31 2000-12-13 Dow Chemical Co Chelants processing ortho ligating functionality and complexes thereof
DE4408530A1 (de) * 1994-03-14 1995-09-28 Hoechst Ag Verfahren zur Herstellung von Aminoethylglycin
US7405320B2 (en) * 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
AU2456201A (en) * 1999-12-21 2001-07-03 University Of Florida Research Foundation, Inc. N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy
CA2522323C (en) * 2003-04-14 2009-09-15 Pfizer Products Inc. 3-azabicyclo[3.2.1]octane derivatives as opioid receptor ligands
US7884059B2 (en) * 2004-10-20 2011-02-08 Afton Chemical Corporation Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted Mannich bases

Also Published As

Publication number Publication date
CN101784518B (zh) 2013-11-13
WO2009037235A1 (en) 2009-03-26
JP5289447B2 (ja) 2013-09-11
PL2039679T3 (pl) 2015-10-30
HK1146403A1 (en) 2011-06-03
DK2039679T3 (en) 2015-11-02
US20100168469A1 (en) 2010-07-01
EP2039679B1 (en) 2015-08-12
JP2010539212A (ja) 2010-12-16
EP2039679A1 (en) 2009-03-25
US8431734B2 (en) 2013-04-30
CN101784518A (zh) 2010-07-21

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