ES254043A1 - 3-substituted azetidines - Google Patents

3-substituted azetidines

Info

Publication number
ES254043A1
ES254043A1 ES0254043A ES254043A ES254043A1 ES 254043 A1 ES254043 A1 ES 254043A1 ES 0254043 A ES0254043 A ES 0254043A ES 254043 A ES254043 A ES 254043A ES 254043 A1 ES254043 A1 ES 254043A1
Authority
ES
Spain
Prior art keywords
phenyl
alkyl
cycloalkyl
general formula
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0254043A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Publication of ES254043A1 publication Critical patent/ES254043A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0872446/IV (b)/1> and their mineral acid addition salts, wherein R1 represents a hydrogen atom, a C1-8 alkyl, a cycloalkyl, a phenyl or a phenyl-(C1-4-alkyl) group and R2 represents a C1-8 alkyl, a cycloalkyl, a phenyl or a phenyl-(C1-4-alkyl) group, and the preparation thereof by bringing together a compound of the general formula <FORM:0872446/IV (b)/2> and lithium hydride in a molar proportion of 1 to about 0.8 to 1.5 in an anhydrous inert organic solvent. Specification 829,663 is referred to.
ES0254043A 1958-12-23 1959-12-09 3-substituted azetidines Expired ES254043A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB41523/58A GB872446A (en) 1958-12-23 1958-12-23 3-substituted azetidines

Publications (1)

Publication Number Publication Date
ES254043A1 true ES254043A1 (en) 1960-07-01

Family

ID=10420076

Family Applications (2)

Application Number Title Priority Date Filing Date
ES0254043A Expired ES254043A1 (en) 1958-12-23 1959-12-09 3-substituted azetidines
ES0254041A Expired ES254041A1 (en) 1958-12-23 1959-12-09 3-substituted azetidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES0254041A Expired ES254041A1 (en) 1958-12-23 1959-12-09 3-substituted azetidines

Country Status (5)

Country Link
BE (4) BE585977A (en)
CH (4) CH391707A (en)
ES (2) ES254043A1 (en)
FR (2) FR177M (en)
GB (1) GB872446A (en)

Also Published As

Publication number Publication date
CH386427A (en) 1965-01-15
CH378327A (en) 1964-06-15
FR176M (en) 1961-02-13
GB872446A (en) 1961-07-12
BE585976A (en) 1960-04-19
CH391707A (en) 1965-05-15
ES254041A1 (en) 1960-07-01
BE585979A (en) 1960-04-19
CH378328A (en) 1964-06-15
BE585977A (en) 1960-04-19
FR177M (en) 1961-02-13
BE585978A (en) 1960-04-19

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