ES2530673T3 - Sensor - Google Patents

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Publication number
ES2530673T3
ES2530673T3 ES08788670T ES08788670T ES2530673T3 ES 2530673 T3 ES2530673 T3 ES 2530673T3 ES 08788670 T ES08788670 T ES 08788670T ES 08788670 T ES08788670 T ES 08788670T ES 2530673 T3 ES2530673 T3 ES 2530673T3
Authority
ES
Spain
Prior art keywords
transducer
sample
reagent
analyte
captive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08788670T
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English (en)
Inventor
Timothy Joseph Nicholas Carter
Steven Andrew Ross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vivacta Ltd
Original Assignee
Vivacta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivacta Ltd filed Critical Vivacta Ltd
Application granted granted Critical
Publication of ES2530673T3 publication Critical patent/ES2530673T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/171—Systems in which incident light is modified in accordance with the properties of the material investigated with calorimetric detection, e.g. with thermal lens detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G01N2021/1708—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids with piezotransducers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Radiation Pyrometers (AREA)

Abstract

Un método para detectar un analito en una muestra, que comprende las etapas de: exponer la muestra a un transductor que es capaz de transformar un cambio de energía en una señal eléctrica y que comprende un transductor piroeléctrico o piezoeléctrico que tiene un elemento piroeléctrico o piezoeléctrico y electrodos, el transductor que comprende fluoruro de polivinilideno y óxido de indio y estaño, el transductor que tiene, además, al menos un reactivo cautivo sobre o proximal al mismo, al menos el único reactivo cautivo que tiene un sitio activo que es capaz de unirse al analito; introducir un reactivo marcado en la muestra, en donde el reactivo marcado contiene un sitio activo para el analito o el reactivo cautivo y un marcador que es capaz de absorber la radiación electromagnética generada por una fuente de radiación para generar energía mediante desintegración no radiactiva, en donde el marcador se selecciona de una partícula metálica, una partícula polimérica coloreada, una partícula magnética, una partícula de carbono y una nanopartícula que comprende un material de núcleo no conductor y al menos una capa de cubierta metálica; permitir que el reactivo marcado se una al analito o el agente cautivo en un primer periodo en el cual el transductor se orienta de manera que se provoca que el reactivo marcado se asiente, al menos en parte, sobre el transductor; posteriormente, en un segundo periodo, provocar que el reactivo marcado se desprenda mediante la inversión del transductor con respecto a la muestra o invertir parcialmente el transductor con respecto a la muestra de manera que se provoca que el reactivo marcado se separe de la superficie del transductor; irradiar la muestra con radiación electromagnética durante el primero y el segundo periodos, transformar la energía generada en una señal eléctrica; detectar la señal eléctrica.
ES08788670T 2007-08-31 2008-08-13 Sensor Active ES2530673T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96930907P 2007-08-31 2007-08-31
GBGB0716968.3A GB0716968D0 (en) 2007-08-31 2007-08-31 Sensor
PCT/GB2008/050699 WO2009027726A1 (en) 2007-08-31 2008-08-13 Sensor

Publications (1)

Publication Number Publication Date
ES2530673T3 true ES2530673T3 (es) 2015-03-04

Family

ID=38617072

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08788670T Active ES2530673T3 (es) 2007-08-31 2008-08-13 Sensor

Country Status (8)

Country Link
US (2) US8524504B2 (es)
EP (1) EP2185932B1 (es)
JP (1) JP5749010B2 (es)
CN (1) CN101815942B (es)
CA (1) CA2695213C (es)
ES (1) ES2530673T3 (es)
GB (1) GB0716968D0 (es)
WO (1) WO2009027726A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2473220A (en) 2009-09-03 2011-03-09 Vivacta Ltd Analysis device comprising a transducer with stiffening elements
GB201000643D0 (en) * 2010-01-15 2010-03-03 Vivacta Ltd A method for sensing a chemical
BR112013013109B1 (pt) 2010-11-30 2021-02-09 Koninklijke Philips N.V. dispositivo sensor para a detecção de partículas magnéticas em uma câmara de amostras com uma superfície de contato em que as partículas magnéticas podem ser coletadas
GB201105828D0 (en) 2011-04-06 2011-05-18 Vivacta Ltd A device for detecting an analyte
CN102928606B (zh) * 2012-11-16 2015-10-07 武汉明德生物科技股份有限公司 多抗体标记的降钙素原快速检测试剂盒
JP6566704B2 (ja) * 2015-04-27 2019-08-28 デンカ生研株式会社 バックグラウンドノイズを低減したイムノクロマトグラフィー装置およびその低減方法

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GB8909701D0 (en) * 1989-04-27 1989-06-14 Health Lab Service Board Analytical apparatus
CA2118522A1 (en) * 1992-05-26 1993-12-09 Robert M. Ippolito Time dependent administration of oligosaccharides glycosides related to blood group determinants having a type i or type ii core structure in reducing inflammation in a sensitized mammal arising from exposure to an antigen
US5858666A (en) * 1996-08-29 1999-01-12 Biotechnology Research And Development Corporation Apparatus and method of detection employing an AC frequency sensor array
US6346376B1 (en) * 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
AU2740000A (en) * 1999-01-25 2000-08-07 Lockheed Martin Energy Research Corporation Multifunctional and multispectral biosensor devices and methods of use
JP2002122597A (ja) * 2000-08-09 2002-04-26 Mitsubishi Chemicals Corp 測定対象物の測定用チップ，測定対象物の測定装置及び測定対象物の測定方法
US20030170148A1 (en) * 2001-01-31 2003-09-11 Mcentee John F. Reaction chamber roll pump
US6899714B2 (en) 2001-10-03 2005-05-31 Vaughan Medical Technologies, Inc. Vertebral stabilization assembly and method
AU2003255721A1 (en) 2002-07-18 2004-02-09 Quest International Services B.V. Perfume compositions
GB0308324D0 (en) * 2003-04-10 2003-05-14 Piezoptic Ltd A chemical sensing device
CA2527338A1 (en) * 2003-06-05 2004-12-16 Bioprocessors Corp. Apparatus and method for manipulating substrates
JP3816502B2 (ja) 2003-08-04 2006-08-30 博 冨安 超臨界水又は亜臨界水を使用した有機物の酸化方法
JP2005319407A (ja) * 2004-05-10 2005-11-17 Hitachi Ltd 圧電デバイスを用いた機器
ATE417957T1 (de) 2004-07-20 2009-01-15 Schwihag Ag Querschwelle mit verstellvorrichtung für weichenzungen
US7169617B2 (en) 2004-08-19 2007-01-30 Fujitsu Limited Device and method for quantitatively determining an analyte, a method for determining an effective size of a molecule, a method for attaching molecules to a substrate, and a device for detecting molecules
JP2008544246A (ja) * 2005-06-17 2008-12-04 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 正確な磁気バイオセンサー
CN101223820B (zh) 2005-07-15 2011-05-04 松下电器产业株式会社 信号处理装置
HUP0500730A2 (en) 2005-07-29 2007-02-28 Richter Gedeon Vegyuszeti Gyar 1,2-diaryl-heterocyclic compounds, their preparation, pharmaceutical compositions comprising thereof and their use
JP2009529888A (ja) * 2006-03-14 2009-08-27 ユニバーシティ オブ ロチェスター 超薄多孔質メンブレンを有する細胞培養装置およびその使用
WO2007107716A1 (en) * 2006-03-17 2007-09-27 Vivacta Ltd A chemical sensing device
JP2010533281A (ja) * 2006-06-06 2010-10-21 ビバクタ、リミテッド 化学物質の検知方法
US20080026451A1 (en) * 2006-06-15 2008-01-31 Braman Jeffrey C System for isolating biomolecules from a sample

Also Published As

Publication number Publication date
CA2695213A1 (en) 2009-03-05
JP5749010B2 (ja) 2015-07-15
JP2010538253A (ja) 2010-12-09
EP2185932B1 (en) 2015-01-28
US9638691B2 (en) 2017-05-02
GB0716968D0 (en) 2007-10-10
US8524504B2 (en) 2013-09-03
CN101815942A (zh) 2010-08-25
CN101815942B (zh) 2013-09-11
US20100285609A1 (en) 2010-11-11
CA2695213C (en) 2017-01-10
EP2185932A1 (en) 2010-05-19
US20130315783A1 (en) 2013-11-28
WO2009027726A1 (en) 2009-03-05

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